PMID- 37970081
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231117
IS  - 2516-8290 (Electronic)
IS  - 2516-8290 (Linking)
VI  - 5
IP  - 10
DP  - 2023
TI  - Duped by dumping syndrome: non-endemic Vibrio cholerae bacteremia in an 
      immunocompetent host with gastric bypass surgery, a case report.
LID - 000517.v3 [pii]
LID - 10.1099/acmi.0.000517.v3 [doi]
AB  - Extra-intestinal infection with non-O1/non-O139 strains of Vibrio cholerae (NOVC) 
      is rare, though bacteremia and hepatobiliary manifestations have been reported. 
      Reduced stomach acid, or hypochlorhydria, can increase risk of V. cholerae 
      infection. We describe a 42-year-old woman with hypochlorhydria due to untreated 
      Helicobacter pylori infection, gastric-bypass surgery, and chronic proton pump 
      inhibitors (PPI) exposure, who developed acute diarrhoea following raw oyster 
      consumption. Her symptoms were attributed to rapid gastric emptying (dumping 
      syndrome) after a negative limited stool work-up. She had persistent diarrhoea, 
      weight loss, and after 5 months was admitted with acute cholecystitis and NOVC 
      bacteremia, requiring cholecystectomy. This is the first reported case of NOVC 
      bacteremia and cholecystitis in a patient with gastric bypass. This case 
      highlights the potential for NOVC biliary carriage, the role of hypochlorhydria 
      as a risk factor for Vibrio infection, and the importance of excluding infectious 
      diarrhoea in patients with new onset of symptoms compatible with dumping syndrome 
      and a relevant travel history.
CI  - (c) 2023 The Authors.
FAU - Reyes, Fabiola
AU  - Reyes F
AD  - Brigham and Women's Hospital, Division of Infectious Diseases, 75 Francis St, 
      Boston, MA, 02115, USA.
AD  - Tufts Medical Center, Department of Pathology, 800 Washington St. Boston, MA, 
      02111, USA.
FAU - Pecora, Nicole
AU  - Pecora N
AD  - Brigham and Women's Hospital, Department of Pathology, 75 Francis St, Boston, MA, 
      02115, USA.
FAU - Weiss, Zoe Freeman
AU  - Weiss ZF
AUID- ORCID: 0000-0003-2931-3660
AD  - Brigham and Women's Hospital, Division of Infectious Diseases, 75 Francis St, 
      Boston, MA, 02115, USA.
AD  - Tufts Medical Center, Department of Pathology, 800 Washington St. Boston, MA, 
      02111, USA.
AD  - Brigham and Women's Hospital, Department of Pathology, 75 Francis St, Boston, MA, 
      02115, USA.
AD  - Tufts Medical Center, Division of Geographic Medicine and Infectious Diseases, 
      800 Washington St. Boston, MA, 02111, USA.
LA  - eng
PT  - Case Reports
DEP - 20231031
PL  - England
TA  - Access Microbiol
JT  - Access microbiology
JID - 101746927
PMC - PMC10634482
OTO - NOTNLM
OT  - NOVC
OT  - bacteremia
OT  - case report
OT  - gastric bypass
OT  - infectious diarrhea
OT  - non-epidemicVibrio cholerae
COIS- Authors have no competing interests.
EDAT- 2023/11/16 06:45
MHDA- 2023/11/16 06:46
PMCR- 2023/10/31
CRDT- 2023/11/16 04:27
PHST- 2022/11/02 00:00 [received]
PHST- 2023/10/13 00:00 [accepted]
PHST- 2023/11/16 06:46 [medline]
PHST- 2023/11/16 06:45 [pubmed]
PHST- 2023/11/16 04:27 [entrez]
PHST- 2023/10/31 00:00 [pmc-release]
AID - 000517.v3 [pii]
AID - 10.1099/acmi.0.000517.v3 [doi]
PST - epublish
SO  - Access Microbiol. 2023 Oct 31;5(10):000517.v3. doi: 10.1099/acmi.0.000517.v3. 
      eCollection 2023.