PMID- 3797218
OWN - NLM
STAT- MEDLINE
DCOM- 19870203
LR  - 20190726
IS  - 0031-6768 (Print)
IS  - 0031-6768 (Linking)
VI  - 407
IP  - 6
DP  - 1986 Dec
TI  - Renal hemodynamics and natriuresis during water immersion in normal humans.
PG  - 638-42
AB  - The renal vascular and functional responses to acute "central hypervolemia" by 
      water immersion to the neck were determined in six normal subjects. During 
      isotonic-isooncotic expansion by water immersion there was a significant increase 
      in urine flow from 1.1 +/- 0.1 to 6.9 +/- 1.0 ml/min (p less than 0.05) and 
      sodium excretion from 99.1 +/- 8.8 to 300 +/- 28 mu Eq/min (p less than 0.05). 
      Glomerular filtration rate did not change while renal blood flow significantly 
      increased during water immersion. Deep intrarenal venous pressure (IRVP) 
      increased from 18.2 +/- 1.4 to 32 +/- 1.7 mmHg (p less than 0.05) while mean 
      arterial pressure was unchanged. This marked natriuresis seen during water 
      immersion was associated with reduced renal vascular resistance and increased 
      deep intrarenal venous pressure demonstrating that continued natriuresis could 
      relate to increased capillary hydrostatic pressure.
FAU - Coruzzi, P
AU  - Coruzzi P
FAU - Biggi, A
AU  - Biggi A
FAU - Musiari, L
AU  - Musiari L
FAU - Ravanetti, C
AU  - Ravanetti C
FAU - Novarini, A
AU  - Novarini A
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Pflugers Arch
JT  - Pflugers Archiv : European journal of physiology
JID - 0154720
RN  - 9005-80-5 (Inulin)
RN  - RWP5GA015D (Potassium)
RN  - Y79XT83BJ9 (p-Aminohippuric Acid)
SB  - IM
MH  - Adult
MH  - Blood Pressure
MH  - Hemodynamics
MH  - Humans
MH  - *Immersion
MH  - Inulin/urine
MH  - Kidney/*physiology
MH  - Male
MH  - *Natriuresis
MH  - Potassium/urine
MH  - p-Aminohippuric Acid/urine
EDAT- 1986/12/01 00:00
MHDA- 1986/12/01 00:01
CRDT- 1986/12/01 00:00
PHST- 1986/12/01 00:00 [pubmed]
PHST- 1986/12/01 00:01 [medline]
PHST- 1986/12/01 00:00 [entrez]
AID - 10.1007/BF00582645 [doi]
PST - ppublish
SO  - Pflugers Arch. 1986 Dec;407(6):638-42. doi: 10.1007/BF00582645.