PMID- 38006289
OWN - NLM
STAT- MEDLINE
DCOM- 20240123
LR  - 20240202
IS  - 1939-1676 (Electronic)
IS  - 0891-6640 (Print)
IS  - 0891-6640 (Linking)
VI  - 38
IP  - 1
DP  - 2024 Jan-Feb
TI  - Prevalence of nonconvulsive seizures and nonconvulsive status epilepticus in dogs 
      and cats with a history of cluster seizures: A retrospective study.
PG  - 238-246
LID - 10.1111/jvim.16953 [doi]
AB  - BACKGROUND: Nonconvulsive seizures (NCS) and nonconvulsive status epilepticus 
      (NCSE) are frequently observed in human patients. Diagnosis of NCS and NCSE only 
      can be achieved by the use of electroencephalography (EEG). 
      Electroencephalographic monitoring is rare in veterinary medicine and 
      consequently there is limited data on frequency of NCS and NCSE. OBJECTIVES: 
      Determine the prevalence of NCS and NCSE in dogs and cats with a history of 
      cluster seizures. ANIMALS: Twenty-six dogs and 12 cats. METHODS: Retrospective 
      study. Medical records of dogs and cats with cluster seizures were reviewed. 
      Electroencephalography was performed in order to identify electrographic seizure 
      activity after the apparent cessation of convulsive seizure activity. RESULTS: 
      Nonconvulsive seizures were detected in 9 dogs and 2 cats out of the 38 patients 
      (29%). Nonconvulsive status epilepticus was detected in 4 dogs and 2 cats (16%). 
      Five patients had both NCS and NCSE. A decreased level of consciousness was 
      evident in 6/11 patients with NCS, 3/6 also had NCSE. Mortality rate for patients 
      with NCS (73%) and NCSE (67%) was much higher than that for patients with no 
      seizure activity on EEG (27%). CONCLUSION AND CLINICAL IMPORTANCE: Prevalence of 
      NCS and NCSE is high in dogs and cats with a history of cluster seizures. 
      Nonconvulsive seizures and NCSE are difficult to detect clinically and are 
      associated with higher in hospital mortality rates. Results indicate that prompt 
      EEG monitoring should be performed in dogs and cats with cluster seizures.
CI  - (c) 2023 The Authors. Journal of Veterinary Internal Medicine published by Wiley 
      Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
FAU - Tastensen, Carina
AU  - Tastensen C
AUID- ORCID: 0009-0004-6289-8343
AD  - Department for Small Animals, Leipzig University, Leipzig, Germany.
FAU - Gutmann, Sarah
AU  - Gutmann S
AUID- ORCID: 0000-0002-8909-8205
AD  - Department for Small Animals, Leipzig University, Leipzig, Germany.
FAU - Loderstedt, Shenja
AU  - Loderstedt S
AUID- ORCID: 0000-0001-9987-5349
AD  - Department for Small Animals, Leipzig University, Leipzig, Germany.
FAU - Flegel, Thomas
AU  - Flegel T
AUID- ORCID: 0000-0001-9892-0224
AD  - Department for Small Animals, Leipzig University, Leipzig, Germany.
FAU - Demeny, Helga
AU  - Demeny H
AUID- ORCID: 0000-0002-8620-1721
AD  - Demed-Veterinary Neurology, Cluj-Napoca, Romania.
FAU - Baum, Petra
AU  - Baum P
AD  - Department of Neurology, Leipzig University, Leipzig, Germany.
LA  - eng
GR  - Open Access Publishing Fund of Leipzig University/
PT  - Journal Article
DEP - 20231125
PL  - United States
TA  - J Vet Intern Med
JT  - Journal of veterinary internal medicine
JID - 8708660
SB  - IM
MH  - Humans
MH  - Cats
MH  - Dogs
MH  - Animals
MH  - Retrospective Studies
MH  - Prevalence
MH  - *Cat Diseases/epidemiology
MH  - *Dog Diseases/epidemiology
MH  - Seizures/epidemiology/veterinary
MH  - *Status Epilepticus/epidemiology/veterinary
MH  - Electroencephalography/veterinary/methods
PMC - PMC10800195
OTO - NOTNLM
OT  - burst-suppression pattern (BSP)
OT  - electroencephalography (EEG)
OT  - electrographic seizure
OT  - wireless video-EEG
COIS- Authors declare no conflict of interest.
EDAT- 2023/11/26 07:42
MHDA- 2024/01/23 06:44
PMCR- 2023/11/25
CRDT- 2023/11/25 06:34
PHST- 2023/06/30 00:00 [received]
PHST- 2023/11/13 00:00 [accepted]
PHST- 2024/01/23 06:44 [medline]
PHST- 2023/11/26 07:42 [pubmed]
PHST- 2023/11/25 06:34 [entrez]
PHST- 2023/11/25 00:00 [pmc-release]
AID - JVIM16953 [pii]
AID - 10.1111/jvim.16953 [doi]
PST - ppublish
SO  - J Vet Intern Med. 2024 Jan-Feb;38(1):238-246. doi: 10.1111/jvim.16953. Epub 2023 
      Nov 25.