PMID- 38046183 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240108 IS - 2752-5457 (Electronic) IS - 2752-5457 (Linking) VI - 19 IP - 2 DP - 2023 Jul TI - Alarming Surge in Early-onset Type 2 Diabetes: A Global Catastrophe on the Horizon. PG - 7-8 LID - 10.17925/EE.2023.19.2.5 [doi] AB - Diabetes poses a significant threat to public health. In the last 30 years, the worldwide incidence of type 2 diabetes mellitus (T2DM) has increased drastically among adolescents. Since the number of young people with T2DM is rising, it is anticipated that early-onset T2DM will become a common characteristic of the diabetes population in developed and developing nations. Current evidence suggests that beta-cell function declines more rapidly in early-onset T2DM than in older-onset T2DM. In addition, early-onset T2DM appears to be associated with a greater risk of complications, comorbidities and mortality than type 1 diabetes mellitus. A stressful lifestyle, a shifted dietary habit and a lack of physical activity are cited as causes of early-onset T2DM. Early-onset T2DM is, therefore, an urgent public health concern requiring early prevention, efficient screening and prompt intervention. This article discusses the recent literature on the incidence, mortality, morbidity and risk variables of early-onset T2DM, and the current priorities and prospective directions. CI - (c) Touch Medical Media 2023. FAU - Sadat, Arefin AU - Sadat A AD - Chandpur Medical College, Chandpur, Bangladesh. LA - eng PT - Editorial DEP - 20230713 PL - England TA - touchREV Endocrinol JT - TouchREVIEWS in endocrinology JID - 101779126 PMC - PMC10688561 OTO - NOTNLM OT - Autoimmunity OT - community health OT - insulin-dependent diabetes OT - preventive medicine OT - type 2 diabetes OT - youth-onset type 2 diabetes COIS- Disclosures: Arefin Sadat has no financial or nonfinancial relationships or activities to declare in relation to this article. EDAT- 2023/12/04 06:42 MHDA- 2023/12/04 06:43 PMCR- 2023/11/01 CRDT- 2023/12/04 04:51 PHST- 2023/04/29 00:00 [received] PHST- 2023/05/31 00:00 [accepted] PHST- 2023/12/04 06:43 [medline] PHST- 2023/12/04 06:42 [pubmed] PHST- 2023/12/04 04:51 [entrez] PHST- 2023/11/01 00:00 [pmc-release] AID - 10.17925/EE.2023.19.2.5 [doi] PST - ppublish SO - touchREV Endocrinol. 2023 Jul;19(2):7-8. doi: 10.17925/EE.2023.19.2.5. Epub 2023 Jul 13.