PMID- 38114412 OWN - NLM STAT- MEDLINE DCOM- 20240311 LR - 20240311 IS - 1878-1861 (Electronic) IS - 1878-1861 (Linking) VI - 27 IP - 3 DP - 2024 Mar TI - Cross-sectional associations between 24-hour movement behaviors and cardiometabolic health among adults with type 2 diabetes mellitus: A comparison according to weight status. PG - 179-186 LID - S1440-2440(23)00488-7 [pii] LID - 10.1016/j.jsams.2023.11.010 [doi] AB - OBJECTIVES: Type 2 diabetes mellitus (T2DM) is a chronic disease associated with overweight and obesity. Evidence suggests that 24-hour movement behaviors (24 h-MBs) play a crucial role in cardiometabolic health. However, it is not yet known if 24 h-MBs differ between weight status groups among people with T2DM (PwT2DM) and how 24 h-MBs are associated with their cardiometabolic health. DESIGN: Cross-sectional study. METHODS: Cardiometabolic variables (i.e. Body Mass Index (BMI), waist circumference (WC), HbA1c, fasting glucose, triglycerides, total-cholesterol, HDL-cholesterol, LDL-cholesterol, blood pressure) and 24 h-MBs (accelerometry and sleep-diary) of 1001 PwT2DM were collected. Regression models using compositional data analysis explored differences in 24 h-MBs between weight status groups and analyzed associations with cardiometabolic variables. RESULTS: The 24 h-MBs of PwT2DM being obese consisted of less sleep, light physical activity (LPA) and moderate to vigorous physical activity (MVPA) and more sedentary time (ST) per day as compared to PwT2DM being overweight or normal weight (p < 0.001). Regardless of weight status, the largest associations were found when reallocating 20 min a day from ST into MVPA for BMI (-0.32 kg/m(2); [-0.55; -0.09], -1.09 %), WC (-1.44 cm, [-2.26; -0.62], -1.35 %) and HDL-cholesterol (0.02 mmol/l, [0.01, 0.02], +1.59 %), as well as from ST into LPA for triglycerides (-0.04 mmol/l, [-0.05; -0.03], -2.3 %). Moreover, these associations were different when stratifying people by short-to-average (7.7 h/night) versus long sleep (9.3 h/night) period. CONCLUSIONS: This study highlights the importance of 24 h-MBs in the cardiometabolic health of PwT2DM. Shifting time from ST and/or sleep toward LPA or MVPA might theoretically benefit cardiometabolic health among relatively inactive PwT2DM, irrespective of weight status. CI - Copyright (c) 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. FAU - Willems, Iris AU - Willems I AD - Ghent University, Department of Rehabilitation Sciences, Belgium; Research Foundation Flanders, Belgium. Electronic address: Willems.iris@ugent.be. FAU - Verbestel, Vera AU - Verbestel V AD - Maastricht University, Department of Health Promotion, Research Institute of Nutrition and Translational Research in Metabolism & Care and Public Health Institute, the Netherlands. Electronic address: vera.verbestel@maastrichtuniversity.nl. FAU - Dumuid, Dorothea AU - Dumuid D AD - Alliance for Research in Exercise, Nutrition and Activity, Allied Health & Human Performance, University of South Australia, Australia. Electronic address: dot.dumuid@unisa.edu.au. FAU - Stanford, Tyman E AU - Stanford TE AD - Alliance for Research in Exercise, Nutrition and Activity, Allied Health & Human Performance, University of South Australia, Australia. Electronic address: ty.stanford@unisa.edu.au. FAU - Calders, Patrick AU - Calders P AD - Ghent University, Department of Rehabilitation Sciences, Belgium. Electronic address: Patrick.Calders@ugent.be. FAU - Lapauw, Bruno AU - Lapauw B AD - Department of Internal Medicine and Pediatrics & Department of Endocrinology, Ghent University Hospital & Ghent University, Belgium. Electronic address: Bruno.lapauw@uzgent.be. FAU - Bogaert, Lotte AU - Bogaert L AD - Ghent University, Department of Rehabilitation Sciences, Belgium. Electronic address: Lotte.Bogaert@ugent.be. FAU - Blom, Marieke T AU - Blom MT AD - Department of General Practice, Amsterdam UMC, location Vrije Universiteit, the Netherlands. Electronic address: m.t.blom@amsterdamumc.nl. FAU - den Braver, Nicolette R AU - den Braver NR AD - Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, the Netherlands. Electronic address: n.denbraver@amsterdamumc.nl. FAU - van der Velde, Jeroen H P M AU - van der Velde JHPM AD - Department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands. Electronic address: j.h.p.m.van_der_velde@lumc.nl. FAU - Rutters, Femke AU - Rutters F AD - Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, the Netherlands. Electronic address: f.rutters@amsterdamumc.nl. FAU - De Craemer, Marieke AU - De Craemer M AD - Ghent University, Department of Rehabilitation Sciences, Belgium. Electronic address: Marieke.DeCraemer@ugent.be. LA - eng PT - Journal Article DEP - 20231123 PL - Australia TA - J Sci Med Sport JT - Journal of science and medicine in sport JID - 9812598 RN - 0 (Triglycerides) RN - 0 (Cholesterol, HDL) SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2 MH - Cross-Sectional Studies MH - Risk Factors MH - Overweight MH - Obesity MH - Triglycerides MH - Cholesterol, HDL MH - Body Mass Index MH - *Cardiovascular Diseases MH - Waist Circumference/physiology OTO - NOTNLM OT - Cardiovascular diseases OT - Obesity OT - Overweight OT - Physical activity OT - Sedentary time OT - Sleep COIS- Declaration of interest statement The authors declare that they have no competing interests. EDAT- 2023/12/20 06:42 MHDA- 2024/03/11 06:43 CRDT- 2023/12/19 22:02 PHST- 2023/07/24 00:00 [received] PHST- 2023/10/25 00:00 [revised] PHST- 2023/11/17 00:00 [accepted] PHST- 2024/03/11 06:43 [medline] PHST- 2023/12/20 06:42 [pubmed] PHST- 2023/12/19 22:02 [entrez] AID - S1440-2440(23)00488-7 [pii] AID - 10.1016/j.jsams.2023.11.010 [doi] PST - ppublish SO - J Sci Med Sport. 2024 Mar;27(3):179-186. doi: 10.1016/j.jsams.2023.11.010. Epub 2023 Nov 23.