PMID- 37968555 OWN - NLM STAT- MEDLINE DCOM- 20240115 LR - 20240123 IS - 1573-2568 (Electronic) IS - 0163-2116 (Linking) VI - 69 IP - 1 DP - 2024 Jan TI - Risks of Proton Pump Inhibitors in Patients with Cirrhosis: Please Peruse the Indications. PG - 7-9 LID - 10.1007/s10620-023-08153-3 [doi] AB - The use of proton pump inhibitor (PPI) in cirrhotic patients can be associated with increased risks of long-term mortality, decompensation, hepatic encephalopathy, spontaneous bacterial peritonitis, and infection, but not with short-term mortality. Ensure clear indications at lowest effective dose of is mandatory for the use of PPI among cirrhotic patients. CI - (c) 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. FAU - Low, En Xian Sarah AU - Low EXS AD - Endoscopy Center for Diagnosis and Treatment, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. FAU - Wang, Yen-Po AU - Wang YP AD - Endoscopy Center for Diagnosis and Treatment, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. AD - Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. FAU - Lu, Ching-Liang AU - Lu CL AD - Endoscopy Center for Diagnosis and Treatment, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. cllu@nycu.edu.tw. AD - Institute of Brain Science, National Yang Ming Chiao Tung Univeristy, Taipei, Taiwan. cllu@nycu.edu.tw. AD - Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. cllu@nycu.edu.tw. LA - eng PT - Editorial DEP - 20231115 PL - United States TA - Dig Dis Sci JT - Digestive diseases and sciences JID - 7902782 RN - 0 (Proton Pump Inhibitors) SB - IM MH - Humans MH - Proton Pump Inhibitors/adverse effects MH - Liver Cirrhosis/complications/drug therapy MH - *Hepatic Encephalopathy/etiology MH - *Peritonitis/microbiology MH - *Bacterial Infections/drug therapy/complications OTO - NOTNLM OT - Cirrhosis OT - Hepatic decompensation OT - Hepatocellular carcinoma OT - Proton pump inhibitors OT - Spontaneous bacterial peritonitis EDAT- 2023/11/16 06:45 MHDA- 2024/01/15 12:43 CRDT- 2023/11/16 00:06 PHST- 2023/09/28 00:00 [received] PHST- 2023/10/09 00:00 [accepted] PHST- 2024/01/15 12:43 [medline] PHST- 2023/11/16 06:45 [pubmed] PHST- 2023/11/16 00:06 [entrez] AID - 10.1007/s10620-023-08153-3 [pii] AID - 10.1007/s10620-023-08153-3 [doi] PST - ppublish SO - Dig Dis Sci. 2024 Jan;69(1):7-9. doi: 10.1007/s10620-023-08153-3. Epub 2023 Nov 15.