PMID- 37971456
OWN - NLM
STAT- MEDLINE
DCOM- 20240408
LR  - 20240408
IS  - 1078-6791 (Print)
IS  - 1078-6791 (Linking)
VI  - 30
IP  - 2
DP  - 2024 Feb
TI  - Examining the Correlation between Allergic Conjunctivitis and Allergic Rhinitis.
PG  - 106-110
LID - AT9516 [pii]
AB  - OBJECTIVE: This study aims to assess the correlation between allergic 
      conjunctivitis (AC) and allergic rhinitis (AR). METHODS: A total of 462 patients 
      diagnosed with either allergic conjunctivitis or allergic rhinitis and treated at 
      our hospital from January 2018 to December 2020 were included. Patients were 
      categorized into two groups, the AC group and the AR group, based on their 
      initial department of consultation. The AC group comprised 232 patients diagnosed 
      with allergic conjunctivitis in the ophthalmology department, while the AR group 
      consisted of 230 patients diagnosed with allergic rhinitis in the ENT department. 
      Allergen analysis was conducted on patients presenting with both AC and AR and 
      conjunctival and nasal mucosal scrapings were performed to examine eosinophil 
      presence. The study analyzed the association between allergic AC and AR. RESULTS: 
      In the AC group, 174 patients (75.00%) had concurrent AR, while in the AR group, 
      169 patients (73.48%) had concurrent AC. Inhalant allergen testing among patients 
      with concurrent AC and AR revealed that the primary inhalant allergens were dust 
      mites, house dust, and fungi, with specific immunoglobulin E (IgE) positivity of 
      91.23%. Testing for food allergens identified fish, shrimp, and crab as ingestive 
      allergens, with a specific IgE positivity of 58.58%. Eosinophil presence was 
      assessed through conjunctival and nasal mucosal scrapings in patients with 
      concurrent AC and AR. Eosinophils were detected in 188 cases (54.81%) through 
      conjunctival scraping and 197 cases (57.43%) through nasal mucosal scraping, with 
      no significant differences observed (P > .05). CONCLUSIONS: AC and AR share a 
      common pathophysiological process and allergen profile, with the conjunctiva and 
      nasal mucosa serving as sites of allergic reactions. This study suggests the 
      integration of AC prevention and treatment into AR prevention strategies.
FAU - Xu, Fang
AU  - Xu F
FAU - Yang, Kunna
AU  - Yang K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Altern Ther Health Med
JT  - Alternative therapies in health and medicine
JID - 9502013
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Humans
MH  - *Conjunctivitis, Allergic/epidemiology/diagnosis
MH  - *Rhinitis, Allergic/epidemiology
MH  - Allergens
MH  - Immunoglobulin E
EDAT- 2023/11/17 15:32
MHDA- 2024/04/08 06:43
CRDT- 2023/11/16 10:52
PHST- 2024/04/08 06:43 [medline]
PHST- 2023/11/17 15:32 [pubmed]
PHST- 2023/11/16 10:52 [entrez]
AID - AT9516 [pii]
PST - ppublish
SO  - Altern Ther Health Med. 2024 Feb;30(2):106-110.