PMID- 38043082
OWN - NLM
STAT- MEDLINE
DCOM- 20231219
LR  - 20231219
IS  - 1734-154X (Electronic)
IS  - 0001-527X (Linking)
VI  - 70
IP  - 4
DP  - 2023 Dec 3
TI  - Relationship between chemical industrial environment and allergic skin diseases.
PG  - 899-904
LID - 10.18388/abp.2020_6797 [doi]
AB  - OBJECTIVE: This study is an exploration of the relationship between chemical 
      industrial environment and allergic skin diseases. METHODS: In this retrospective 
      analysis, 200 patients with allergic skin diseases who worked or lived in a 
      chemical industrial zone and were admitted in our hospital between January 2018 
      and January 2020 were enrolled as Group A. Besides, 500 patients with allergic 
      skin disease who lived in Zhenhai New District, five kilometers away from the 
      chemical radiation zone, were selected as Group B. The specific immunoglobulin E 
      (IgE) levels were determined by Western blotting. The allergen positivity, as 
      well as allergen positivity between different age, sex and body mass index (BMI) 
      were compared between the two groups. The positive food-specific allergen IgE 
      antibody (sIgE) and positive inhalational sIgE were compared between the two 
      groups. RESULTS: The positive rate of total IgE and inhalational sIgE in Group A 
      was higher than that in Group B (P<0.05), while there was no significant 
      difference in positive rate in food sIgE between the two groups (P>0.05). In 
      Group A, the differences in positive rates of total IgE, food-induced sIgE and 
      inhalational sIgE were not significant between patients with different ages, 
      sexes and BMI (P>0.05). There was no significant difference between the two 
      groups in sIgE positive rates of wheat, mango, soybean/peanut/cashew nut 
      combination, limb/beef combination, crab/shrimp/fish combination, milk and egg 
      white (P>0.05). The positive rates of inhalational sIgE in tree combination and 
      dust mites/household dust mites combination in Group A were higher than those in 
      Group B (P<0.05), but had no significant difference between the two groups in the 
      positive rates of inhalational sIgE in Humulus japonicus, mold combination 1, 
      cockroach, cat/dog hair combination, and ragweed/artemisia combination (P>0.05). 
      CONCLUSION: Chemical industrial environment is closely associated with allergic 
      dermatosis, and the positive rate of total IgE and inhalational sIgE increases 
      significantly in patients living there.
FAU - Fu, Shaohua
AU  - Fu S
AD  - Clinical Laboratory, Ningbo Zhenhai People's Hospital (Ningbo No.7 Hospital), 
      Ningbo, Zhejiang Province, China.
FAU - Gong, Minli
AU  - Gong M
AD  - Clinical Laboratory, Ningbo Zhenhai People's Hospital (Ningbo No.7 Hospital), 
      Ningbo, Zhejiang Province, China.
FAU - Xing, Guisheng
AU  - Xing G
AD  - Department of Medical, Ningbo Zhenhai People's Hospital (Ningbo No.7 Hospital), 
      Ningbo, Zhejiang Province, China.
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Acta Biochim Pol
JT  - Acta biochimica Polonica
JID - 14520300R
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 0 (Dust)
SB  - IM
MH  - Animals
MH  - Dogs
MH  - Cattle
MH  - Humans
MH  - Retrospective Studies
MH  - Skin Tests
MH  - *Allergens
MH  - *Dermatitis, Atopic/etiology
MH  - Immunoglobulin E
MH  - Dust
EDAT- 2023/12/03 18:41
MHDA- 2023/12/19 06:41
CRDT- 2023/12/03 15:07
PHST- 2023/04/11 00:00 [received]
PHST- 2023/10/17 00:00 [accepted]
PHST- 2023/12/19 06:41 [medline]
PHST- 2023/12/03 18:41 [pubmed]
PHST- 2023/12/03 15:07 [entrez]
AID - 6797 [pii]
AID - 10.18388/abp.2020_6797 [doi]
PST - ppublish
SO  - Acta Biochim Pol. 2023 Dec 3;70(4):899-904. doi: 10.18388/abp.2020_6797.