PMID- 38078683
OWN - NLM
STAT- Publisher
LR  - 20231211
IS  - 1520-6777 (Electronic)
IS  - 0733-2467 (Linking)
DP  - 2023 Dec 11
TI  - Outcomes of women diagnosed with primary bladder neck obstruction based on video 
      urodynamic criteria.
LID - 10.1002/nau.25349 [doi]
AB  - OBJECTIVE: Functional and anatomic bladder outlet obstruction (BOO) in women are 
      more prevalent than previously suspected and remain a diagnostic challenge. 
      Several urodynamic diagnostic criteria for female BOO have been proposed, but 
      studies validating the criteria by assessing treatment outcomes are lacking. We 
      sought to correlate video urodynamic (VUD) diagnostic criteria with symptom 
      improvement in women with functional bladder outlet obstruction. METHODS: A 
      retrospective cohort study of women diagnosed with primary bladder neck 
      obstruction (PBNO) by VUD criteria who underwent bladder neck incision (BNI) 
      between 2010 and 2022 was performed. Patient demographic, clinical, and 
      urodynamic characteristics were collected before and after treatment and 
      analyzed. RESULTS: Twenty-six women with mean age 64.7 years underwent BNI. 
      Nineteen patients (73.1%) were cured, four (15.4%) improved, and three (11.5%) 
      failed. After BNI the mean postoperative Qmax was significantly higher (9.4 vs. 
      3 mL/s, p = 0.006) and mean postvoid residual (PVR) was significantly lower (102 
      vs. 514 mL, p </= 0.001). Patients who did not require a catheter preoperatively 
      were more likely to be cured than those who did (90% vs. 62.5%, p = 0.03). The 
      PdetQmax of patients that were cured or improved did not differ significantly 
      from those who were not (50.7 cm H(2) O vs. 32 cm H(2) O, p = 0.21). CONCLUSIONS: 
      The diagnosis of PBNO by VUD criteria for obstruction correlated with treatment 
      outcomes with success in 88.5% and 56% becoming catheter independent. Successful 
      treatment was independent of preoperative PdetQmax.
CI  - (c) 2023 Wiley Periodicals LLC.
FAU - Drain, Alice
AU  - Drain A
AUID- ORCID: 0000-0002-4571-5160
AD  - Departments of Urology and Obstetrics and Gynecology, Division of Female Pelvic 
      Medicine and Reconstructive Surgery, UCLA Health, Los Angeles, California, USA.
FAU - Volkin, Dmitry
AU  - Volkin D
AD  - Departments of Urology and Obstetrics and Gynecology, Division of Female Pelvic 
      Medicine and Reconstructive Surgery, UCLA Health, Los Angeles, California, USA.
FAU - Rosenblum, Nirit
AU  - Rosenblum N
AD  - Department of Urology, NYU Langone Medical Center, New York, New York, USA.
FAU - Brucker, Benjamin M
AU  - Brucker BM
AD  - Department of Urology, NYU Langone Medical Center, New York, New York, USA.
FAU - Nitti, Victor W
AU  - Nitti VW
AD  - Departments of Urology and Obstetrics and Gynecology, Division of Female Pelvic 
      Medicine and Reconstructive Surgery, UCLA Health, Los Angeles, California, USA.
LA  - eng
PT  - Journal Article
DEP - 20231211
PL  - United States
TA  - Neurourol Urodyn
JT  - Neurourology and urodynamics
JID - 8303326
SB  - IM
OTO - NOTNLM
OT  - bladder neck incision
OT  - primary bladder neck obstruction
OT  - video urodynamics
OT  - voiding dysfunction
OT  - women
EDAT- 2023/12/11 12:42
MHDA- 2023/12/11 12:42
CRDT- 2023/12/11 08:44
PHST- 2023/11/02 00:00 [revised]
PHST- 2023/07/05 00:00 [received]
PHST- 2023/11/25 00:00 [accepted]
PHST- 2023/12/11 12:42 [medline]
PHST- 2023/12/11 12:42 [pubmed]
PHST- 2023/12/11 08:44 [entrez]
AID - 10.1002/nau.25349 [doi]
PST - aheadofprint
SO  - Neurourol Urodyn. 2023 Dec 11. doi: 10.1002/nau.25349.