PMID- 38091596
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20240319
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 53
IP  - 4
DP  - 2023 Dec 20
TI  - Hyperbaric oxygen treatment in delayed post-hypoxic encephalopathy following 
      inhalation of liquefied petroleum gas: a case report.
PG  - 351-355
LID - 10.28920/dhm53.4.351-355 [doi]
AB  - Delayed post-hypoxic encephalopathy can occur after an episode of anoxia or 
      hypoxia. Symptoms include apathy, confusion, and neurological deficits. We 
      describe a 47-year-old male patient who inhaled gas from a kitchen stove liquid 
      petroleum gas cylinder. He was diagnosed with hypoxic ischaemic encephalopathy 12 
      hours after his emergency department admission. He received six sessions of 
      hyperbaric oxygen treatment (HBOT) and was discharged in a healthy state after 
      six days. Fifteen days later, he experienced weakness, loss of appetite, 
      forgetfulness, depression, balance problems, and inability to perform self-care. 
      One week later, he developed urinary and fecal incontinence and was diagnosed 
      with post-hypoxic encephalopathy. After 45 days from the onset of symptoms, he 
      was referred to the Underwater and Hyperbaric Medicine Department for HBOT. The 
      patient exhibited poor self-care and slow speech rate, as well as ataxic gait and 
      dysdiadochokinesia. Hyperbaric oxygen was administered for twenty-four sessions, 
      which significantly improved the patient's neurological status with only 
      hypoesthesia in the left hand remaining at the end of treatment. Hyperbaric 
      oxygen has been reported as successful in treating some cases of delayed 
      neurological sequelae following CO intoxication. It is possible that HBO therapy 
      may also be effective in delayed post-hypoxic encephalopathy from other causes. 
      This may be achieved through mechanisms such as transfer of functional 
      mitochondria to the injury site, remyelination of damaged neurons, angiogenesis 
      and neurogenesis, production of anti-inflammatory cytokines, and balancing of 
      inflammatory and anti-inflammatory cytokines.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Canarslan Demir, Kubra
AU  - Canarslan Demir K
AD  - Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane 
      Training and Research Hospital, Ankara, Turkey.
AD  - Dr Kubra Canarslan Demir, SBU-Gulhane Egitim ve Arastirma Hastanesi, Sualti 
      Hekimligi ve Hiperbarik Tip Klinigi, Etlik/Ankara, Turkey, ORCiD: 
      0000-0001-6911-2375, drcanarslan@hotmail.com.
FAU - Turgut, Burak
AU  - Turgut B
AD  - Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane 
      Training and Research Hospital, Ankara, Turkey.
FAU - Ozgok Kangal, Kubra
AU  - Ozgok Kangal K
AD  - Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane 
      Training and Research Hospital, Ankara, Turkey.
FAU - Zaman, Taylan
AU  - Zaman T
AD  - Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane 
      Training and Research Hospital, Ankara, Turkey.
FAU - Simsek, Kemal
AU  - Simsek K
AD  - Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane 
      Training and Research Hospital, Ankara, Turkey.
LA  - eng
PT  - Case Reports
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Petroleum)
RN  - 0 (Cytokines)
SB  - IM
MH  - Male
MH  - Humans
MH  - Middle Aged
MH  - *Hyperbaric Oxygenation
MH  - Oxygen
MH  - *Hypoxia, Brain/etiology/therapy
MH  - Hypoxia/etiology/therapy
MH  - Anti-Inflammatory Agents
MH  - *Petroleum
MH  - Cytokines
PMC - PMC10944663
OTO - NOTNLM
OT  - Brain
OT  - Dementia
OT  - Hyperbaric medicine
OT  - Neurology
OT  - Toxicity
COIS- Conflict of interest and funding: nil
EDAT- 2023/12/13 18:42
MHDA- 2023/12/17 09:43
PMCR- 2024/12/20
CRDT- 2023/12/13 16:53
PHST- 2023/07/27 00:00 [received]
PHST- 2023/09/03 00:00 [accepted]
PHST- 2024/12/20 00:00 [pmc-release]
PHST- 2023/12/17 09:43 [medline]
PHST- 2023/12/13 18:42 [pubmed]
PHST- 2023/12/13 16:53 [entrez]
AID - 10.28920/dhm53.4.351-355 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2023 Dec 20;53(4):351-355. doi: 10.28920/dhm53.4.351-355.