PMID- 38016743 OWN - NLM STAT- MEDLINE DCOM- 20231130 LR - 20231216 IS - 1658-3175 (Electronic) IS - 0379-5284 (Print) IS - 0379-5284 (Linking) VI - 44 IP - 12 DP - 2023 Dec TI - Impact of left atrial diameter on all-cause mortality of patients with STEMI undergoing primary percutaneous coronary intervention. PG - 1260-1268 LID - 10.15537/smj.2023.44.12.20230235 [doi] AB - OBJECTIVES: To evaluating the predictive significance of the left atrial diameter in acute ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). METHODS: The STEMI population came from 2 retrospective cohorts with 1097 patients, cohorts A (YongChuan Hospital) and cohorts B (Taizhou First People's Hospital). Within 3 days (cohort A) or 5 days (cohort B) post-PCI, patients underwent ultrasound evaluations. Cohort A was segmented into quartile categories based on eft atrial diameter (LAd) (Q1 to Q4). The odds ratios (ORs) for overall mortality were assessed using logistic regression. Cohort B was used for sensitivity analysis. RESULTS: During follow-up period, 226 (20.6%) patients experienced endpoint. In cohort A, univariable odds ratios were 2.68 (95%CI 1.11~6.89), 5.32 (95%CI 2.46~12.83) and 11.92 (95%CI 5.78~27.92), while multivariate ORs were 2.25 (95%CI 0.82~6.55), 5.09 (95%CI 2.12~13.56), and 15.05 (95%CI 6.58~39.09) in Q2 to Q4 group, respectively, compared with Q1 group (p for trend <0.001). Upon subgroup evaluation, the correlation between LAd and the likelihood of overall mortality was more pronounced in patients having a left ventricular ejection fraction (LVEF) between 40% and 50%, and those with LVEF >/=50%, in contrast to those with LVEF <40% (p for interaction <0.001). CONCLUSION: Left atrial diameter is indicative of the long-term overall mortality risk in STEMI patients post-PCI, particularly in those with an LVEF >/= 40%. CI - Copyright: (c) Saudi Medical Journal. FAU - Wang, Kai AU - Wang K AD - From the Department of Cardiology (Wang, Zeng, Chen), Yongchuan Hospital of Chongqing Medical University; and form the Department of Cardiology (Chen, Yu), The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. FAU - Zeng, Deli AU - Zeng D AD - From the Department of Cardiology (Wang, Zeng, Chen), Yongchuan Hospital of Chongqing Medical University; and form the Department of Cardiology (Chen, Yu), The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. FAU - Chen, Zijun AU - Chen Z AD - From the Department of Cardiology (Wang, Zeng, Chen), Yongchuan Hospital of Chongqing Medical University; and form the Department of Cardiology (Chen, Yu), The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. FAU - Yu, Wei AU - Yu W AUID- ORCID: 0009-0007-4795-4732 AD - From the Department of Cardiology (Wang, Zeng, Chen), Yongchuan Hospital of Chongqing Medical University; and form the Department of Cardiology (Chen, Yu), The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. LA - eng PT - Journal Article PL - Saudi Arabia TA - Saudi Med J JT - Saudi medical journal JID - 7909441 SB - IM MH - Humans MH - *ST Elevation Myocardial Infarction/surgery MH - *Percutaneous Coronary Intervention/adverse effects MH - Stroke Volume MH - Retrospective Studies MH - Ventricular Function, Left MH - *Atrial Fibrillation MH - Treatment Outcome PMC - PMC10712788 OTO - NOTNLM OT - heart atrial OT - mortality OT - myocardial infarction OT - prognosis EDAT- 2023/11/29 00:42 MHDA- 2023/11/30 06:43 PMCR- 2023/12/01 CRDT- 2023/11/28 20:43 PHST- 2023/08/14 00:00 [received] PHST- 2023/10/17 00:00 [accepted] PHST- 2023/11/30 06:43 [medline] PHST- 2023/11/29 00:42 [pubmed] PHST- 2023/11/28 20:43 [entrez] PHST- 2023/12/01 00:00 [pmc-release] AID - 44/12/1260 [pii] AID - SaudiMedJ-44-12-1260 [pii] AID - 10.15537/smj.2023.44.12.20230235 [doi] PST - ppublish SO - Saudi Med J. 2023 Dec;44(12):1260-1268. doi: 10.15537/smj.2023.44.12.20230235.