PMID- 38030389
OWN - NLM
STAT- MEDLINE
DCOM- 20240520
LR  - 20240520
IS  - 2542-5641 (Electronic)
IS  - 0366-6999 (Print)
IS  - 0366-6999 (Linking)
VI  - 137
IP  - 10
DP  - 2024 May 20
TI  - Strategy and technique for surgical treatment of Ebstein's anomaly.
PG  - 1218-1224
LID - 10.1097/CM9.0000000000002854 [doi]
AB  - BACKGROUND: Ebstein's anomaly (EA) is a rare and complex congenital heart 
      anomaly, and the effect of surgical treatment is not ideal. This study aims to 
      introduce our experience in management strategies, surgical techniques, and 
      operative indications for patients with Ebstein's anomaly. METHODS: A 
      retrospective study of 258 operations was performed in 253 patients by the same 
      cardiac surgeon in The First Hospital of Tsinghua University between March 2004 
      and January 2020. 32 patients had previously received cardiac surgery in other 
      hospitals. The clinical data including diagnosis, operative indications, 
      techniques, pathological changes, and survival rates were collected and analyzed. 
      RESULTS: Anatomical correction was performed in 203 (78.7%) operations, 1(1/2) 
      ventricle repair in 38 (14.7%) operations, tricuspid valve repair only in four 
      operations (1.6%), tricuspid valve replacement in ten (3.9%), total cavopulmonary 
      connection (TCPC) in two (0.8%), and Glenn operation in one operation (0.4%). 
      Reoperation was performed in five patients (2.0%) during hospitalization. Among 
      them, tricuspid valve replacement was performed in one patient, 1(1/2) ventricle 
      repair in two patients, and tricuspid valve annulus reinforcement in two 
      patients. Five patients died with an early mortality rate of 2.0%. Complete 
      atrioventricular conduction block was complicated in one patient (0.4%). A total 
      of 244 patients was followed up (four in the 253 patients lost) with a duration 
      of 3.0-168.0 (87.6 +/- 38.4) months. Cardiac function of 244 patients improved 
      significantly with mean New York Heart Association (NYHA) functional class 
      recovery from 3.5 to 1.1. The mean grade of tricuspid valve regurgitation 
      improved from 3.6 to 1.5. Three late deaths (1.2%) occurred. The survival rates 
      at five and ten years after surgery were 98.6% and 98.2%, respectively. 
      Reoperation was performed in five patients (2.0%) during the follow-up period. 
      CONCLUSION: Based on our management strategies and operative principles and 
      techniques, anatomical correction of EA is capable of achieving excellent 
      long-term results, and low rates of TCPC, 1(1/2) ventricle repair and valvular 
      replacement.
CI  - Copyright (c) 2024 The Chinese Medical Association, produced by Wolters Kluwer, 
      Inc. under the CC-BY-NC-ND license.
FAU - Wu, Qingyu
AU  - Wu Q
AD  - Cardiac Center, Division of Cardiac Surgery, The First Hospital of Tsinghua 
      University, Beijing 100016, China.
FAU - Zhang, Xiaoya
AU  - Zhang X
FAU - Zhang, Mingkui
AU  - Zhang M
FAU - Li, Hongyin
AU  - Li H
FAU - Zhang, Dongya
AU  - Zhang D
FAU - Wang, Lianyi
AU  - Wang L
FAU - Wu, Qingfeng
AU  - Wu Q
LA  - eng
PT  - Journal Article
DEP - 20231128
PL  - China
TA  - Chin Med J (Engl)
JT  - Chinese medical journal
JID - 7513795
SB  - IM
MH  - Humans
MH  - *Ebstein Anomaly/surgery
MH  - Retrospective Studies
MH  - Male
MH  - Female
MH  - Adult
MH  - Adolescent
MH  - Child
MH  - Young Adult
MH  - Child, Preschool
MH  - *Tricuspid Valve/surgery
MH  - Infant
MH  - Middle Aged
MH  - Cardiac Surgical Procedures/methods
PMC - PMC11101237
COIS- None.
EDAT- 2023/11/30 00:43
MHDA- 2024/05/20 06:42
PMCR- 2024/05/20
CRDT- 2023/11/29 21:38
PHST- 2023/05/31 00:00 [received]
PHST- 2024/05/20 00:00 [pmc-release]
PHST- 2024/05/20 06:42 [medline]
PHST- 2023/11/30 00:43 [pubmed]
PHST- 2023/11/29 21:38 [entrez]
AID - 00029330-990000000-00872 [pii]
AID - CMJ-2023-215 [pii]
AID - 10.1097/CM9.0000000000002854 [doi]
PST - ppublish
SO  - Chin Med J (Engl). 2024 May 20;137(10):1218-1224. doi: 
      10.1097/CM9.0000000000002854. Epub 2023 Nov 28.