PMID- 38114704 OWN - NLM STAT- MEDLINE DCOM- 20240122 LR - 20240202 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 31 IP - 4 DP - 2024 Jan TI - Multi-residue monitoring and dietary risk assessment of 17 pesticides and 3 related metabolites in rice and rice flour from markets in China. PG - 5275-5288 LID - 10.1007/s11356-023-31618-x [doi] AB - Pesticide residues in rice have attracted widespread public attention in recent years. This research aimed to monitor the residues of 17 pesticides and their 3 metabolites in 120 samples of rice and rice flour collected from markets in China using the QuEChERS (Quick, Easy, Cheap, Effective, Rugged, Safe) pretreatment method combined with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The monitoring results showed that isoprothiolane, tricyclazole, fenoxanil, and tebuconazole were detected in the rice samples, with detection frequencies of 33.3%, 17.5%, 8.3%, and 2.5%, and concentrations ranging from 0.02 to 0.1 mg/kg (median = 0.04), 0.01 to 0.17 mg/kg (median = 0.14), 0.04 to 0.06 mg/kg (median = 0.05), and 0.01 to 0.02 mg/kg (median = 0.01), respectively. The residues of these four pesticides were all below their corresponding maximum residue levels (MRLs) set by China. Additionally, isoprothiolane, tricyclazole, fenoxanil, and tebuconazole were detected in rice flour samples, with detection frequencies of 74.2%, 55.0%, 5.0%, and 2.5%, and concentrations ranging from 0.01 to 0.1 mg/kg (median = 0.04), 0.01 to 0.04 mg/kg (median = 0.02), 0.01 to 0.06 mg/kg (median = 0.03), and 0.02 to 0.04 mg/kg (median = 0.03), respectively. Furthermore, the chronic dietary intake risk (HQ(c)), the acute dietary intake risk (HQ(a)), and cumulative dietary risk (HI) for all the detected pesticides were evaluated and found well below 100%, indicating that the dietary intake risks would not pose potential health risks. CI - (c) 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. FAU - Zhao, Jisheng AU - Zhao J AD - Lab of Pesticide Residues and Environmental Toxicology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China. FAU - Li, Pengfei AU - Li P AD - Lab of Pesticide Residues and Environmental Toxicology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China. FAU - Hu, Jiye AU - Hu J AUID- ORCID: 0000-0002-2520-7935 AD - Lab of Pesticide Residues and Environmental Toxicology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing, 100083, China. jyhu@ustb.edu.cn. LA - eng PT - Journal Article DEP - 20231219 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Pesticides) RN - 88HCS898G6 (isoprothiolane) RN - R7U3MEU7VR (tricyclazole) RN - 0 (Pesticide Residues) RN - 0 (Thiazoles) RN - 0 (Thiophenes) SB - IM MH - *Pesticides/analysis MH - Tandem Mass Spectrometry/methods MH - *Oryza/chemistry MH - Flour/analysis MH - *Pesticide Residues/analysis MH - Risk Assessment MH - Food Contamination/analysis MH - *Thiazoles MH - *Thiophenes OTO - NOTNLM OT - Dietary risk assessment OT - LC-MS/MS OT - Metabolites OT - Pesticide residues OT - Rice OT - Rice flour EDAT- 2023/12/20 06:42 MHDA- 2024/01/22 06:42 CRDT- 2023/12/19 23:49 PHST- 2023/09/15 00:00 [received] PHST- 2023/12/15 00:00 [accepted] PHST- 2024/01/22 06:42 [medline] PHST- 2023/12/20 06:42 [pubmed] PHST- 2023/12/19 23:49 [entrez] AID - 10.1007/s11356-023-31618-x [pii] AID - 10.1007/s11356-023-31618-x [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2024 Jan;31(4):5275-5288. doi: 10.1007/s11356-023-31618-x. Epub 2023 Dec 19.