PMID- 38103320
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240113
IS  - 2210-2612 (Print)
IS  - 2210-2612 (Electronic)
IS  - 2210-2612 (Linking)
VI  - 114
DP  - 2024 Jan
TI  - Multifocal giant cell tumor of the carpus: Unusual presentation. Case report and 
      review of the literature.
PG  - 109127
LID - S2210-2612(23)01256-7 [pii]
LID - 10.1016/j.ijscr.2023.109127 [doi]
LID - 109127
AB  - INTRODUCTION AND IMPORTANCE: Giant cell tumors (GCTs) of bone in the carpus are 
      rare. Carpal GCTs are usually solitary lesions; multifocal involvement is 
      exceptional. These lesions have a higher risk of local recurrence after 
      intralesional curettage than those in other body areas. CASE PRESENTATION: We 
      present a case of a 28-year-old male with a six-month history of a palpable mass 
      in the dorsal aspect of the left wrist. Physical examination revealed a 2 cm, 
      mildly tender mass. Magnetic resonance revealed a large intermediate signal 
      lesion involving completely hamate bone and the distal portion of the triquetrum. 
      Histological examination confirmed a giant cell tumor of the carpus. The patient 
      underwent en-bloc resection of the hamate bone extending to the distal part of 
      the pyramidal. The defect was reconstructed using polymethylmethacrylate cement 
      (PMMA), and intercarpal arthrodesis with the capitate was achieved. Follow-up at 
      18 months revealed a good clinical evolution, wrist range of motion of 30 degrees  of 
      extension, 30 degrees  of flexion, and 10 degrees  of ulnar and radial deviation without evidence 
      of tumoral recurrence. CLINICAL DISCUSSION: The current literature suggests a 
      high incidence of local recurrence in carpal GCT, so wide excision with carpal 
      arthrodesis is recommended, especially in Campanacci III and multifocal 
      involvement. CONCLUSION: Carpal GCT is exceptional, mainly affecting the hamate, 
      capitate, and scaphoid. Most literature supports wide excision of carpal GCT 
      owing to the high recurrence rate with intralesional procedures.
CI  - Copyright (c) 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Mier, Luis Carlos Gomez
AU  - Mier LCG
AD  - Department of Orthopaedic Oncology, National Cancer Institute, Bogota 111511, 
      Colombia. Electronic address: lgomezm@cancer.gov.co.
FAU - Montoya, Camilo Soto
AU  - Montoya CS
AD  - Department of Orthopaedic Oncology, National Cancer Institute, Bogota 111511, 
      Colombia.
FAU - Betancur, Andrea Franco
AU  - Betancur AF
AD  - Department of Orthopaedic Oncology, National Cancer Institute, Bogota 111511, 
      Colombia.
FAU - Chaustre, Juan Fernando
AU  - Chaustre JF
AD  - Department of Orthopaedic Oncology, National Cancer Institute, Bogota 111511, 
      Colombia.
FAU - Ramirez, Andres Felipe
AU  - Ramirez AF
AD  - Department of Orthopaedic Oncology, Universidad Militar Nueva Granada, Bogota 
      11011, Colombia; Department of Orthopaedic Oncology, National Cancer Institute, 
      Bogota 11011, Colombia. Electronic address: 
      est.andres.ramirez6@unimilitar.edu.co.
FAU - Arroyave Rivera, Sergio A
AU  - Arroyave Rivera SA
AD  - Department of Orthopaedic Oncology, Universidad Militar Nueva Granada, Bogota 
      11011, Colombia; Department of Orthopaedic Oncology, National Cancer Institute, 
      Bogota 11011, Colombia. Electronic address: 
      est.sergio.arroyave@unimilitar.edu.co.
LA  - eng
PT  - Case Reports
DEP - 20231208
PL  - Netherlands
TA  - Int J Surg Case Rep
JT  - International journal of surgery case reports
JID - 101529872
PMC - PMC10770590
OTO - NOTNLM
OT  - Arthrodesis
OT  - Carpus
OT  - Case report
OT  - Giant cell tumor
OT  - Hamate
OT  - Triquetrum
COIS- Declaration of competing interest The authors have no conflict of interest to 
      declare.
EDAT- 2023/12/17 09:43
MHDA- 2023/12/17 09:44
PMCR- 2023/12/08
CRDT- 2023/12/16 18:02
PHST- 2023/11/07 00:00 [received]
PHST- 2023/11/30 00:00 [revised]
PHST- 2023/12/03 00:00 [accepted]
PHST- 2023/12/17 09:44 [medline]
PHST- 2023/12/17 09:43 [pubmed]
PHST- 2023/12/16 18:02 [entrez]
PHST- 2023/12/08 00:00 [pmc-release]
AID - S2210-2612(23)01256-7 [pii]
AID - 109127 [pii]
AID - 10.1016/j.ijscr.2023.109127 [doi]
PST - ppublish
SO  - Int J Surg Case Rep. 2024 Jan;114:109127. doi: 10.1016/j.ijscr.2023.109127. Epub 
      2023 Dec 8.