PMID- 38008447
OWN - NLM
STAT- Publisher
LR  - 20231126
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
DP  - 2023 Nov 27
TI  - Multiple Gastric Neuroendocrine Tumors Associated with Long-term Use of a Proton 
      Pump Inhibitor and a Potassium-competitive Acid Blocker.
LID - 10.2169/internalmedicine.2857-23 [doi]
AB  - A 52-year-old man who had been using a proton pump inhibitor (PPI) and a 
      potassium-competitive acid blocker (P-CAB) for 14 years underwent 
      esophagogastroduodenoscopy and was found to have three neuroendocrine tumors 
      (NETs) in the gastric body. Following detailed examinations, parietal cell 
      dysfunction was excluded, and the NETs did not meet the criteria for the Rindi 
      classification types I-III. The lesions were ultimately considered to be 
      associated with the long-term use of the PPI and P-CAB. We performed endoscopic 
      submucosal dissection of the lesions, with no recurrence or new lesions noted 
      after discontinuation of the PPI and P-CAB.
FAU - Nagao, Soichiro
AU  - Nagao S
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Yabuuchi, Yohei
AU  - Yabuuchi Y
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Tanaka, Kosuke
AU  - Tanaka K
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Morihisa, Yoshiki
AU  - Morihisa Y
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Kobayashi, Takuya
AU  - Kobayashi T
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Akiyama, Shinsuke
AU  - Akiyama S
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Tanke, Gensho
AU  - Tanke G
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Wada, Masaya
AU  - Wada M
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Morita, Shuko
AU  - Morita S
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Inoue, Satoko
AU  - Inoue S
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Tei, Hiroshi
AU  - Tei H
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
FAU - Yamashita, Daisuke
AU  - Yamashita D
AD  - Department of Pathology, Kobe City Medical Center General Hospital, Japan.
FAU - Inokuma, Tetsuro
AU  - Inokuma T
AD  - Department of Gastroenterology, Kobe City Medical Center General Hospital, Japan.
LA  - eng
PT  - Journal Article
DEP - 20231127
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
OTO - NOTNLM
OT  - hypergastrinemia
OT  - neuroendocrine tumor
OT  - potassium-competitive acid blocker
OT  - proton pump inhibitor
EDAT- 2023/11/27 00:43
MHDA- 2023/11/27 00:43
CRDT- 2023/11/26 20:43
PHST- 2023/11/27 00:43 [medline]
PHST- 2023/11/27 00:43 [pubmed]
PHST- 2023/11/26 20:43 [entrez]
AID - 10.2169/internalmedicine.2857-23 [doi]
PST - aheadofprint
SO  - Intern Med. 2023 Nov 27. doi: 10.2169/internalmedicine.2857-23.