PMID- 38131217
OWN - NLM
STAT- MEDLINE
DCOM- 20240328
LR  - 20240404
IS  - 2055-5822 (Electronic)
IS  - 2055-5822 (Linking)
VI  - 11
IP  - 2
DP  - 2024 Apr
TI  - Characteristics of patients admitted with heart failure: Insights from the first 
      Malaysian Heart Failure Registry.
PG  - 727-736
LID - 10.1002/ehf2.14608 [doi]
AB  - AIMS: Heart failure (HF) is a growing health problem, yet there are limited data 
      on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry 
      aims to gain insights into the epidemiology, aetiology, management, and outcome 
      of Malaysian patients with HF and identify areas for improvement within the 
      national HF services. METHODS AND RESULTS: The MY-HF Registry is a 3-year 
      prospective, observational study comprising 2717 Malaysian patients admitted for 
      acute HF. We report the description of baseline data at admission and outcomes of 
      index hospitalization of these patients. The mean age was 60.2 +/- 13.6 years, 
      66.8% were male, and 34.3% had de novo HF. Collectively, 55.7% of patients 
      presented with New York Heart Association (NYHA) Class III or IV; ischaemic heart 
      disease was the most frequent aetiology (63.2%). Most admissions (87.3%) occurred 
      via the emergency department, with 13.7% of patients requiring intensive care, 
      and of these, 21.8% needed intubation. The proportion of patients receiving 
      guideline-directed medical therapy increased at discharge (84.2% vs. 93.6%). The 
      median length of stay (LOS) was 5 days, and in-hospital mortality was 2.9%. 
      Predictors of LOS and/or in-hospital mortality were age, NYHA class, estimated 
      glomerular filtration rate, and comorbid anaemia. LOS and in-hospital mortality 
      were similar regardless of ejection fraction. CONCLUSIONS: The MY-HF Registry 
      showed that the HF population in Malaysia is younger, predominantly male, and 
      ischaemic-driven and has good prospects with hospitalization for optimization of 
      treatment. These findings suggest a need to reassess current clinical practice 
      and guide resource allocation to improve patient outcomes.
CI  - (c) 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on 
      behalf of European Society of Cardiology.
FAU - Wan Ahmad, Wan Azman
AU  - Wan Ahmad WA
AUID- ORCID: 0000-0003-4291-0486
AD  - Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, 
      Malaysia.
FAU - Abdul Ghapar, Abdul Kahar
AU  - Abdul Ghapar AK
AD  - Department of Cardiology, Hospital Serdang, Ministry of Health Malaysia, 
      Selangor, Malaysia.
FAU - Zainal Abidin, Hafisyatul Aiza
AU  - Zainal Abidin HA
AD  - Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia.
FAU - Karthikesan, Dharmaraj
AU  - Karthikesan D
AD  - Department of Medicine, Hospital Sultanah Bahiyah, Ministry of Health Malaysia, 
      Kedah, Malaysia.
FAU - Ross, Noel Thomas
AU  - Ross NT
AD  - Department of Medicine, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala 
      Lumpur, Malaysia.
FAU - S K Abdul Kader, Muhamad Ali
AU  - S K Abdul Kader MA
AD  - Department of Medicine, Penang General Hospital, Ministry of Health Malaysia, 
      Penang, Malaysia.
FAU - Loch, Alexander
AU  - Loch A
AD  - Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, 
      Malaysia.
FAU - Mahendran, Kauthaman
AU  - Mahendran K
AD  - Department of General Medicine and Clinical Research Centre, Hospital Melaka, 
      Ministry of Health Malaysia, Melaka, Malaysia.
FAU - Ramli, Ahmad Wazi
AU  - Ramli AW
AD  - Department of Cardiology, Hospital Sultanah Nur Zahirah, Ministry of Health 
      Malaysia, Terengganu, Malaysia.
FAU - Ong, Tiong Kiam
AU  - Ong TK
AD  - Department of Cardiology, Sarawak Heart Centre, Ministry of Health Malaysia, 
      Sarawak, Malaysia.
FAU - Mohd Amin, Nor Hanim
AU  - Mohd Amin NH
AD  - Department of Cardiology, Hospital Raja Permaisuri Bainun, Ministry of Health 
      Malaysia, Perak, Malaysia.
FAU - Lee, Chuey Yan
AU  - Lee CY
AD  - Department of Cardiology, Hospital Sultanah Aminah, Ministry of Health Malaysia, 
      Johor, Malaysia.
FAU - Che Hassan, Hamat Hamdi
AU  - Che Hassan HH
AD  - Department of Cardiology, Hospital Universiti Kebangsaan Malaysia, Ministry of 
      Health Malaysia, Kuala Lumpur, Malaysia.
FAU - Zainal Abidin, Siti Khairani
AU  - Zainal Abidin SK
AD  - Department of General Medicine, Hospital Tengku Ampuan Afzan, Ministry of Health 
      Malaysia, Pahang, Malaysia.
FAU - Liew, Houng Bang
AU  - Liew HB
AD  - Department of Cardiology, Hospital Queen Elizabeth II, Ministry of Health 
      Malaysia, Sabah, Malaysia.
FAU - Ho, Wing Sze
AU  - Ho WS
AD  - Department of Medical Affairs, Novartis Corporation (Malaysia) Sdn Bhd, Petaling 
      Jaya, Malaysia.
FAU - Mohd Ghazi, Azmee
AU  - Mohd Ghazi A
AD  - Department of Cardiology, National Heart Institute of Malaysia, Kuala Lumpur, 
      Malaysia.
LA  - eng
GR  - Novartis Corporation (Malaysia) Sdn Bhd/
PT  - Journal Article
PT  - Observational Study
DEP - 20231222
PL  - England
TA  - ESC Heart Fail
JT  - ESC heart failure
JID - 101669191
SB  - IM
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Aged
MH  - Female
MH  - Prospective Studies
MH  - *Hospitalization
MH  - Length of Stay
MH  - Registries
MH  - *Heart Failure/therapy
PMC - PMC10966232
OTO - NOTNLM
OT  - Acute decompensated heart failure
OT  - Baseline demographics
OT  - Guideline-directed medical therapy utilization
OT  - In-hospital outcome
COIS- H.A.Z.A. serves as a speaker for AstraZeneca, Boehringer Ingelheim, and Novartis; 
      has received grants from the National Heart Centre Singapore, NHAM, Merck, and 
      Sharp and Dohme; and reports consulting relationship with Boehringer Ingelheim. 
      T.K.O. serves as a speaker for Bayer, Boehringer Ingelheim, and Novartis and 
      reports consulting relationships with AstraZeneca, Boehringer Ingelheim, and Novo 
      Nordisk. W.S.H. is an employee of Novartis Corporation (Malaysia) Sdn Bhd. None 
      of the authors have any direct conflicts of interest related to this article.
EDAT- 2023/12/22 06:43
MHDA- 2024/03/28 06:46
PMCR- 2023/12/22
CRDT- 2023/12/22 05:30
PHST- 2023/10/25 00:00 [revised]
PHST- 2023/06/14 00:00 [received]
PHST- 2023/11/16 00:00 [accepted]
PHST- 2024/03/28 06:46 [medline]
PHST- 2023/12/22 06:43 [pubmed]
PHST- 2023/12/22 05:30 [entrez]
PHST- 2023/12/22 00:00 [pmc-release]
AID - EHF214608 [pii]
AID - 10.1002/ehf2.14608 [doi]
PST - ppublish
SO  - ESC Heart Fail. 2024 Apr;11(2):727-736. doi: 10.1002/ehf2.14608. Epub 2023 Dec 
      22.