PMID- 38100729
OWN - NLM
STAT- MEDLINE
DCOM- 20240404
LR  - 20240404
IS  - 1442-2050 (Electronic)
IS  - 1120-8694 (Linking)
VI  - 37
IP  - 4
DP  - 2024 Apr 2
TI  - Effectiveness and safety of stag beetle knife (SB knife) in management of 
      Zenker's diverticulum: a systematic review and meta-analysis.
LID - doad069 [pii]
LID - 10.1093/dote/doad069 [doi]
AB  - Stag Beetle Knife (SB Knife) is increasingly being utilized for Zenker's 
      Diverticulectomy (ZD). Our study assessed the effectiveness and safety of the SB 
      Knife for the management of ZD. Ovid EBM reviews, Ovid Embase, Ovid Medline, 
      ClinicalTrials.gov, Scopus, and Web of Science were searched to identify studies 
      that utilized SB knife for ZD. Pooled proportions (PP) were calculated using the 
      random-effects model. Heterogeneity was evaluated using I2 statistics. A total of 
      7 studies with 268 patients were included in the final analysis. Dysphagia and 
      regurgitation were the most common clinical symptoms. The mean size of the ZD was 
      2.8 +/- 0.7 cm and 28 (of 148) patients had undergone previous treatments. The PP 
      of technical success was 98% (95% CI: 92.3-99.5; I20) with a mean procedure 
      duration of 26.2 +/- 8.3 minutes. The PP of clinical response at first follow-up 
      and relapse after index procedure was 87.9% (95% CI: 81.6-92.3; I219) and 13.5% 
      (95% CI: 9.6-18.6; I22), respectively. At final follow-up, the PP of clinical 
      remission was 96.2% (95% CI: 91-98.4; I230.6) while the PP of procedure failure 
      was 3.6% (95% CI: 1.6-8.1; I20). No severe adverse events (AEs) were noted while 
      using the SB Knife. However, the PP of intraprocedural and postprocedural AEs was 
      13.2% (95% CI: 9.6-17.8; I20) and 9.3% (95% CI: 5.7-14.9; I2 < 20.9), 
      respectively. SB Knife is highly safe and effective for Zenker's Diverticulectomy 
      with a failure rate of only 3.6%.
CI  - (c) The Author(s) 2023. Published by Oxford University Press on behalf of 
      International Society for Diseases of the Esophagus. All rights reserved. For 
      permissions, please e-mail: journals.permissions@oup.com.
FAU - Dahiya, Dushyant Singh
AU  - Dahiya DS
AD  - Division of Gastroenterology, Hepatology & Motility, The University of Kansas 
      School of Medicine, Kansas City, KS, USA.
FAU - Deliwala, Smit
AU  - Deliwala S
AD  - Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA, 
      USA.
FAU - Chandan, Saurabh
AU  - Chandan S
AD  - Division of Gastroenterology & Hepatology, CHI Creighton University Medical 
      Center, Omaha, NE, USA.
FAU - Ramai, Daryl
AU  - Ramai D
AD  - Department of Gastroenterology, University of Utah, Salt Lake City, UT, USA.
FAU - Ali, Hassam
AU  - Ali H
AD  - Division of Gastroenterology and Hepatology, East Carolina University/Brody 
      School of Medicine, Greenville, NC, USA.
FAU - Kassab, Lena L
AU  - Kassab LL
AD  - Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
FAU - Facciorusso, Antonio
AU  - Facciorusso A
AD  - Gastroenterology Unit, Department of Surgical and Medical Sciences, University of 
      Foggia, Foggia, Italy.
FAU - Kochhar, Gursimran S
AU  - Kochhar GS
AD  - Division of Gastroenterology, Hepatology & Nutrition, Allegheny Health Network, 
      Pittsburgh, PA, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - United States
TA  - Dis Esophagus
JT  - Diseases of the esophagus : official journal of the International Society for 
      Diseases of the Esophagus
JID - 8809160
SB  - IM
MH  - Humans
MH  - Esophagoscopy/methods
MH  - *Zenker Diverticulum/surgery
MH  - *Deglutition Disorders
MH  - Recurrence
MH  - Treatment Outcome
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Zenker's Diverticulectomy
OT  - Zenker's diverticulum
OT  - adverse events
OT  - clinical remission
OT  - stag beetle knife
EDAT- 2023/12/15 18:41
MHDA- 2024/04/04 06:45
CRDT- 2023/12/15 16:02
PHST- 2023/09/02 00:00 [received]
PHST- 2023/11/24 00:00 [accepted]
PHST- 2024/04/04 06:45 [medline]
PHST- 2023/12/15 18:41 [pubmed]
PHST- 2023/12/15 16:02 [entrez]
AID - 7473334 [pii]
AID - 10.1093/dote/doad069 [doi]
PST - ppublish
SO  - Dis Esophagus. 2024 Apr 2;37(4):doad069. doi: 10.1093/dote/doad069.