PMID- 38061145
OWN - NLM
STAT- MEDLINE
DCOM- 20240105
LR  - 20240116
IS  - 1879-3363 (Electronic)
IS  - 0025-326X (Linking)
VI  - 198
DP  - 2024 Jan
TI  - Plastic pollution as a novel reservoir for the environmental survival of the drug 
      resistant fungal pathogen Candida auris.
PG  - 115841
LID - S0025-326X(23)01276-6 [pii]
LID - 10.1016/j.marpolbul.2023.115841 [doi]
AB  - The WHO recently classified Candida auris as a fungal pathogen of "critical 
      concern". Evidence suggests that C. auris emerged from the natural environment, 
      yet the ability of this pathogenic yeast to survive in the natural environment is 
      still poorly understood. The aim of this study, therefore, was to quantify the 
      persistence of C. auris in simulated environmental matrices and explore the role 
      of plastic pollution for facilitating survival and potential transfer of C. 
      auris. Multi-drug resistant strains of C. auris persisted for over 30 days in 
      river water or seawater, either planktonically, or in biofilms colonising 
      high-density polyethylene (HDPE) or glass. C. auris could be transferred from 
      plastic beads onto simulated beach sand, particularly when the sand was wet. 
      Importantly, all C. auris cells recovered from plastics retained their 
      pathogenicity; therefore, plastic pollution could play a significant role in the 
      widescale environmental dissemination of this recently emerged pathogen.
CI  - Copyright (c) 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Akinbobola, Ayorinde
AU  - Akinbobola A
AD  - Biological and Environmental Sciences, Faculty of Natural Sciences, University of 
      Stirling, Stirling, FK9 4LA, UK. Electronic address: 
      ayorinde.akinbobola@stir.ac.uk.
FAU - Kean, Ryan
AU  - Kean R
AD  - Department of Biological and Biomedical Sciences, School of Health and Life 
      Sciences, Glasgow Caledonian University, Glasgow, UK.
FAU - Quilliam, Richard S
AU  - Quilliam RS
AD  - Biological and Environmental Sciences, Faculty of Natural Sciences, University of 
      Stirling, Stirling, FK9 4LA, UK.
LA  - eng
PT  - Journal Article
DEP - 20231206
PL  - England
TA  - Mar Pollut Bull
JT  - Marine pollution bulletin
JID - 0260231
RN  - 0 (Sand)
SB  - IM
MH  - *Candida
MH  - *Candida auris
MH  - Sand
MH  - Fungi
MH  - Biofilms
MH  - Microbial Sensitivity Tests
OTO - NOTNLM
OT  - Anti-fungal drug resistance
OT  - Bathing water quality
OT  - Beach sand
OT  - Environmental pathogens
OT  - Human exposure
OT  - Plastisphere
COIS- Declaration of competing interest The authors declare the following financial 
      interests/personal relationships which may be considered as potential competing 
      interests: None.
EDAT- 2023/12/08 00:42
MHDA- 2024/01/05 06:42
CRDT- 2023/12/07 18:02
PHST- 2023/09/02 00:00 [received]
PHST- 2023/11/10 00:00 [revised]
PHST- 2023/11/21 00:00 [accepted]
PHST- 2024/01/05 06:42 [medline]
PHST- 2023/12/08 00:42 [pubmed]
PHST- 2023/12/07 18:02 [entrez]
AID - S0025-326X(23)01276-6 [pii]
AID - 10.1016/j.marpolbul.2023.115841 [doi]
PST - ppublish
SO  - Mar Pollut Bull. 2024 Jan;198:115841. doi: 10.1016/j.marpolbul.2023.115841. Epub 
      2023 Dec 6.