PMID- 37964583
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1804-7521 (Electronic)
IS  - 1213-8118 (Linking)
VI  - 167
IP  - 4
DP  - 2023 Dec
TI  - The contribution of new methods in cytology for increasing sensitivity in the 
      diagnosis of extrahepatic bile duct lesions.
PG  - 309-318
LID - 10.5507/bp.2023.041 [doi]
AB  - The aim of this review is to provide a comprehensive analysis of the existing 
      literature pertaining to cytology of extrahepatic bile ducts. A search using the 
      keywords "biliary brush cytology" was conducted in the PubMed database, with a 
      focus on recent articles. The inclusion criteria primarily encompassed 
      publications addressing problematic biliary stenosis. Emphasis was placed on 
      identifying articles that explored innovative or less-utilized examination 
      techniques aimed at enhancing the sensitivity of cytological examination. This 
      review presents a comprehensive overview of the various types of materials used 
      in sampling and the corresponding sampling methods. Additionally, it explores 
      cytological and cytogenetic techniques, such as fluorescence in situ 
      hybridization (FISH) and genetic methods (miRNA, NGS, cfDNA). These techniques 
      possess the potential to improve the accuracy of diagnosing bile duct tumors, 
      although their sensitivity varies. Furthermore, their utilization can facilitate 
      early therapy, which plays a crucial role in patient prognosis. Each examination 
      is always dependent on the quality and quantity of material delivered. A higher 
      sensitivity of these examinations can be achieved by combining biliary cytology 
      and other complementary methods.
FAU - Kurfurstova, Daniela
AU  - Kurfurstova D
AD  - Department of Clinical and Molecular Pathology, University Hospital Olomouc and 
      Faculty of Medicine and Dentistry, Palacky University Olomouc, 779 00 Olomouc, 
      Czech Republic.
FAU - Slobodova, Zuzana
AU  - Slobodova Z
AD  - Department of Clinical and Molecular Pathology, University Hospital Olomouc and 
      Faculty of Medicine and Dentistry, Palacky University Olomouc, 779 00 Olomouc, 
      Czech Republic.
FAU - Zoundjiekpon, Vincent
AU  - Zoundjiekpon V
AD  - 2nd Department of Internal Medicine - Gastroenterology and Geriatrics, University 
      Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University 
      Olomouc, 779 00 Olomouc, Czech Republic.
FAU - Urban, Ondrej
AU  - Urban O
AD  - 2nd Department of Internal Medicine - Gastroenterology and Geriatrics, University 
      Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University 
      Olomouc, 779 00 Olomouc, Czech Republic.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20231114
PL  - Czech Republic
TA  - Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
JT  - Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, 
      Czechoslovakia
JID - 101140142
SB  - IM
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Prospective Studies
MH  - *Bile Ducts, Extrahepatic/pathology
MH  - Cytodiagnosis/methods
MH  - *Bile Duct Neoplasms/diagnosis/genetics/pathology
MH  - Sensitivity and Specificity
OTO - NOTNLM
OT  - cytology, fluorescence in situ hybridization
OT  - diagnosis of biliary strictures
OT  - next generation sequencing
OT  - sensitivity
COIS- The authors report no conflicts of interest in this work.
EDAT- 2023/11/15 06:42
MHDA- 2023/12/17 13:19
CRDT- 2023/11/15 03:46
PHST- 2023/03/21 00:00 [received]
PHST- 2023/10/12 00:00 [accepted]
PHST- 2023/12/17 13:19 [medline]
PHST- 2023/11/15 06:42 [pubmed]
PHST- 2023/11/15 03:46 [entrez]
AID - 10.5507/bp.2023.041 [doi]
PST - ppublish
SO  - Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2023 Dec;167(4):309-318. 
      doi: 10.5507/bp.2023.041. Epub 2023 Nov 14.