PMID- 38054577
OWN - NLM
STAT- MEDLINE
DCOM- 20240329
LR  - 20240329
IS  - 1473-2165 (Electronic)
IS  - 1473-2130 (Linking)
VI  - 23
IP  - 4
DP  - 2024 Apr
TI  - The effect of Dendrobium officinale extract in inhibiting the senescence of 
      H(2)O(2)-induced fibroblasts based on the senescence-associated secretory 
      phenotype.
PG  - 1360-1364
LID - 10.1111/jocd.16101 [doi]
AB  - BACKGROUND: Dendrobium officinale is widely used for a long time in China, with 
      effect of antioxidation, antitumor, enhancing immunity and so on. In recent 
      years, Dendrobium officinale has been gradually used in cosmetics due to its 
      powerful beauty effects. AIMS: Based on senescence-associated secretory phenotype 
      (SASP), we studied the antiaging effect of Dendrobium officinale extract (DOE) on 
      skin. METHODS: The senescent model of human skin fibroblasts was established by 
      the induction of H(2)O(2), and the content of SASP factors was tested after the 
      treatment of DOE, such as interleukin-6 (IL-6), monocyte chemoattractant 
      protein-1 (MCP-1) and matrix metalloproteinase-1 (MMP-1). RESULTS: It was found 
      that after the treatment with different concentrations of DOE, the contents of 
      IL-6, MCP-1 and MMP-1 all decreased in different degrees. CONCLUSIONS: It 
      indicated that DOE could inhibit the secretion of SASP factors and was a 
      promising natural antiaging agent.
CI  - (c) 2023 Shanghai Jahwa United Co., Ltd. Journal of Cosmetic Dermatology published 
      by Wiley Periodicals LLC.
FAU - Li, Lingyu
AU  - Li L
AD  - Shanghai Jahwa United Co., Ltd., Shanghai, China.
FAU - Zhu, Le
AU  - Zhu L
AD  - Shanghai Jahwa United Co., Ltd., Shanghai, China.
FAU - Chen, Mo
AU  - Chen M
AD  - Shanghai Jahwa United Co., Ltd., Shanghai, China.
FAU - Zhao, Ya
AU  - Zhao Y
AD  - Shanghai Jahwa United Co., Ltd., Shanghai, China.
FAU - Jia, Haidong
AU  - Jia H
AD  - Shanghai Jahwa United Co., Ltd., Shanghai, China.
LA  - eng
PT  - Journal Article
DEP - 20231206
PL  - England
TA  - J Cosmet Dermatol
JT  - Journal of cosmetic dermatology
JID - 101130964
RN  - 0 (Interleukin-6)
RN  - EC 3.4.24.7 (Matrix Metalloproteinase 1)
RN  - BBX060AN9V (Hydrogen Peroxide)
SB  - IM
MH  - Humans
MH  - *Interleukin-6
MH  - Senescence-Associated Secretory Phenotype
MH  - Cellular Senescence
MH  - *Dendrobium
MH  - Matrix Metalloproteinase 1
MH  - Hydrogen Peroxide/pharmacology
MH  - Fibroblasts
OTO - NOTNLM
OT  - Dendrobium officinale extract
OT  - SASP
OT  - antiaging
OT  - human skin fibroblasts
EDAT- 2023/12/06 12:42
MHDA- 2024/03/29 06:46
CRDT- 2023/12/06 08:18
PHST- 2023/10/24 00:00 [revised]
PHST- 2023/08/09 00:00 [received]
PHST- 2023/11/13 00:00 [accepted]
PHST- 2024/03/29 06:46 [medline]
PHST- 2023/12/06 12:42 [pubmed]
PHST- 2023/12/06 08:18 [entrez]
AID - 10.1111/jocd.16101 [doi]
PST - ppublish
SO  - J Cosmet Dermatol. 2024 Apr;23(4):1360-1364. doi: 10.1111/jocd.16101. Epub 2023 
      Dec 6.