PMID- 38034523
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231202
IS  - 2236-1960 (Print)
IS  - 2236-1960 (Electronic)
IS  - 2236-1960 (Linking)
VI  - 13
DP  - 2023
TI  - Alcoholic foamy degeneration: an unusual presentation of the alcoholic liver 
      disease diagnosed on autopsy.
PG  - e2023446
LID - 10.4322/acr.2023.446 [doi]
LID - e2023446
AB  - Alcoholic foamy degeneration (AFD) is an uncommon presentation of alcoholic liver 
      disease (ALD) with characteristic histologic findings of foamy-looking 
      hepatocytes due to the presence of abundant microvesicles of fat within the 
      cytoplasm predominantly in perivenular and midzonal regions without inflammation 
      and fibrosis. It is underdiagnosed as the patients quickly recover after 
      alcoholic abstinence and are rarely caught on biopsies. AFD has better prognosis 
      than alcoholic hepatitis, and the injury mechanism is different, warranting a 
      different diagnosis. We present an uncommon case of AFD incidentally diagnosed 
      during autopsy in a chronic alcoholic and diabetic man.
CI  - Copyright: (c) 2023 The Authors.
FAU - Joshi, Rashmi
AU  - Joshi R
AUID- ORCID: 0000-0003-1807-7674
AD  - Post Graduate Institute of Medical Education and Research, Department of 
      Histopathology, Chandigarh, India.
FAU - Parkhi, Mayur
AU  - Parkhi M
AUID- ORCID: 0000-0002-6040-6737
AD  - Post Graduate Institute of Medical Education and Research, Department of 
      Histopathology, Chandigarh, India.
FAU - Gupta, Anjali
AU  - Gupta A
AUID- ORCID: 0000-0001-9219-7178
AD  - Post Graduate Institute of Medical Education and Research, Department of 
      Histopathology, Chandigarh, India.
FAU - Susngi, Terence
AU  - Susngi T
AUID- ORCID: 0009-0005-3470-6313
AD  - Post Graduate Institute of Medical Education and Research, Department of Internal 
      Medicine, Chandigarh, India.
FAU - Kumar, Ashwani
AU  - Kumar A
AUID- ORCID: 0000-0002-0086-7398
AD  - Post Graduate Institute of Medical Education and Research, Department of 
      Histopathology, Chandigarh, India.
FAU - Dhibar, Deba Prasad
AU  - Dhibar DP
AUID- ORCID: 0000-0002-0201-0160
AD  - Post Graduate Institute of Medical Education and Research, Department of Internal 
      Medicine, Chandigarh, India.
FAU - Mitra, Suvradeep
AU  - Mitra S
AUID- ORCID: 0000-0002-5520-8306
AD  - Post Graduate Institute of Medical Education and Research, Department of 
      Histopathology, Chandigarh, India.
LA  - eng
PT  - Case Reports
DEP - 20231011
PL  - Brazil
TA  - Autops Case Rep
JT  - Autopsy & case reports
JID - 101640070
PMC - PMC10688259
OTO - NOTNLM
OT  - Autopsy
OT  - Liver Diseases, Alcoholic
OT  - Pancreatitis, Acute Necrotizing
COIS- Conflict of interest: None.
EDAT- 2023/11/30 18:45
MHDA- 2023/11/30 18:46
PMCR- 2023/10/11
CRDT- 2023/11/30 17:34
PHST- 2023/06/19 00:00 [received]
PHST- 2023/08/14 00:00 [accepted]
PHST- 2023/11/30 18:46 [medline]
PHST- 2023/11/30 18:45 [pubmed]
PHST- 2023/11/30 17:34 [entrez]
PHST- 2023/10/11 00:00 [pmc-release]
AID - acrep177023_EN [pii]
AID - 10.4322/acr.2023.446 [doi]
PST - epublish
SO  - Autops Case Rep. 2023 Oct 11;13:e2023446. doi: 10.4322/acr.2023.446. eCollection 
      2023.