PMID- 38124706 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231222 IS - 2673-561X (Electronic) IS - 2673-561X (Print) IS - 2673-561X (Linking) VI - 4 DP - 2023 TI - The effects of upper- vs. lower-body aerobic exercise on perceived pain in individuals with chronic knee pain: a randomised crossover trial. PG - 1277482 LID - 10.3389/fpain.2023.1277482 [doi] LID - 1277482 AB - BACKGROUND AND OBJECTIVES: Some patients with chronic knee pain experience an increase in knee pain following a single bout of exercise involving their knee joint, which can negatively affect exercise adherence and thus result in reduced overall health and lack of disease management. We want to determine whether a single bout of upper-body (UB) aerobic arm-ergometry exercise is effective in reducing the experience of pain in those with chronic knee pain compared with lower-body (LB) aerobic leg ergometry exercise. METHODS: A total of 19 individuals (women = 11, men = 8; age = 63 +/- 8 years; body mass index = 24 +/- 3 kg/m(2)) who suffered from chronic knee pain for >/=3 months took part in this study. Arm-ergometry and cycle-ergometry exercises were performed for 30 min at a moderate intensity, separated by 7 days. Pain intensity was assessed by means of a visual analogue scale (VAS) pre- and post-exercise and for 7 days post-exercise. Pressure pain threshold (PPT) and mechanical detection threshold (MDT) were measured pre- and post-exercise at both local and distal anatomical sites. Data are presented as mean +/- SD. RESULTS: VAS pain was significantly reduced (p = 0.035) at 1 day post-exercise following the UB exercise trial (-1.4 +/- 0.8) when compared with the LB exercise trial (+0.1 +/- 2.1). Both UB and LB exercises were effective in reducing local and distal PPT. MDT responses were heterogeneous, and no differences between the UB and LB exercise conditions were noted. CONCLUSION: An acute bout of upper-body aerobic arm-ergometry exercise evoked a significant decrease in the affected knee joint pain in individuals with chronic knee pain of up to 24 h/1 day post-exercise compared with lower-body aerobic exercise. While the exact mechanisms remain unclear, upper-body exercise may offer a viable, novel therapeutic treatment for patients with chronic knee pain. CI - (c) 2023 Deere, Chowdhury, Tabor, Thompson and Bilzon. FAU - Deere, Rachel AU - Deere R AD - Centre for Clinical Rehabilitation and Exercise Medicine (CREM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for Nutrition and Exercise Metabolism (CNEM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA), University of Bath, Bath, United Kingdom. AD - Centre for Trials Research, Cardiff University, Cardiff, United Kingdom. FAU - Chowdhury, Enhad AU - Chowdhury E AD - Centre for Clinical Rehabilitation and Exercise Medicine (CREM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for Nutrition and Exercise Metabolism (CNEM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA), University of Bath, Bath, United Kingdom. FAU - Tabor, Abby AU - Tabor A AD - Faculty of Health and Applied Sciences, University of West England, Bristol, United Kingdom. FAU - Thompson, Dylan AU - Thompson D AD - Centre for Clinical Rehabilitation and Exercise Medicine (CREM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for Nutrition and Exercise Metabolism (CNEM), Department for Health, University of Bath, Bath, United Kingdom. FAU - Bilzon, James L J AU - Bilzon JLJ AD - Centre for Clinical Rehabilitation and Exercise Medicine (CREM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for Nutrition and Exercise Metabolism (CNEM), Department for Health, University of Bath, Bath, United Kingdom. AD - Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA), University of Bath, Bath, United Kingdom. LA - eng PT - Journal Article DEP - 20231206 PL - Switzerland TA - Front Pain Res (Lausanne) JT - Frontiers in pain research (Lausanne, Switzerland) JID - 9918227269806676 PMC - PMC10731310 OTO - NOTNLM OT - chronic knee pain OT - exercise OT - exercise medicine OT - experimental pain OT - musculoskeletal pain OT - pain management OT - symptomatic pain COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/12/21 06:42 MHDA- 2023/12/21 06:43 PMCR- 2023/12/06 CRDT- 2023/12/21 03:58 PHST- 2023/08/14 00:00 [received] PHST- 2023/11/20 00:00 [accepted] PHST- 2023/12/21 06:43 [medline] PHST- 2023/12/21 06:42 [pubmed] PHST- 2023/12/21 03:58 [entrez] PHST- 2023/12/06 00:00 [pmc-release] AID - 10.3389/fpain.2023.1277482 [doi] PST - epublish SO - Front Pain Res (Lausanne). 2023 Dec 6;4:1277482. doi: 10.3389/fpain.2023.1277482. eCollection 2023.