PMID- 38089826
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1657-9534 (Electronic)
IS  - 0120-8322 (Print)
IS  - 0120-8322 (Linking)
VI  - 54
IP  - 3
DP  - 2023 Jul-Sep
TI  - Clinimetric properties of the Perme Intensive Care Unit Mobility Score -a 
      multicenter study for minimum important difference and responsiveness analysis.
PG  - e2005580
LID - 10.25100/cm.v54i3.5580 [doi]
LID - e2005580
AB  - BACKGROUND: The use of instruments in clinical practice with measurement 
      properties tested is highly recommended, in order to provide adequate assessment 
      and measurement of outcomes. OBJECTIVE: To calculate the minimum clinically 
      important difference (MCID) and responsiveness of the Perme Intensive Care Unit 
      Mobility Score (Perme Score). METHODS: This retrospective, multicentric study 
      investigated the clinimetric properties of MCID, estimated by constructing the 
      Receiver Operating Characteristic (ROC). Maximizing sensitivity and specificity 
      by Youden's, the ROC curve calibration was performed by the Hosmer and Lemeshow 
      goodness-of-fit test. Additionally, we established the responsiveness, floor and 
      ceiling effects, internal consistency, and predictive validity of the Perme 
      Score. RESULTS: A total of 1.200 adult patients records from four mixed general 
      intensive care units (ICUs) were included. To analyze which difference clinically 
      reflects a relevant evolution we calculated the area under the curve (AUC) of 
      0.96 (95% CI: 0.95-0.98), and the optimal cut-off value of 7.0 points was 
      established. No substantial floor (8.8%) or ceiling effects (4.9%) were observed 
      at ICU discharge. However, a moderate floor effect was observed at ICU admission 
      (19.3%), in contrast to a very low incidence of ceiling effect (0.6%). The Perme 
      Score at ICU admission was associated with hospital mortality, OR 0.86 (95% CI: 
      0.82-0.91), and the predictive validity for ICU stay presented a mean ratio of 
      0.97 (95% CI: 0.96-0.98). CONCLUSION: Our findings support the establishment of 
      the minimum clinically important difference and responsiveness of the Perme Score 
      as a measure of mobility status in the ICU.
CI  - Copyright (c) 2023 Colombia Medica.
FAU - Kenji Nawa, Ricardo
AU  - Kenji Nawa R
AUID- ORCID: 0000-0002-0852-7013
AD  - Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
FAU - Luiz Ferreira De Camillis, Marcio
AU  - Luiz Ferreira De Camillis M
AUID- ORCID: 0000-0001-5566-6422
AD  - Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.
FAU - Buttignol, Monique
AU  - Buttignol M
AUID- ORCID: 0000-0002-7195-6400
AD  - Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
AD  - Hospital Municipal da Vila Santa Catarina Dr. Gilson de Cassia Marques de 
      Carvalho;Sao Paulo, SP, Brazil.
FAU - Machado Kutchak, Fernanda
AU  - Machado Kutchak F
AUID- ORCID: 0000-0002-5717-0380
AD  - Universidade Vale dos Sinos, Porto Alegre, RS, Brazil.
AD  - Universidade Federal do Rio Grande do Sul, Postgraduate Program in Health 
      Sciences: Cardiology and Cardiovascular Sciences, Porto Alegre, RS, Brazil.
FAU - Chaves Pacheco, Eder
AU  - Chaves Pacheco E
AUID- ORCID: 0000-0001-7367-854X
AD  - Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
FAU - Rodrigues Goncalves, Louise Helena
AU  - Rodrigues Goncalves LH
AUID- ORCID: 0000-0002-2386-9847
AD  - Hospital Municipal da Vila Santa Catarina Dr. Gilson de Cassia Marques de 
      Carvalho;Sao Paulo, SP, Brazil.
FAU - Correa Garcia, Leonardo Miguel
AU  - Correa Garcia LM
AUID- ORCID: 0000-0002-5730-3147
AD  - Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.
FAU - Tavares Timenetsky, Karina
AU  - Tavares Timenetsky K
AUID- ORCID: 0000-0002-4176-2445
AD  - Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
FAU - Forgiarini, Luiz Alberto
AU  - Forgiarini LA
AUID- ORCID: 0000-0002-6706-2703
AD  - Universidade Catolica de Pelotas - UCPel, Medicine Course, Postgraduate Program 
      in Health and Behavior, Pelotas, RS, Brazil.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20230925
PL  - Colombia
TA  - Colomb Med (Cali)
JT  - Colombia medica (Cali, Colombia)
JID - 9212578
SB  - IM
MH  - Adult
MH  - Humans
MH  - Retrospective Studies
MH  - *Intensive Care Units
MH  - ROC Curve
PMC - PMC10714681
OTO - NOTNLM
OT  - Calibration
OT  - Health Care
OT  - Intensive care unit
OT  - Outcome Assessment
OT  - ROC Curve
OT  - clinimetric properties
OT  - outcome measures
OT  - rehabilitation
COIS- Conflicts of Interest: The authors declare no conflicts of interest.
EDAT- 2023/12/13 18:42
MHDA- 2023/12/17 13:19
PMCR- 2023/09/25
CRDT- 2023/12/13 12:58
PHST- 2023/04/04 00:00 [received]
PHST- 2023/06/09 00:00 [revised]
PHST- 2023/09/21 00:00 [accepted]
PHST- 2023/12/17 13:19 [medline]
PHST- 2023/12/13 18:42 [pubmed]
PHST- 2023/12/13 12:58 [entrez]
PHST- 2023/09/25 00:00 [pmc-release]
AID - 10.25100/cm.v54i3.5580 [doi]
PST - epublish
SO  - Colomb Med (Cali). 2023 Sep 25;54(3):e2005580. doi: 10.25100/cm.v54i3.5580. 
      eCollection 2023 Jul-Sep.