PMID- 38043902
OWN - NLM
STAT- MEDLINE
DCOM- 20240220
LR  - 20240226
IS  - 1879-0887 (Electronic)
IS  - 0167-8140 (Linking)
VI  - 190
DP  - 2024 Jan
TI  - Recommendation on the technical and dosimetric data to be included in 
      stereotactic body radiation therapy clinical trial publications based on a 
      systematic review.
PG  - 110042
LID - S0167-8140(23)09349-0 [pii]
LID - 10.1016/j.radonc.2023.110042 [doi]
AB  - The results of phase II and III trials on Stereotactic Body Radiation Therapy 
      (SBRT) increased adoption of SBRT worldwide. The ability to replicate clinical 
      trial outcomes in routine practice depends on the capability to reproduce 
      technical and dosimetric procedures used in the clinical trial. In this 
      systematic review, we evaluated if peer-reviewed publications of clinical trials 
      in SBRT reported sufficient technical data to ensure safe and robust 
      implementation in real world clinics. Twenty papers were selected for inclusion, 
      and data was extracted by a working group of medical physicists created following 
      the ESTRO 2021 physics workshop. A large variability in technical and dosimetric 
      data were observed, with frequent lack of required information for reproducing 
      trial procedures. None of the evaluated studies were judged completely 
      reproducible from a technical perspective. A list of recommendations has been 
      provided by the group, based on the analysis and consensus process, to ensure an 
      adequate reproducibility of technical parameters in primary SBRT clinical trials. 
      Future publications should consider these recommendations to assist 
      transferability of the clinical trial in real world practice.
CI  - Copyright (c) 2023 Elsevier B.V. All rights reserved.
FAU - Hardcastle, Nicholas
AU  - Hardcastle N
AD  - Physical Sciences, Peter MacCallum Cancer Centre & Sir Peter MacCallum, 
      Department of Oncology, University of Melbourne, Australia.
FAU - Josipovic, Mirjana
AU  - Josipovic M
AD  - Department of Oncology, Centre for Cancer and Organ Diseases, Copenhagen 
      University Hospital - Rigshospitalet (RH), Blegdamsvej 9, 2100 Copenhagen, 
      Denmark; Department of Health and Medical Sciences, University of Copenhagen, 
      Blegdamsvej 3B, 2200 Copenhagen, Denmark.
FAU - Clementel, Enrico
AU  - Clementel E
AD  - European Organisation for the Research and Treatment of Cancer (EORTC) 
      Headquarters, Brussels, Belgium.
FAU - Hernandez, Victor
AU  - Hernandez V
AD  - Department of Medical Physics, Hospital Sant Joan de Reus, IISPV, 43204 
      Tarragona, Spain.
FAU - Smyth, Gregory
AU  - Smyth G
AD  - The London Radiotherapy Centre, HCA Healthcare UK, London, UK.
FAU - Gober, Manuela
AU  - Gober M
AD  - Department of Radiation Oncology, Medical University of Vienna, Austria.
FAU - Wilke, Lotte
AU  - Wilke L
AD  - Department of Radiation Oncology, University Hospital Zurich, 8091 Zurich, 
      Switzerland.
FAU - Eaton, David
AU  - Eaton D
AD  - Guy's and St Thomas's Hospitals, London, UK.
FAU - Josset, Stephanie
AU  - Josset S
AD  - Department of Medical Physics, Institut de Cancerologie de l'Ouest, 44805 
      Saint-Herblain, France.
FAU - Lazarakis, Smaro
AU  - Lazarakis S
AD  - Physical Sciences, Peter MacCallum Cancer Centre & Sir Peter MacCallum, 
      Department of Oncology, University of Melbourne, Australia.
FAU - Saez, Jordi
AU  - Saez J
AD  - Department of Radiation Oncology, Hospital Clinic de Barcelona, 08036 Barcelona, 
      Spain.
FAU - Vieillevigne, Laure
AU  - Vieillevigne L
AD  - Department of Medical Physics, Institut Claudius Regaud - Institut Universitaire 
      du Cancer de Toulouse, F-31059 Toulouse, France.
FAU - Jornet, Nuria
AU  - Jornet N
AD  - Servei de Radiofisica i Radioproteccio, Hospital de la Santa Creu i Sant Pau, 
      Barcelona, Spain. Electronic address: NJornet@santpau.cat.
FAU - Mancosu, Pietro
AU  - Mancosu P
AD  - Medical Physics Unit, Radiotherapy Department, IRCCS Humanitas Research Hospital, 
      Rozzano-Milano, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20231201
PL  - Ireland
TA  - Radiother Oncol
JT  - Radiotherapy and oncology : journal of the European Society for Therapeutic 
      Radiology and Oncology
JID - 8407192
SB  - IM
MH  - Humans
MH  - *Radiosurgery/methods
MH  - Reproducibility of Results
MH  - Radiometry
MH  - Radiotherapy Planning, Computer-Assisted/methods
OTO - NOTNLM
OT  - Clinical trial
OT  - Reproducibility
OT  - SBRT
OT  - Treatment planning
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/12/04 00:42
MHDA- 2024/02/20 11:50
CRDT- 2023/12/03 19:31
PHST- 2023/05/12 00:00 [received]
PHST- 2023/11/26 00:00 [revised]
PHST- 2023/11/27 00:00 [accepted]
PHST- 2024/02/20 11:50 [medline]
PHST- 2023/12/04 00:42 [pubmed]
PHST- 2023/12/03 19:31 [entrez]
AID - S0167-8140(23)09349-0 [pii]
AID - 10.1016/j.radonc.2023.110042 [doi]
PST - ppublish
SO  - Radiother Oncol. 2024 Jan;190:110042. doi: 10.1016/j.radonc.2023.110042. Epub 
      2023 Dec 1.