PMID- 37964126 OWN - NLM STAT- MEDLINE DCOM- 20231216 LR - 20231216 IS - 1433-7347 (Electronic) IS - 0942-2056 (Linking) VI - 31 IP - 12 DP - 2023 Dec TI - Low central sensitisation inventory score is associated with better post-operative outcomes of osteotomy around the knee. PG - 5896-5904 LID - 10.1007/s00167-023-07646-y [doi] AB - PURPOSE: The purpose of this study was to investigate the potential association between central sensitisation inventory (CSI) scores and post-operative patient-reported outcomes (PROs) in patients underwent osteotomy around the knee (OAK), with a CSI cut-off score specific for knee osteoarthritis. METHODS: CSI scores were collected from 173 patients who underwent OAK, along with their knee injury and osteoarthritis outcome score (KOOS) and pain numeric rating scale (NRS) scores. Patients were divided into high-CSI score group and low-CSI score group with a cut-off score of 17. Multivariate linear regression was performed to test the association between CSI scores and post-operative outcomes. Pre-surgery KOOS and NRS scores and the rate of attainment of minimal clinically important difference (MCID) of KOOS scores was analysed as secondary outcomes. RESULTS: Low-CSI score group had significantly higher post-operative KOOS scores and lower pain NRS scores compared to the high-CSI score group (< p = 0.01) after adjusting for confounding factors. For pre-operative scores, only the KOOS-Symptom score was significantly different between the groups (64.7 +/- 20.1 when CSI < 17 vs.55.1 +/- 19.7 when CSI >/= 17; p = 0.008). The low-CSI score group had significantly higher MCID achievement rates of KOOS-Pain, Symptom, and ADL than the high-CSI score group (86% vs. 68%; 74% vs. 55%; 86% vs. 67%, respectively; P < 0.05). CONCLUSIONS: This study established an association between post-operative CSI scores >/= 17 and poorer outcomes following OAK, highlighting the potential value of the CSI in identifying patients in need of more comprehensive peri-operative pain management. LEVEL OF EVIDENCE: Level III. Retrospective comparative study. CI - (c) 2023. The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA). FAU - Ding, Hao AU - Ding H AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Koga, Hideyuki AU - Koga H AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Katagiri, Hiroki AU - Katagiri H AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. AD - Department of Orthopaedic Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan. FAU - Hasegawa, Shoichi AU - Hasegawa S AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Anzai, Tatushiko AU - Anzai T AD - Department of Biostatistics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Katakura, Mai AU - Katakura M AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Yoshihara, Aritoshi AU - Yoshihara A AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Amemiya, Masaki AU - Amemiya M AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Hoshino, Takashi AU - Hoshino T AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Ozeki, Nobutake AU - Ozeki N AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. AD - Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Nakamura, Tomomasa AU - Nakamura T AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. FAU - Nakagawa, Yusuke AU - Nakagawa Y AUID- ORCID: 0000-0003-0170-9743 AD - Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. ynakagawa.orj@tmd.ac.jp. LA - eng PT - Journal Article DEP - 20231114 PL - Germany TA - Knee Surg Sports Traumatol Arthrosc JT - Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA JID - 9314730 SB - IM MH - Humans MH - Central Nervous System Sensitization MH - Retrospective Studies MH - *Arthroplasty, Replacement, Knee/adverse effects MH - Treatment Outcome MH - Knee Joint/surgery MH - *Osteoarthritis, Knee/surgery/etiology MH - Pain/surgery MH - Patient Reported Outcome Measures MH - Osteotomy OTO - NOTNLM OT - Central sensitisation inventory OT - Osteotomy around the knee OT - Pain OT - Patient-reported outcomes EDAT- 2023/11/15 00:41 MHDA- 2023/12/17 13:19 CRDT- 2023/11/14 23:43 PHST- 2023/08/09 00:00 [received] PHST- 2023/10/21 00:00 [accepted] PHST- 2023/12/17 13:19 [medline] PHST- 2023/11/15 00:41 [pubmed] PHST- 2023/11/14 23:43 [entrez] AID - 10.1007/s00167-023-07646-y [pii] AID - 10.1007/s00167-023-07646-y [doi] PST - ppublish SO - Knee Surg Sports Traumatol Arthrosc. 2023 Dec;31(12):5896-5904. doi: 10.1007/s00167-023-07646-y. Epub 2023 Nov 14.