PMID- 38089626
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20240301
IS  - 1664-2392 (Print)
IS  - 1664-2392 (Electronic)
IS  - 1664-2392 (Linking)
VI  - 14
DP  - 2023
TI  - Robotic posterior retroperitoneal adrenalectomy versus laparoscopic posterior 
      retroperitoneal adrenalectomy: outcomes from a pooled analysis.
PG  - 1278007
LID - 10.3389/fendo.2023.1278007 [doi]
LID - 1278007
AB  - BACKGROUND: The comparative advantages of robotic posterior retroperitoneal 
      adrenalectomy (RPRA) over laparoscopic posterior retroperitoneal adrenalectomy 
      (LPRA) remain a topic of ongoing debate within the medical community. This 
      systematic literature review and meta-analysis aim to assess the safety and 
      efficacy of RPRA compared to LPRA, with the ultimate goal of determining which 
      procedure yields superior clinical outcomes. METHODS: A systematic search was 
      conducted on databases including PubMed, Embase, Web of Science, and the Cochrane 
      Library database to identify relevant studies, encompassing both randomized 
      controlled trials (RCTs) and non-RCTs, that compare the outcomes of RPRA and 
      LPRA. The primary focus of this study was to evaluate perioperative surgical 
      outcomes and complications. Review Manager 5.4 was used for this analysis. The 
      study was registered with PROSPERO (ID: CRD42023453816). RESULTS: A total of 
      seven non-RCTs were identified and included in this study, encompassing a cohort 
      of 675 patients. The findings indicate that RPRA exhibited superior performance 
      compared to LPRA in terms of hospital stay (weighted mean difference [WMD] -0.78 
      days, 95% confidence interval [CI] -1.46 to -0.10; p = 0.02). However, there were 
      no statistically significant differences observed between the two techniques in 
      terms of operative time, blood loss, transfusion rates, conversion rates, major 
      complications, and overall complications. CONCLUSION: RPRA is associated with a 
      significantly shorter hospital stay compared to LPRA, while demonstrating 
      comparable operative time, blood loss, conversion rate, and complication rate. 
      However, it is important to note that further research of a more comprehensive 
      and rigorous nature is necessary to validate these findings. SYSTEMATIC REVIEW 
      REGISTRATION: 
      https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=453816, 
      identifier CRD42023453816.
CI  - Copyright (c) 2023 Li, Chen, Wang, Yu, Deng and Liao.
FAU - Li, Yu-Gen
AU  - Li YG
AD  - Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nan 
      chong, China.
FAU - Chen, Xiao-Bin
AU  - Chen XB
AD  - Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nan 
      chong, China.
FAU - Wang, Chun-Mei
AU  - Wang CM
AD  - Physical Examination Center, Affiliated Hospital of North Sichuan Medical 
      College, Nan chong, China.
FAU - Yu, Xiao-Dong
AU  - Yu XD
AD  - Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nan 
      chong, China.
FAU - Deng, Xian-Zhong
AU  - Deng XZ
AD  - Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nan 
      chong, China.
FAU - Liao, Bo
AU  - Liao B
AD  - Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nan 
      chong, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20231128
PL  - Switzerland
TA  - Front Endocrinol (Lausanne)
JT  - Frontiers in endocrinology
JID - 101555782
SB  - IM
MH  - Humans
MH  - *Robotic Surgical Procedures/adverse effects/methods
MH  - *Laparoscopy/adverse effects/methods
MH  - Adrenalectomy/adverse effects/methods
MH  - Retroperitoneal Space/surgery
MH  - Blood Loss, Surgical
PMC - PMC10715275
OTO - NOTNLM
OT  - adrenalectomy
OT  - laparoscopic
OT  - meta-analysis
OT  - posterior
OT  - robotic
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/12/13 18:42
MHDA- 2023/12/17 09:46
PMCR- 2023/01/01
CRDT- 2023/12/13 12:54
PHST- 2023/08/15 00:00 [received]
PHST- 2023/11/06 00:00 [accepted]
PHST- 2023/12/17 09:46 [medline]
PHST- 2023/12/13 18:42 [pubmed]
PHST- 2023/12/13 12:54 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fendo.2023.1278007 [doi]
PST - epublish
SO  - Front Endocrinol (Lausanne). 2023 Nov 28;14:1278007. doi: 
      10.3389/fendo.2023.1278007. eCollection 2023.