PMID- 37965524
OWN - NLM
STAT- MEDLINE
DCOM- 20231116
LR  - 20240424
IS  - 2296-2565 (Electronic)
IS  - 2296-2565 (Linking)
VI  - 11
DP  - 2023
TI  - Association and interactions between mixed exposure to trace elements and the 
      prevalence of kidney stones: a study of NHANES 2017-2018.
PG  - 1251637
LID - 10.3389/fpubh.2023.1251637 [doi]
LID - 1251637
AB  - BACKGROUND: The association between exposure to trace elements mixture and the 
      prevalence of kidney stones and the interactions between elements are unclear. 
      The aim of this study was to explore the association between exposure to trace 
      elements mixture and the prevalence of kidney stones and the interactions between 
      the elements. METHODS: A total of 1,244 participants (139 kidney stone formers 
      and 1,105 non-stone former participants) in NHANES 2017-2018 were included. The 
      exposure to trace elements was evaluated by measuring their concentration in 
      urine samples. Three methods, Logistic regression, quantile-based g computation 
      (qgcomp), and Bayesian kernel machine regression (BKMR), were used for analysis. 
      RESULTS: According to the results from qgcomp and BKMR, a negative association 
      was found between exposure to the 13 trace elements and the prevalence of kidney 
      stones [OR = 0.50 (0.32, 0.78)]. Subgroup analysis revealed that Co, As, and 
      iodine in the whole population, Co, As, and Ni in males, and Cs, iodine, and Sb 
      in females, were most strongly associated with kidney stones. Kidney stone was 
      found to be positively correlated with Co and negatively correlated with the 
      other elements. Besides, there were significant interactions between Ni and Pb in 
      the whole population, Co and iodine in males, and Pb and iodine in females. 
      CONCLUSION: There was a negative association between exposure to the mixture of 
      13 trace elements and the prevalence of kidney stones.
CI  - Copyright (c) 2023 Wang, Zhang, Ma, Yang, Dang, Cao, Shi, Ouyang, Pan and Hu.
FAU - Wang, Xiao
AU  - Wang X
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Zhang, Jia
AU  - Zhang J
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Ma, Zhibin
AU  - Ma Z
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Yang, Yaya
AU  - Yang Y
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Dang, Ying
AU  - Dang Y
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Cao, Shuting
AU  - Cao S
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Shi, Xiaoru
AU  - Shi X
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Ouyang, Changping
AU  - Ouyang C
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Pan, Jinhua
AU  - Pan J
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
FAU - Hu, Xiaobin
AU  - Hu X
AD  - Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou 
      University, Lanzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20231026
PL  - Switzerland
TA  - Front Public Health
JT  - Frontiers in public health
JID - 101616579
RN  - 0 (Trace Elements)
RN  - 2P299V784P (Lead)
RN  - 9679TC07X4 (Iodine)
SB  - IM
MH  - Female
MH  - Male
MH  - Humans
MH  - *Trace Elements
MH  - Prevalence
MH  - Bayes Theorem
MH  - Lead
MH  - Nutrition Surveys
MH  - *Kidney Calculi/epidemiology/etiology
MH  - *Iodine
PMC - PMC10642183
OTO - NOTNLM
OT  - BKMR
OT  - NHANES
OT  - kidney stone
OT  - qgcomp
OT  - trace element
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/11/15 06:42
MHDA- 2023/11/16 06:44
PMCR- 2023/10/26
CRDT- 2023/11/15 04:29
PHST- 2023/07/28 00:00 [received]
PHST- 2023/10/09 00:00 [accepted]
PHST- 2023/11/16 06:44 [medline]
PHST- 2023/11/15 06:42 [pubmed]
PHST- 2023/11/15 04:29 [entrez]
PHST- 2023/10/26 00:00 [pmc-release]
AID - 10.3389/fpubh.2023.1251637 [doi]
PST - epublish
SO  - Front Public Health. 2023 Oct 26;11:1251637. doi: 10.3389/fpubh.2023.1251637. 
      eCollection 2023.