PMID- 38073901
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231211
IS  - 2220-3206 (Print)
IS  - 2220-3206 (Electronic)
IS  - 2220-3206 (Linking)
VI  - 13
IP  - 11
DP  - 2023 Nov 19
TI  - Effects of combined spinal-epidural anesthesia on anxiety, labor analgesia and 
      motor blocks in women during natural delivery.
PG  - 838-847
LID - 10.5498/wjp.v13.i11.838 [doi]
AB  - BACKGROUND: The background of this study was analgesia in natural delivery. The 
      combined spinal-epidural anesthesia has obvious analgesic effect on the 
      parturients in natural labor, and combined spinal-epidural anesthesia has been 
      widely used in anesthesia for various diseases. AIM: To study the effects of 
      combined spinal-epidural anesthesia on anxiety, labor analgesia, and motor blocks 
      in parturients during natural delivery. METHODS: A total of 120 women who gave 
      birth at Changning District Maternal and Child Health Hospital between December 
      2021 to December 2022 were included; a random number table approach was employed 
      to divide the women into a control group and a joint group, with each group 
      consisting of 60 women. The control group was given epidural anesthesia, while 
      the joint group was given combined spinal-epidural anesthesia. The visual analog 
      scale (VAS) was used to evaluate the degree of maternal pain. Comparisons were 
      made between the two groups' conditions of childbirth and the duration of labor. 
      Apgar scores were used to evaluate the status of the newborns at birth; 
      Self-rating Anxiety Scale (SAS) and General Self-Efficacy Scale (GSES) scores, 
      umbilical artery blood gas analysis indices and stress indices were compared 
      between the two groups; and the frequencies of motor block and postpartum 
      complications were analyzed. RESULTS: In comparison to the control group, in the 
      joint group, the VAS scores for the first, second, and third stages of labor were 
      lower (P < 0.05). The rates of conversion to cesarean section and postpartum 
      blood loss in the joint group were lower than those in the control group (P < 
      0.05). No significant differences were observed in the Apgar score, the duration 
      of the first stage of labor, or the total duration of labor between the two 
      groups (P > 0.05). The second and third stages of labor in the joint group were 
      shorter than those in the control group (P < 0.05). When compared to the control 
      group, the postpartum SAS score of the joint group was lower, while the GSES 
      score was greater (P < 0.05). Between the control group and the joint group, the 
      differences observed in pH, arterial carbon dioxide partial pressure, arterial 
      oxygen partial pressure, or arterial hydrogen ion concentration were not 
      significant (P > 0.05). Nitric oxide, cortisol, and adrenaline levels were lower 
      in the joint group than in the control group (P < 0.05). There were no 
      substantial differences in Bromage grade or rate of complications between the two 
      groups (P > 0.05). CONCLUSION: For parturients during natural delivery, combined 
      spinal-epidural anesthesia can reduce anxiety, provide labor analgesia, shorten 
      labor time, and reduce postoperative stress levels but did not result in a motor 
      block.
CI  - (c)The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Cai, Ling
AU  - Cai L
AD  - Department of Anesthesiology, Shanghai Changning Maternity & Infant Health 
      Hospital, Shanghai 200050, China.
FAU - Jiang, Jiao-Jiao
AU  - Jiang JJ
AD  - Department of Anesthesiology, Shanghai Changning Maternity & Infant Health 
      Hospital, Shanghai 200050, China.
FAU - Wang, Ting-Ting
AU  - Wang TT
AD  - Department of Anesthesiology, Shanghai Changning Maternity & Infant Health 
      Hospital, Shanghai 200050, China.
FAU - Cao, Shuang
AU  - Cao S
AD  - Department of Anesthesiology, Shanghai Changning Maternity & Infant Health 
      Hospital, Shanghai 200050, China. 13817340402@163.com.
LA  - eng
PT  - Journal Article
DEP - 20231119
PL  - United States
TA  - World J Psychiatry
JT  - World journal of psychiatry
JID - 101610480
PMC - PMC10701213
OTO - NOTNLM
OT  - Anxiety level
OT  - Combined spinal-epidural anesthesia
OT  - Labor analgesia
OT  - Motor block
OT  - Natural delivery
COIS- Conflict-of-interest statement: All the authors report no relevant conflicts of 
      interest for this article.
EDAT- 2023/12/11 06:45
MHDA- 2023/12/11 06:46
PMCR- 2023/11/19
CRDT- 2023/12/11 05:37
PHST- 2023/07/18 00:00 [received]
PHST- 2023/08/28 00:00 [revised]
PHST- 2023/09/22 00:00 [accepted]
PHST- 2023/12/11 06:46 [medline]
PHST- 2023/12/11 06:45 [pubmed]
PHST- 2023/12/11 05:37 [entrez]
PHST- 2023/11/19 00:00 [pmc-release]
AID - 10.5498/wjp.v13.i11.838 [doi]
PST - epublish
SO  - World J Psychiatry. 2023 Nov 19;13(11):838-847. doi: 10.5498/wjp.v13.i11.838. 
      eCollection 2023 Nov 19.