PMID- 38114157 OWN - NLM STAT- MEDLINE DCOM- 20231221 LR - 20231221 IS - 1001-5302 (Print) IS - 1001-5302 (Linking) VI - 48 IP - 20 DP - 2023 Oct TI - [Evidence mapping analysis of traditional Chinese medicine intervention in pulmonary fibrosis]. PG - 5641-5650 LID - 10.19540/j.cnki.cjcmm.20230618.501 [doi] AB - This study utilized evidence mapping methodology to systematically identify, describe, and evaluate the evidence from relevant research on traditional Chinese medicine(TCM) interventions in patients with pulmonary fibrosis. CNKI, Wanfang, VIP, SinoMed, PubMed, Web of Science, EMbase, and Cochrane Library were searched from database inception to March 2023 for systematic reviews/Meta-analysis/network Meta-analysis on TCM interventions in pulmonary fibrosis. The quality of included studies was assessed using the AMSTAR 2 scale, and the evidence mapping approach was employed to present comprehensive information on populations, intervention methods, the sample size in systematic reviews/Meta-analysis, and conclusion classifications. Ultimately, 44 systematic reviews/Meta-analysis/network Meta-analysis were included. Apart from syndrome differentiation and treatment, TCM injections accounted for a significant proportion of the observed interventions. The treatment methods were mainly focused on nourishing Qi and Yin, promoting blood circulation, resolving stasis, and dredging collaterals. The results from the included studies demonstrated that TCM treatment for pulmonary fibrosis could improve efficacy, increase lung function, improve PaO_(2 )levels, increase the 6-minute walk distance(6MWD), alleviate clinical symptoms, and enhance patients' quality of life. Based on the assessment using the AMSTAR 2 scale, methodological issues were identified, including the lack of protocol registration, failure to provide a list of excluded literature, and incomplete explanations regarding the impact of heterogeneity and bias on the results. The evidence mapping revealed that 42 conclusions were beneficial, while two conclusions were potentially beneficial. Overall, the quality of evidence was relatively low, primarily due to methodological imprecision and publication bias. Although TCM showed certain efficacy in the treatment of pulmonary fibrosis, the quality of reported literature, methodological quality, and overall evidence quality need improvement. It is recommended to conduct high-quality and standardized studies in the future to provide better evidence-based guidance. FAU - Sun, Wen-Yu AU - Sun WY AD - Science and Information Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China. FAU - Zhang, Xue-Qin AU - Zhang XQ AD - Science and Information Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China. FAU - Guo, Yu-Jie AU - Guo YJ AD - Science and Information Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China. FAU - Deng, Hong-Yong AU - Deng HY AD - Science and Information Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China. LA - chi PT - English Abstract PT - Journal Article PT - Meta-Analysis PL - China TA - Zhongguo Zhong Yao Za Zhi JT - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JID - 8913656 SB - IM MH - Humans MH - *Medicine, Chinese Traditional MH - *Pulmonary Fibrosis/drug therapy MH - Quality of Life MH - Systematic Reviews as Topic MH - Network Meta-Analysis OTO - NOTNLM OT - AMSTAR 2 scale OT - evidence mapping OT - pulmonary fibrosis OT - traditional Chinese medicine EDAT- 2023/12/20 06:42 MHDA- 2023/12/21 06:43 CRDT- 2023/12/19 20:44 PHST- 2023/12/21 06:43 [medline] PHST- 2023/12/20 06:42 [pubmed] PHST- 2023/12/19 20:44 [entrez] AID - 10.19540/j.cnki.cjcmm.20230618.501 [doi] PST - ppublish SO - Zhongguo Zhong Yao Za Zhi. 2023 Oct;48(20):5641-5650. doi: 10.19540/j.cnki.cjcmm.20230618.501.