PMID- 38106795
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231219
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 11
DP  - 2023 Nov
TI  - Unusual Distribution of Cerebral Venous Thrombosis in a Patient With Sickle Cell 
      Disease: A Case Study.
PG  - e48828
LID - 10.7759/cureus.48828 [doi]
LID - e48828
AB  - This study presents the case of a 29-year-old Bahraini woman with a known history 
      of sickle cell disease who exhibited acute neurological symptoms. Advanced 
      imaging, specifically CT and MRI, identified cerebral venous thrombosis (CVT). 
      The patient was managed with fluid therapy and anticoagulation, and received a 
      packed red blood cell transfusion, leading to a complete recovery. Notably, this 
      case was marked by the patient's positive anti-double stranded DNA (anti-dsDNA) 
      status, typically linked with systemic lupus erythematosus (SLE), adding a 
      potential pro-coagulant factor. The occlusion pattern, particularly involving the 
      internal cerebral veins, was unique compared to other reviewed CVT cases in 
      patients with sickle cell disease. This case emphasizes the significance of early 
      diagnosis and intervention in CVT, especially in patients with sickle cell 
      disease and other predisposing factors.
CI  - Copyright (c) 2023, Alchalban et al.
FAU - Alchalban, Mohamed F
AU  - Alchalban MF
AD  - Radiology, Bahrain Defence Force Royal Medical Services, Military Hospital, 
      Riffa, BHR.
FAU - Alekri, Ahmed A
AU  - Alekri AA
AD  - Internal Medicine, Salmaniya Medical Complex, Manama, BHR.
FAU - Alkaabi, Shaikha M
AU  - Alkaabi SM
AD  - Internal Medicine, Bahrain Defence Force Royal Medical Services, Military 
      Hospital, Riffa, BHR.
FAU - Alhilly, Ali J
AU  - Alhilly AJ
AD  - Neurology, Bahrain Defence Force Royal Medical Services, Military Hospital, 
      Riffa, BHR.
FAU - Alomran, Bedoor S
AU  - Alomran BS
AD  - Radiology, Bahrain Defence Force Royal Medical Services, Military Hospital, 
      Riffa, BHR.
LA  - eng
PT  - Case Reports
DEP - 20231115
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10722348
OTO - NOTNLM
OT  - cerebral venous thrombosis (cvt)
OT  - internal cerebral vein thrombosis
OT  - sickle cell disease (scd)
OT  - sickle cell disease complications
OT  - vaso occlusive crisis
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/12/18 06:42
MHDA- 2023/12/18 06:43
PMCR- 2023/11/15
CRDT- 2023/12/18 04:45
PHST- 2023/11/14 00:00 [accepted]
PHST- 2023/12/18 06:43 [medline]
PHST- 2023/12/18 06:42 [pubmed]
PHST- 2023/12/18 04:45 [entrez]
PHST- 2023/11/15 00:00 [pmc-release]
AID - 10.7759/cureus.48828 [doi]
PST - epublish
SO  - Cureus. 2023 Nov 15;15(11):e48828. doi: 10.7759/cureus.48828. eCollection 2023 
      Nov.