PMID- 37991179
OWN - NLM
STAT- MEDLINE
DCOM- 20231127
LR  - 20231228
IS  - 1442-200X (Electronic)
IS  - 1328-8067 (Linking)
VI  - 65
IP  - 1
DP  - 2023 Jan-Dec
TI  - Non-contrast magnetic resonance angiography for systemic artery evaluation in 
      Kawasaki disease.
PG  - e15704
LID - 10.1111/ped.15704 [doi]
AB  - BACKGROUND: Kawasaki disease (KD) is a systemic vasculitis; systemic arteries 
      other than the coronary arteries should therefore also be evaluated. This study 
      investigated the feasibility of evaluating coronary aneurysms, systemic artery 
      aneurysms (SAAs), and cerebrovascular diseases in patients with KD using 
      non-contrast magnetic resonance angiography (NC-MRA). METHODS: Coronary artery 
      protocols, including coronary magnetic resonance angiography (MRA) and vessel 
      wall imaging, were performed in 57 examinations of 28 patients. Systemic artery 
      protocol, including SAA scans and head MRA, along with coronary artery protocol, 
      were performed in 42 examinations of 42 patients. The image quality of the SAAs 
      was evaluated on a 4-point scale. Examination time and sedation dosage were 
      compared between the protocols. The presence of SAAs and cerebrovascular disease 
      was also evaluated. RESULTS: The image quality score of SAAs was 4 (interquartile 
      range [IQR]: 4-4) for the aorta, 4 (IQR: 3-4) for the subclavian artery, 4 (IQR: 
      3-4) for the renal artery, and 3 (IQR: 3-4) for the iliac artery. No differences 
      were found between examination time (47.0 [IQR: 43.0-61.0] min vs. 51.0 [IQR: 
      45.0-60.0] min, p = 0.48) and sedative dose (4.63 [IQR: 3.93-5.79] mg/kg vs. 4.21 
      [IQR: 3.56-5.71] mg/kg, p = 0.37) between the protocols. Systemic artery protocol 
      detected SAAs in three patients (7.1%), and cerebrovascular disease was not 
      detected. CONCLUSIONS: Evaluating the coronary and systemic arteries in patients 
      with KD using NC-MRA on a single examination was possible without compromising 
      examination time or sedation dose. The systemic artery protocol was useful in 
      finding SAAs.
CI  - (c) 2023 Japan Pediatric Society.
FAU - Nonaka, Haruki
AU  - Nonaka H
AUID- ORCID: 0000-0001-9905-986X
AD  - Department of Radiological Technology, Tsuchiya General Hospital, Hiroshima, 
      Japan.
FAU - Tahara, Masahiro
AU  - Tahara M
AD  - Hiroshima central street Children's Clinic, Hiroshima, Japan.
FAU - Sanada, Kazuya
AU  - Sanada K
AD  - Department of Pediatric Cardiology, Shizuoka Children's Hospital, Shizuoka, 
      Japan.
FAU - Okano, Mio
AU  - Okano M
AD  - Department of Radiological Technology, Tsuchiya General Hospital, Hiroshima, 
      Japan.
FAU - Morikawa, Yuko
AU  - Morikawa Y
AD  - Department of Radiological Technology, Tsuchiya General Hospital, Hiroshima, 
      Japan.
FAU - Yoshiura, Takayuki
AU  - Yoshiura T
AD  - Department of Radiological Technology, Tsuchiya General Hospital, Hiroshima, 
      Japan.
FAU - Nitta, Tetsuya
AU  - Nitta T
AD  - Nitta Pediatric Clinic, Hiroshima, Japan.
FAU - Urayama, Kotaro
AU  - Urayama K
AD  - Department of Pediatric Cardiology, Tsuchiya General Hospital, Hiroshima, Japan.
FAU - Yoneyama, Masami
AU  - Yoneyama M
AD  - Philips Japan, Tokyo, Japan.
FAU - Imada, Naoyuki
AU  - Imada N
AD  - Department of Health Care, North Hiroshima Hospital, Hiroshima, Japan.
FAU - Sato, Tomoyasu
AU  - Sato T
AD  - Department of Diagnostic Radiology, Tsuchiya General Hospital, Hiroshima, Japan.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Pediatr Int
JT  - Pediatrics international : official journal of the Japan Pediatric Society
JID - 100886002
RN  - 0 (Contrast Media)
SB  - IM
MH  - Humans
MH  - Magnetic Resonance Angiography/methods
MH  - *Mucocutaneous Lymph Node Syndrome/diagnosis/diagnostic imaging
MH  - Renal Artery/pathology
MH  - *Coronary Aneurysm/diagnosis
MH  - Iliac Artery
MH  - Contrast Media
OTO - NOTNLM
OT  - Kawasaki disease
OT  - complication
OT  - magnetic resonance imaging
OT  - non-contrast magnetic resonance angiography
OT  - systemic artery aneurysm
EDAT- 2023/11/22 12:43
MHDA- 2023/11/27 16:18
CRDT- 2023/11/22 07:24
PHST- 2023/09/24 00:00 [revised]
PHST- 2023/05/22 00:00 [received]
PHST- 2023/10/12 00:00 [accepted]
PHST- 2023/11/27 16:18 [medline]
PHST- 2023/11/22 12:43 [pubmed]
PHST- 2023/11/22 07:24 [entrez]
AID - 10.1111/ped.15704 [doi]
PST - ppublish
SO  - Pediatr Int. 2023 Jan-Dec;65(1):e15704. doi: 10.1111/ped.15704.