PMID- 38004153 OWN - NLM STAT- MEDLINE DCOM- 20231127 LR - 20231127 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 15 IP - 22 DP - 2023 Nov 12 TI - Post-Exercise Rehydration in Athletes: Effects of Sodium and Carbohydrate in Commercial Hydration Beverages. LID - 10.3390/nu15224759 [doi] LID - 4759 AB - The effects of varying sodium (Na) and carbohydrate (CHO) in oral rehydration solutions (ORS) and sports drinks (SD) for rehydration following exercise are unclear. We compared an ORS and SD for the percent of fluid retained (%FR) following exercise-induced dehydration and hypothesized a more complete rehydration for the ORS (45 mmol Na/L and 2.5% CHO) and that the %FR for the ORS and SD (18 mmol Na/L and 6% CHO) would exceed the water placebo (W). A placebo-controlled, randomized, double-blind clinical trial was conducted. To induce 2.6% body mass loss (BML, p > 0.05 between treatments), 26 athletes performed three 90 min interval training sessions without drinking fluids. Post-exercise, participants replaced 100% of BML and were observed for 3.5 h for the %FR. Mean +/- SD for the %FR at 3.5 h was 58.1 +/- 12.6% (W), 73.9 +/- 10.9% (SD), and 76.9 +/- 8.0% (ORS). The %FR for the ORS and SD were similar and greater than the W (p < 0.05 ANOVA and Tukey HSD). Two-way ANOVA revealed a significant interaction with the ORS having greater suppression of urine production in the first 60 min vs. W (SD did not differ from W). By 3.5 h, the ORS and SD promoted greater rehydration than did W, but the pattern of rehydration early in recovery favored the ORS. FAU - Ly, Nhu Q AU - Ly NQ AD - Independent Researcher, Charlotte, NC 28278, USA. FAU - Hamstra-Wright, Karrie L AU - Hamstra-Wright KL AD - Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60608, USA. FAU - Horswill, Craig A AU - Horswill CA AUID- ORCID: 0000-0002-3695-9577 AD - Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60608, USA. LA - eng GR - ANUS1307/EAS Division of Abbott Nutrition/ PT - Journal Article PT - Randomized Controlled Trial DEP - 20231112 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 9NEZ333N27 (Sodium) RN - 0 (Carbohydrates) SB - IM MH - Humans MH - *Sodium MH - *Fluid Therapy MH - Water-Electrolyte Balance MH - Beverages MH - Carbohydrates MH - Athletes MH - Dehydration/therapy PMC - PMC10674530 OTO - NOTNLM OT - carbohydrate OT - dehydration OT - oral rehydration solution OT - sodium OT - sports drink COIS- C.A.H. received honoraria for serving on the Science Advisory Board for EAS from 2013 to 2015 and from Abbott Nutrition for providing a lecture for one webinar lecture in 2022. No other conflict exist. The funding agency had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. EDAT- 2023/11/25 12:44 MHDA- 2023/11/27 16:18 PMCR- 2023/11/12 CRDT- 2023/11/25 01:20 PHST- 2023/10/05 00:00 [received] PHST- 2023/10/23 00:00 [revised] PHST- 2023/11/10 00:00 [accepted] PHST- 2023/11/27 16:18 [medline] PHST- 2023/11/25 12:44 [pubmed] PHST- 2023/11/25 01:20 [entrez] PHST- 2023/11/12 00:00 [pmc-release] AID - nu15224759 [pii] AID - nutrients-15-04759 [pii] AID - 10.3390/nu15224759 [doi] PST - epublish SO - Nutrients. 2023 Nov 12;15(22):4759. doi: 10.3390/nu15224759.