PMID- 37964689 OWN - NLM STAT- MEDLINE DCOM- 20240214 LR - 20240405 IS - 2057-4347 (Electronic) IS - 2057-4347 (Linking) VI - 10 IP - 1 DP - 2024 Feb TI - Evaluation of salivary transferrin in patients with oral squamous cell carcinoma. PG - e809 LID - 10.1002/cre2.809 [doi] LID - e809 AB - OBJECTIVES: About 94% of oral cancers are squamous cell carcinomas (OSCCs). Its occurrence is age-related due to some factors. Salivary biomarkers have good susceptibility to OSCC's early diagnosis. Moreover, since the clinical diagnosis of advanced stages of OSCC is feasible, its prognosis is very poor. MATERIAL AND METHODS: According to inclusion and exclusion criteria, 40 OSCC patients and 40 healthy people were selected, and 5 mL of saliva were prepared from each person. The quantity of saline transferrin was computed. After that, the data were analyzed. RESULTS: Our study results demonstrated that the mean and standard deviation of the salivary transferrin in the control group were 1.234 mL and 0.374, respectively, and in the case group, it was equal to 2.512 mL for the mean and 0.463 for the standard deviation. There was a statistically substantial difference between the mean of the salivary transferrin variable in the two study groups. CONCLUSION: In conclusion, the mean concentration of salivary transferrin in the case group was higher than in the control group. CI - (c) 2023 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd. FAU - Tavakoli, Fatemeh AU - Tavakoli F AUID- ORCID: 0000-0002-3297-5465 AD - Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Ghavimi, Mohammad Ali AU - Ghavimi MA AD - Department, of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Fakhrzadeh, Vahid AU - Fakhrzadeh V AD - Department of Prosthodontics, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Abdolzadeh, Dorna AU - Abdolzadeh D AD - School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Afshari, Aylar AU - Afshari A AUID- ORCID: 0000-0002-2079-4317 AD - School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Eslami, Hosein AU - Eslami H AUID- ORCID: 0000-0002-0050-5872 AD - Department of Oral and Maxillofacial Medicine, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. LA - eng GR - None/ PT - Journal Article DEP - 20231114 PL - United States TA - Clin Exp Dent Res JT - Clinical and experimental dental research JID - 101692332 RN - 0 (Transferrin) RN - 0 (Biomarkers, Tumor) SB - IM MH - Humans MH - Squamous Cell Carcinoma of Head and Neck MH - *Carcinoma, Squamous Cell/diagnosis/pathology MH - *Mouth Neoplasms/diagnosis/pathology MH - Transferrin MH - Biomarkers, Tumor MH - *Head and Neck Neoplasms PMC - PMC10860556 OTO - NOTNLM OT - oral squamous cell carcinoma OT - salivary biomarkers OT - transferrin COIS- The authors declare no conflict of interest. EDAT- 2023/11/15 06:42 MHDA- 2024/02/12 15:44 PMCR- 2023/11/14 CRDT- 2023/11/15 03:52 PHST- 2023/10/23 00:00 [revised] PHST- 2023/05/23 00:00 [received] PHST- 2023/10/24 00:00 [accepted] PHST- 2024/02/12 15:44 [medline] PHST- 2023/11/15 06:42 [pubmed] PHST- 2023/11/15 03:52 [entrez] PHST- 2023/11/14 00:00 [pmc-release] AID - CRE2809 [pii] AID - 10.1002/cre2.809 [doi] PST - ppublish SO - Clin Exp Dent Res. 2024 Feb;10(1):e809. doi: 10.1002/cre2.809. Epub 2023 Nov 14.