PMID- 38116571
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231221
IS  - 1726-6890 (Electronic)
IS  - 1735-0328 (Print)
IS  - 1726-6882 (Linking)
VI  - 22
IP  - 1
DP  - 2023 Jan-Dec
TI  - Bacillus coagulans T4 and Lactobacillus paracasei TD3 Ameliorate Skeletal Muscle 
      Oxidative Stress and Inflammation in High-Fat Diet-Fed C57BL/6J Mice.
PG  - e135249
LID - 10.5812/ijpr-135249 [doi]
LID - e135249
AB  - BACKGROUND: This study aims to investigate the effects of Bacillus coagulans T4 
      and Lactobacillus paracasei TD3 probiotics on skeletal muscle inflammation and 
      oxidative stress in C57BL/6J mice fed a high-fat diet (HFD). METHODS: Probiotics 
      B. coagulans T4, and L. paracasei TD3 were administered to male C57BL/6J mice fed 
      with HFD. The gene expression of macrophage infiltration markers, inflammatory 
      cytokines, and oxidative stress indicators in the muscle tissue was investigated. 
      RESULTS: Treatment with B. coagulans T4 and L. paracasei TD3 reduced macrophage 
      infiltration, accompanied by a decrease in the expression of monocyte 
      chemoattractant protein-1 (MCP-1) and an increase in the expression of 
      interleukin (IL)-10. On the other hand, L. paracasei TD3 decreased 
      malondialdehyde (MDA) while B. coagulans T4 decreased carbonyl and increased 
      catalase activity. CONCLUSIONS: Treatment with probiotics B. coagulans T4 and L. 
      paracasei TD3 partially ameliorated obesity-induced skeletal muscle inflammation 
      in HFD-fed mice.
CI  - Copyright (c) 2023, Shams et al.
FAU - Shams, Masoumeh
AU  - Shams M
AD  - Department of Medical Laboratory Sciences, School of Allied Medical Science, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Esmaeili, Fataneh
AU  - Esmaeili F
AD  - Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of 
      Medical Sciences Tehran, Iran.
FAU - Sadeghi, Samira
AU  - Sadeghi S
AD  - Department of Medical Laboratory Sciences, School of Allied Medical Science, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Shanaki-Bavarsad, Mahsa
AU  - Shanaki-Bavarsad M
AD  - Department of Neurology, Memory and Aging Center, University of California San 
      Francisco, San Francisco, CA, USA.
FAU - Seyyed Ebrahimi, Shadi Sadat
AU  - Seyyed Ebrahimi SS
AD  - Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of 
      Medical Sciences Tehran, Iran.
FAU - Hashemnia, Seyyed Mohammad Reza
AU  - Hashemnia SMR
AD  - Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of 
      Medical Sciences Tehran, Iran.
FAU - Tajabadi-Ebrahimi, Maryam
AU  - Tajabadi-Ebrahimi M
AUID- ORCID: 0000-0003-2780-3447
AD  - Department of Biology, Tehran Central Branch, Islamic Azad University, Tehran, 
      Iran.
FAU - Emamgholipour, Solaleh
AU  - Emamgholipour S
AD  - Department of Clinical Biochemistry, School of Medicine, Tehran University of 
      Medical Sciences, Tehran, Iran.
FAU - Shanaki, Mehrnoosh
AU  - Shanaki M
AD  - Department of Medical Laboratory Sciences, School of Allied Medical Science, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20230723
PL  - Netherlands
TA  - Iran J Pharm Res
JT  - Iranian journal of pharmaceutical research : IJPR
JID - 101208407
PMC - PMC10728858
OTO - NOTNLM
OT  - High-Fat Diet
OT  - Inflammation
OT  - Oxidative Stress
OT  - Probiotic
OT  - Skeletal Muscle
COIS- The authors declare that they have no competing interests.
EDAT- 2023/12/20 06:42
MHDA- 2023/12/20 06:43
PMCR- 2023/07/23
CRDT- 2023/12/20 04:05
PHST- 2023/01/28 00:00 [received]
PHST- 2023/06/03 00:00 [revised]
PHST- 2023/07/03 00:00 [accepted]
PHST- 2023/12/20 06:43 [medline]
PHST- 2023/12/20 06:42 [pubmed]
PHST- 2023/12/20 04:05 [entrez]
PHST- 2023/07/23 00:00 [pmc-release]
AID - 10.5812/ijpr-135249 [doi]
PST - epublish
SO  - Iran J Pharm Res. 2023 Jul 23;22(1):e135249. doi: 10.5812/ijpr-135249. 
      eCollection 2023 Jan-Dec.