PMID- 38115065
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231222
IS  - 2052-0492 (Print)
IS  - 2052-0492 (Electronic)
IS  - 2052-0492 (Linking)
VI  - 11
IP  - 1
DP  - 2023 Dec 19
TI  - Mechanical circulatory support in cardiogenic shock.
PG  - 64
LID - 10.1186/s40560-023-00710-2 [doi]
LID - 64
AB  - Cardiogenic shock is a complex and diverse pathological condition characterized 
      by reduced myocardial contractility. The goal of treatment of cardiogenic shock 
      is to improve abnormal hemodynamics and maintain adequate tissue perfusion in 
      organs. If hypotension and insufficient tissue perfusion persist despite initial 
      therapy, temporary mechanical circulatory support (t-MCS) should be initiated. 
      This decade sees the beginning of a new era of cardiogenic shock management using 
      t-MCS through the accumulated experience with use of intra-aortic balloon pump 
      (IABP) and venoarterial extracorporeal membrane oxygenation (VA-ECMO), as well as 
      new revolutionary devices or systems such as transvalvular axial flow pump 
      (Impella) and a combination of VA-ECMO and Impella (ECPELLA) based on the 
      knowledge of circulatory physiology. In this transitional period, we outline the 
      approach to the management of cardiogenic shock by t-MCS. The management strategy 
      involves carefully selecting one or a combination of the t-MCS devices, taking 
      into account the characteristics of each device and the specific pathological 
      condition. This selection is guided by monitoring of hemodynamics, classification 
      of shock stage, risk stratification, and coordinated management by the 
      multidisciplinary shock team.
CI  - (c) 2023. The Author(s).
FAU - Nakata, Jun
AU  - Nakata J
AUID- ORCID: 0000-0003-2476-1050
AD  - Division of Cardiovascular Intensive Care, Nippon Medical School Hospital, 1-1-5 
      Sendagi, Bunkyo-Ku, Tokyo, 113-8603, Japan. jun-nakata@nms.ac.jp.
FAU - Yamamoto, Takeshi
AU  - Yamamoto T
AD  - Division of Cardiovascular Intensive Care, Nippon Medical School Hospital, 1-1-5 
      Sendagi, Bunkyo-Ku, Tokyo, 113-8603, Japan.
FAU - Saku, Keita
AU  - Saku K
AD  - Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular 
      Center Research, Suita, Osaka, Japan.
FAU - Ikeda, Yuki
AU  - Ikeda Y
AD  - Department of Cardiovascular Medicine, Kitasato University, School of Medicine, 
      Sagamihara, Kanagawa, Japan.
FAU - Unoki, Takashi
AU  - Unoki T
AD  - Department of Cardiology and Intensive Care Unit, Saiseikai Kumamoto Hospital, 
      Kumamoto, Japan.
FAU - Asai, Kuniya
AU  - Asai K
AD  - Division of Cardiovascular Intensive Care, Nippon Medical School Hospital, 1-1-5 
      Sendagi, Bunkyo-Ku, Tokyo, 113-8603, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20231219
PL  - England
TA  - J Intensive Care
JT  - Journal of intensive care
JID - 101627304
PMC - PMC10731894
COIS- The authors declare that they have no competing interests.
EDAT- 2023/12/20 06:42
MHDA- 2023/12/20 06:43
PMCR- 2023/12/19
CRDT- 2023/12/20 00:20
PHST- 2023/10/11 00:00 [received]
PHST- 2023/11/30 00:00 [accepted]
PHST- 2023/12/20 06:43 [medline]
PHST- 2023/12/20 06:42 [pubmed]
PHST- 2023/12/20 00:20 [entrez]
PHST- 2023/12/19 00:00 [pmc-release]
AID - 10.1186/s40560-023-00710-2 [pii]
AID - 710 [pii]
AID - 10.1186/s40560-023-00710-2 [doi]
PST - epublish
SO  - J Intensive Care. 2023 Dec 19;11(1):64. doi: 10.1186/s40560-023-00710-2.