PMID- 38044806
OWN - NLM
STAT- MEDLINE
DCOM- 20240219
LR  - 20240219
IS  - 1440-1843 (Electronic)
IS  - 1323-7799 (Linking)
VI  - 29
IP  - 3
DP  - 2024 Mar
TI  - Effect of experimental modulation of mood on exertional dyspnoea in chronic 
      obstructive pulmonary disease.
PG  - 201-208
LID - 10.1111/resp.14642 [doi]
AB  - BACKGROUND AND OBJECTIVE: Dyspnoea is a debilitating symptom in individuals with 
      chronic obstructive pulmonary disease (COPD) and a range of other chronic 
      cardiopulmonary diseases and is often associated with anxiety and depression. The 
      present study examined the effect of visually-induced mood shifts on exertional 
      dyspnoea in individuals with COPD. METHODS: Following familiarization, 20 
      participants with mild to severe COPD (age 57-79 years) attended three 
      experimental sessions on separate days, performing two 5-min treadmill exercise 
      tests separated by a 30-min interval on each day. During each exercise test, 
      participants viewed either a positive, negative or neutral set of images sourced 
      from the International Affective Picture System (IAPS) and rated dyspnoea or leg 
      fatigue (0-10). Heart rate (HR) and peripheral oxygen saturation (SpO(2) ) were 
      measured at 1-min intervals during each test. Mood valence ratings were obtained 
      using Self-Assessment Manikin (SAM) scale (1-9). RESULTS: Mood valence ratings 
      were significantly higher when viewing positive (end-exercise 
      mean +/- SEM = 7.6 +/- 0.3) compared to negative IAPS images (2.4 +/- 0.3, p < 0.001). 
      Dyspnoea intensity (mean +/- SEM = 5.8 +/- 0.4) and dyspnoea unpleasantness 
      (5.6 +/- 0.3) when viewing negative images were significantly higher compared to 
      positive images (4.2 +/- 0.4, p = 0.004 and 3.4 +/- 0.5, p = 0.003). Eighty-five 
      percent of participants (n = 17) met the minimal clinically important difference 
      (MCID) criteria for both dyspnoea intensity and unpleasantness. HR, SpO(2) and 
      leg fatigue did not differ significantly between conditions. CONCLUSION: These 
      findings indicate that the negative affective state worsens dyspnoea in COPD, 
      thereby suggesting strategies aimed at reducing the likelihood of negative mood 
      or improving the mood may be effective in managing morbidity associated with 
      dyspnoea in COPD.
CI  - (c) 2023 The Authors. Respirology published by John Wiley & Sons Australia, Ltd on 
      behalf of Asian Pacific Society of Respirology.
FAU - Sharma, Pramod
AU  - Sharma P
AUID- ORCID: 0000-0002-5602-4496
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
AD  - The Prince Charles Hospital, Allied Health Research Collaborative, Metro North 
      Hospital and Health Service, Brisbane, Queensland, Australia.
FAU - Scheffer, Karlijn
AU  - Scheffer K
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
AD  - Department of Physiology, Radboud University Medical Center, Radboud Institute 
      for Health Sciences, Nijmegen, The Netherlands.
FAU - Louis, Menaka
AU  - Louis M
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
FAU - Aitken, Craig R
AU  - Aitken CR
AUID- ORCID: 0000-0001-9675-3549
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
AD  - The Prince Charles Hospital, Allied Health Research Collaborative, Metro North 
      Hospital and Health Service, Brisbane, Queensland, Australia.
FAU - Adams, Lewis
AU  - Adams L
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
FAU - Morris, Norman R
AU  - Morris NR
AUID- ORCID: 0000-0003-4054-4662
AD  - School of Health Sciences and Social Work, Menzies Health Institute Queensland, 
      Griffith University, Gold Coast, Queensland, Australia.
AD  - The Prince Charles Hospital, Allied Health Research Collaborative, Metro North 
      Hospital and Health Service, Brisbane, Queensland, Australia.
LA  - eng
GR  - APP597411/National Health and Medical Research Council/
PT  - Journal Article
DEP - 20231203
PL  - Australia
TA  - Respirology
JT  - Respirology (Carlton, Vic.)
JID - 9616368
SB  - IM
MH  - Humans
MH  - Middle Aged
MH  - Aged
MH  - *Quality of Life
MH  - Dyspnea/etiology
MH  - Exercise Test/methods
MH  - *Pulmonary Disease, Chronic Obstructive
MH  - Fatigue/etiology
MH  - Exercise Tolerance/physiology
OTO - NOTNLM
OT  - COPD
OT  - IAPS
OT  - chronic obstructive pulmonary disease
OT  - exertional dyspnoea
OT  - leg fatigue
OT  - mood modulation
OT  - treadmill exercise
EDAT- 2023/12/04 06:42
MHDA- 2024/02/19 06:42
CRDT- 2023/12/04 03:46
PHST- 2023/05/16 00:00 [received]
PHST- 2023/11/22 00:00 [accepted]
PHST- 2024/02/19 06:42 [medline]
PHST- 2023/12/04 06:42 [pubmed]
PHST- 2023/12/04 03:46 [entrez]
AID - 10.1111/resp.14642 [doi]
PST - ppublish
SO  - Respirology. 2024 Mar;29(3):201-208. doi: 10.1111/resp.14642. Epub 2023 Dec 3.