PMID- 38028529
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231201
IS  - 2222-3959 (Print)
IS  - 2227-4898 (Electronic)
IS  - 2222-3959 (Linking)
VI  - 16
IP  - 11
DP  - 2023
TI  - Choroidal thickness measurements in young Saudi adult population: a 
      cross-sectional study.
PG  - 1814-1819
LID - 10.18240/ijo.2023.11.12 [doi]
AB  - AIM: To determine the choroidal thickness (CT) in young healthy Saudi adults 
      using spectral-domain optical coherence tomography (SD-OCT) with an automated CT 
      segmentation software. METHODS: Fifty-eight young adults (total of 116 eyes), 39 
      males and 19 females participated in this study between the ages of 18 and 38y 
      (mean 22.65+/-3.9y). All participants underwent ophthalmic screening examination, 
      including the SD-OCT for measurements of CT in each quadrant egmented into five 
      eccentric regions starting from the foveal region up to 4.5 mm towards the 
      periphery. RESULTS: The choroid was thickest in the foveal region (central 1 mm, 
      300+/-60 microm) and began to progressively thinner beyond the parafovea (1.5-2.5 mm, 
      284+/-67 microm) towards the peripheral region (3.5-4.5 mm from the fovea, 254+/-83 microm). 
      The superior choroid showed the thickest profile (309+/-57 microm), while the nasal 
      choroid exhibited the thinnest (229+/-76 microm). The rate of the thinning with 
      increasing eccentricity was more predominant in the nasal choroid, which thinned 
      from the foveal region (294+/-58 microm) to the peripheral region (158+/-55 microm). The 
      superior and inferior choroid did not show a statistically significant thinning 
      with eccentricity (all P>0.05). There was no statistically significant difference 
      in the CT between gender, age, and laterality of the eyes (all P>0.05). A 
      significant association of myopia with thinner subfoveal choroid was observed 
      (Pearson's, r=0.37), and regression analysis showed that a 10.3 microm choroidal 
      thinning for each diopter increase of myopia. CONCLUSION: CT profile depends on 
      eccentric and the quadrant. The CT profile across the measured area in the young 
      Saudi adult population is comparable to other previous reports. Refractive error 
      is critical for CT evaluation.
CI  - International Journal of Ophthalmology Press.
FAU - Althomali, Mohammed M
AU  - Althomali MM
AD  - Optometry Department, College of Applied Medical Sciences, King Saud University, 
      Riyadh 11362, Saudi Arabia.
FAU - Alharbi, Ahmed A
AU  - Alharbi AA
AD  - Optometry Department, College of Applied Medical Sciences, King Saud University, 
      Riyadh 11362, Saudi Arabia.
FAU - Albnayan, Nouf M
AU  - Albnayan NM
AD  - Optometry Department, College of Applied Medical Sciences, King Saud University, 
      Riyadh 11362, Saudi Arabia.
FAU - Alkhudhair, Abdulaziz M
AU  - Alkhudhair AM
AD  - Optometry Department, College of Applied Medical Sciences, King Saud University, 
      Riyadh 11362, Saudi Arabia.
FAU - Alanazi, Muteb K
AU  - Alanazi MK
AD  - Optometry Department, College of Applied Medical Sciences, King Saud University, 
      Riyadh 11362, Saudi Arabia.
LA  - eng
PT  - Journal Article
DEP - 20231118
PL  - China
TA  - Int J Ophthalmol
JT  - International journal of ophthalmology
JID - 101553860
PMC - PMC10626366
OTO - NOTNLM
OT  - Saudi population
OT  - choroidal thickness
OT  - optical coherence tomography
OT  - young adults
EDAT- 2023/11/29 18:43
MHDA- 2023/11/29 18:44
PMCR- 2023/11/18
CRDT- 2023/11/29 17:14
PHST- 2022/11/17 00:00 [received]
PHST- 2023/08/09 00:00 [accepted]
PHST- 2023/11/29 18:44 [medline]
PHST- 2023/11/29 18:43 [pubmed]
PHST- 2023/11/29 17:14 [entrez]
PHST- 2023/11/18 00:00 [pmc-release]
AID - ijo-16-11-1814 [pii]
AID - 10.18240/ijo.2023.11.12 [doi]
PST - epublish
SO  - Int J Ophthalmol. 2023 Nov 18;16(11):1814-1819. doi: 10.18240/ijo.2023.11.12. 
      eCollection 2023.