PMID- 38025927
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231201
IS  - 2090-004X (Print)
IS  - 2090-0058 (Electronic)
IS  - 2090-004X (Linking)
VI  - 2023
DP  - 2023
TI  - A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan.
PG  - 9647418
LID - 10.1155/2023/9647418 [doi]
LID - 9647418
AB  - In this study, we reported the patterns, epidemiology, and clinical features of 
      anterior uveitis (AU) in Taiwan, an area of Eastern Asia. This prospective, 
      cross-sectional case series study was performed to identify patients with AU at 
      two tertiary medical centers (Kaohsiung Chang Gung Memorial Hospital and 
      Kaohsiung Veterans General Hospital) located at the southern Taiwan between 
      December 1, 2018, and March 31, 2020. The clinical diagnoses, ocular 
      presentations, and laboratory data, including the results of the aqueous 
      polymerase chain reaction tests, were investigated in these patients. A total of 
      112 patients, with a mean age of 48.9 years, were included. Most patients (87.5%) 
      presented with unilateral eye disease, with 30 cases of ocular hypertension at 
      the first presentation (27%). The most common clinical diagnoses were idiopathic 
      AU (37.5%), human leukocyte antigen (HLA)-B27-associated acute AU (25.0%), and 
      herpetic AU (18.8%). Among patients with herpetic AU, cytomegalovirus (CMV) was 
      the most common pathogen (17/21, 81%). Compared to HLA-B27-associated acute AU, 
      CMV-related AU was mostly observed in patients that were older in age, exhibited 
      higher intraocular pressure, more keratic precipitates, greater iris atrophy, and 
      more pseudophakia, but was least reported in those with posterior synechiae. This 
      prospective study identified the pattern and clinical features of AU in southern 
      Taiwan.
CI  - Copyright (c) 2023 Wei-Yu Chiang et al.
FAU - Chiang, Wei-Yu
AU  - Chiang WY
AUID- ORCID: 0000-0002-0791-8303
AD  - Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang 
      Gung University College of Medicine, Kaohsiung City 83301, Taiwan.
AD  - School of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan.
FAU - Chen, Shih-Chou
AU  - Chen SC
AUID- ORCID: 0000-0001-8333-1478
AD  - Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, 
      Taiwan.
FAU - Sheu, Shwu-Jiuan
AU  - Sheu SJ
AUID- ORCID: 0000-0003-2644-2475
AD  - Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung, 
      Taiwan.
AD  - Kaohsiung Medical University, Kaohsiung, Taiwan.
FAU - Kuo, Hsi-Kung
AU  - Kuo HK
AUID- ORCID: 0000-0001-6810-0057
AD  - Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang 
      Gung University College of Medicine, Kaohsiung City 83301, Taiwan.
AD  - School of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20231107
PL  - United States
TA  - J Ophthalmol
JT  - Journal of ophthalmology
JID - 101524199
PMC - PMC10645496
COIS- The authors declare that there are no conflicts of interest.
EDAT- 2023/11/29 18:41
MHDA- 2023/11/29 18:42
PMCR- 2023/11/07
CRDT- 2023/11/29 16:40
PHST- 2022/08/17 00:00 [received]
PHST- 2023/05/25 00:00 [revised]
PHST- 2023/10/14 00:00 [accepted]
PHST- 2023/11/29 18:42 [medline]
PHST- 2023/11/29 18:41 [pubmed]
PHST- 2023/11/29 16:40 [entrez]
PHST- 2023/11/07 00:00 [pmc-release]
AID - 10.1155/2023/9647418 [doi]
PST - epublish
SO  - J Ophthalmol. 2023 Nov 7;2023:9647418. doi: 10.1155/2023/9647418. eCollection 
      2023.