PMID- 38103671
OWN - NLM
STAT- MEDLINE
DCOM- 20240129
LR  - 20240206
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 257
IP  - Pt 2
DP  - 2024 Feb
TI  - Chitosan nanoparticles loaded with Eucommia ulmoides seed essential oil: 
      Preparation, characterization, antioxidant and antibacterial properties.
PG  - 128820
LID - S0141-8130(23)05719-7 [pii]
LID - 10.1016/j.ijbiomac.2023.128820 [doi]
AB  - Eucommia ulmoides seed essential oil (EUSO) is a natural plant oil rich in 
      various nutrients, which has been widely used due to its unique medicinal 
      effects. However, it is prone to oxidation and rancidity under many adverse 
      environmental influences. Nanoencapsulation technology can protect and slow down 
      the loss of its biological activity. In this study, chitosan nanoparticles 
      (CSNPs) loaded with EUSO were prepared by emulsification and ionic gel 
      technology. EUSO-CSNPs were characterized by Fourier transform infrared (FTIR) 
      spectroscopy, Thermogravimetric analysis (TGA) and X-ray diffraction (XRD). The 
      results confirmed the success of EUSO encapsulation and the encapsulation rate 
      ranged from 36.95 % to 67.80 %. Nanoparticle size analyzer, Scanning electron 
      microscope (SEM) and Transmission electron microscopy (TEM) showed that CSNPs 
      were spherical particles with a range of 200.6-276.0 nm. The results of in vitro 
      release study indicated that the release of EUSO was phased, and EUSO-CSNPS had 
      certain sustained-release properties. Furthermore, EUSO-CSNPs had higher 
      antioxidant and antibacterial abilities than pure EUSO and chitosan, which was 
      verified through free radical scavenging experiments and bacteria biofilm 
      experiments, respectively. This technology can enhance the medicinal value of 
      EUSO in biomedical and other fields, and will provide support for in vivo 
      research of EUSO-CSNPs in the future.
CI  - Copyright (c) 2023 Elsevier B.V. All rights reserved.
FAU - Jiang, Xin
AU  - Jiang X
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Yu, Yufan
AU  - Yu Y
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Ma, Shuting
AU  - Ma S
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Li, Lianshi
AU  - Li L
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Yu, Meiqi
AU  - Yu M
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Han, Meijie
AU  - Han M
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Yuan, Zuoqing
AU  - Yuan Z
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China.
FAU - Zhang, Jianyong
AU  - Zhang J
AD  - School of Life and Medicine, Shandong University of Technology, Zibo 255000, 
      Shandong, China. Electronic address: zhangjy2003@sdut.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20231214
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
RN  - 0 (Oils, Volatile)
RN  - 0 (Antioxidants)
RN  - 9012-76-4 (Chitosan)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - *Oils, Volatile/chemistry
MH  - Antioxidants/pharmacology/analysis
MH  - *Chitosan/chemistry
MH  - *Eucommiaceae/chemistry
MH  - Anti-Bacterial Agents/pharmacology/analysis
MH  - *Nanoparticles/chemistry
MH  - Seeds/chemistry
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Particle Size
OTO - NOTNLM
OT  - Antioxidant and antibacterial
OT  - Chitosan nanoparticals
OT  - Eucommia ulmoides seed essential oil
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/12/17 09:42
MHDA- 2024/01/29 06:44
CRDT- 2023/12/16 19:26
PHST- 2023/09/22 00:00 [received]
PHST- 2023/12/01 00:00 [revised]
PHST- 2023/12/13 00:00 [accepted]
PHST- 2024/01/29 06:44 [medline]
PHST- 2023/12/17 09:42 [pubmed]
PHST- 2023/12/16 19:26 [entrez]
AID - S0141-8130(23)05719-7 [pii]
AID - 10.1016/j.ijbiomac.2023.128820 [doi]
PST - ppublish
SO  - Int J Biol Macromol. 2024 Feb;257(Pt 2):128820. doi: 
      10.1016/j.ijbiomac.2023.128820. Epub 2023 Dec 14.