PMID- 38015070
OWN - NLM
STAT- MEDLINE
DCOM- 20240321
LR  - 20240321
IS  - 1557-0584 (Electronic)
IS  - 1557-0576 (Linking)
VI  - 48
IP  - 2
DP  - 2024 Apr 1
TI  - Reliability and Minimal Detectable Change for Respiratory Muscle Strength 
      Measures in Individuals With Multiple Sclerosis.
PG  - 94-101
LID - 10.1097/NPT.0000000000000462 [doi]
AB  - BACKGROUND AND PURPOSE: The test-retest reliability and minimal detectable 
      changes (MDCs) for respiratory muscle strength measures have not been determined 
      in individuals with multiple sclerosis (MS). This study determined the 
      test-retest reliability and MDCs for specific respiratory muscle strength 
      measures, as well as their associations with health-related quality of life 
      (HRQoL), disability, dyspnea, and physical activity level measures in this 
      population. In addition, the study examined differences in respiratory muscle 
      strength between different degrees of disability. METHODS: Sixty-one individuals 
      with MS attended 2 appointments separated by 7 to 10 days. Respiratory muscle 
      strength was evaluated by maximal inspiratory and expiratory pressures (MIP/MEP), 
      HRQoL by EuroQol-5D-5L (index and visual analog scale [EQ-VAS]), disability by 
      the Expanded Disability Status Scale, dyspnea by the Medical Research Council 
      scale, and physical activity levels by the International Physical Activity 
      Questionnaire. RESULTS: Respiratory muscle strength measures had excellent 
      test-retest reliability (ICC >/= 0.92). The MDC for MIP is 15.42 cmH 2 O and for 
      MEP is 17.84 cmH 2 O. Participants with higher respiratory muscle strength 
      (MIP/MEP cmH 2 O and percentage of predicted values) had higher HRQoL ( r = 
      0.54-0.62, P < 0.01, EQ-5D-5L index; r = 0.30-0.42, P < 0.05, EQ-VAS); those with 
      higher expiratory muscle strength (cmH 2 O and percentage of predicted values) 
      had lower levels of disability ( r </= -0.66) and dyspnea ( r </= -0.61). There were 
      differences in respiratory muscle strength between different degrees of 
      disability ( P < 0.01; d >/= 0.73). DISCUSSION AND CONCLUSION: Respiratory muscle 
      strength measures provide excellent test-retest reliability in individuals with 
      MS. MDCs can be interpreted and applied in the clinical setting. Low respiratory 
      muscle strength can contribute to a poor HRQoL; specifically, expiratory muscle 
      strength appears to have the strongest influence on disability status and 
      dyspnea.
CI  - Copyright (c) 2024 Academy of Neurologic Physical Therapy, APTA.
FAU - Aguilar-Zafra, Sandra
AU  - Aguilar-Zafra S
AD  - Departamento de Fisioterapia, Facultad de Ciencias de la Salud, Motion in Brains 
      Research Group, Centro Superior de Estudios Universitarios La Salle, Universidad 
      Autonoma de Madrid, Spain, and Texum S.L. Physiotherapy Center, Coslada, Madrid, 
      Spain (S.A.Z.); Department of Radiology, Rehabilitation and Physiotherapy, 
      Faculty of Nursing, Physiotherapy and Podiatry, Complutense University of Madrid, 
      Madrid, Spain (R.F.G.); and Department of Radiology, Rehabilitation and 
      Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, Universidad 
      Complutense de Madrid, IdISSC, Madrid, Spain (T.d.C., I.L.d.U.V.).
FAU - Fabero-Garrido, Raul
AU  - Fabero-Garrido R
FAU - Del Corral, Tamara
AU  - Del Corral T
FAU - Lopez-de-Uralde-Villanueva, Ibai
AU  - Lopez-de-Uralde-Villanueva I
LA  - eng
PT  - Journal Article
DEP - 20231124
PL  - United States
TA  - J Neurol Phys Ther
JT  - Journal of neurologic physical therapy : JNPT
JID - 101193365
SB  - IM
MH  - Humans
MH  - *Quality of Life
MH  - *Multiple Sclerosis
MH  - Reproducibility of Results
MH  - Muscle Strength/physiology
MH  - Dyspnea
MH  - Respiratory Muscles/physiology
COIS- The authors declare no conflict of interest.
EDAT- 2023/11/28 12:41
MHDA- 2024/03/21 12:48
CRDT- 2023/11/28 09:54
PHST- 2024/03/21 12:48 [medline]
PHST- 2023/11/28 12:41 [pubmed]
PHST- 2023/11/28 09:54 [entrez]
AID - 01253086-990000000-00051 [pii]
AID - 10.1097/NPT.0000000000000462 [doi]
PST - ppublish
SO  - J Neurol Phys Ther. 2024 Apr 1;48(2):94-101. doi: 10.1097/NPT.0000000000000462. 
      Epub 2023 Nov 24.