PMID- 38122972 OWN - NLM STAT- MEDLINE DCOM- 20240219 LR - 20240219 IS - 1615-5947 (Electronic) IS - 0890-5096 (Linking) VI - 100 DP - 2024 Mar TI - A Systematic Review of the Quality of Clinical Practice Guidelines for Chronic Limb-Threatening Ischemia. PG - 81-90 LID - S0890-5096(23)00854-3 [pii] LID - 10.1016/j.avsg.2023.10.025 [doi] AB - BACKGROUND: To assess the quality of clinical practice guidelines (CPGs) for chronic limb-threatening ischemia (CLTI) using the Appraisal of Guidelines for Research and Evaluation II instrument. METHODS: A systematic review of Medline, Embase, and online CPG databases was carried out. Four CPGs on CLTI were identified: Global Vascular Guidelines (GVG), European Society of Cardiology (ESC), American College of Cardiology, and National Institute for Health and Care Excellence guidelines on lower limb peripheral arterial disease. Two independent appraisers analyzed the 4 CPGs using the Appraisal of Guidelines for Research and Evaluation II instrument. CPGs were ranked across 6 domains with 23 items that ranged from 1 (strongly disagree) to 7 (strongly agree). A scaled domain score was calculated as a percentage of the maximum possible score achievable. A domain score of >/=50% and an overall average domain score of >/=80% reflected a CPG of adequate quality recommended for use. RESULTS: GVG had the highest overall score (82.9%), as an average of all domains, and ESC had the lowest score (50.2%). GVG and National Institute for Health and Care Excellence guidelines had all domains scoring >50%, while American College of Cardiology had 5 and ESC had 3. Two domains, rigor of development and applicability, scored the lowest among the CPGs. There was a lack of detail in describing systematic methods used in the literature review, how guidelines were formulated with minimal bias, and the planned procedure for updating the guidelines. Implications of guideline application and monitoring of outcomes after implementations were not explicitly discussed. CONCLUSIONS: The GVG guideline published in 2019 discussing CLTI is assessed to be of high quality and recommended for use. This review helps to improve clinical decision-making and quality of future CPGs for CLTI. CI - Copyright (c) 2023 Elsevier Inc. All rights reserved. FAU - Lee, Adele Hwee Hong AU - Lee AHH AD - Department of Vascular Surgery, Austin Health, Melbourne, Australia. Electronic address: adelehweehonglee.lee@austin.org.au. FAU - Wright, Adele Philippa AU - Wright AP AD - Faculty of Medicine, The University of Melbourne, Melbourne, Australia. FAU - Westcott, Mark J AU - Westcott MJ AD - Department of Vascular Surgery, St Vincent's Hospital, Melbourne, Australia. FAU - Shan, Leonard L AU - Shan LL AD - Department of Vascular Surgery, St Vincent's Hospital, Melbourne, Australia. FAU - Choong, Peter F AU - Choong PF AD - Department of Surgery, The University of Melbourne, Melbourne, Australia. FAU - Davies, Alun H AU - Davies AH AD - Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, London, UK. LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20231218 PL - Netherlands TA - Ann Vasc Surg JT - Annals of vascular surgery JID - 8703941 SB - IM MH - Humans MH - Chronic Limb-Threatening Ischemia MH - Treatment Outcome MH - *Peripheral Arterial Disease/diagnosis/therapy MH - *Cardiology MH - Databases, Factual EDAT- 2023/12/21 00:41 MHDA- 2024/02/19 06:43 CRDT- 2023/12/20 19:29 PHST- 2023/09/02 00:00 [received] PHST- 2023/10/14 00:00 [revised] PHST- 2023/10/21 00:00 [accepted] PHST- 2024/02/19 06:43 [medline] PHST- 2023/12/21 00:41 [pubmed] PHST- 2023/12/20 19:29 [entrez] AID - S0890-5096(23)00854-3 [pii] AID - 10.1016/j.avsg.2023.10.025 [doi] PST - ppublish SO - Ann Vasc Surg. 2024 Mar;100:81-90. doi: 10.1016/j.avsg.2023.10.025. Epub 2023 Dec 18.