PMID- 38139637 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231225 IS - 1424-8220 (Electronic) IS - 1424-8220 (Linking) VI - 23 IP - 24 DP - 2023 Dec 13 TI - Simulation and Analysis of Anodized Aluminum Oxide Membrane Degradation. LID - 10.3390/s23249792 [doi] LID - 9792 AB - Microelectromechanical systems (MEMS)-based filter with microchannels enables the removal of various microorganisms, including viruses and bacteria, from fluids. Membranes with porous channels can be used as filtration interfaces in MEMS hemofilters or mini-dialyzers. The main problems associated with the filtration process are optimization of membrane geometry and fouling. A nanoporous aluminum oxide membrane was fabricated using an optimized two-step anodization process. Computational strength modeling and analysis of the membrane with specified parameters were performed using the ANSYS structural module. A fuzzy simulation was performed for the numerical analysis of flux through the membrane. The membrane was then incorporated with the prototype for successive filtration. The fluid flux and permeation analysis of the filtration process have been studied. Scanning electron microscope (SEM) micrographs of membranes have been obtained before and after the filtration cycles. The SEM results indicate membrane fouling after multiple cycles, and thus the flux is affected. This type of fabricated membrane and setup are suitable for the separation and purification of various fluids. However, after several filtration cycles, the membrane was degraded. It requires a prolonged chemical cleaning. High-density water has been used for filtration purposes, so this MEMS-based filter can also be used as a mini-dialyzer and hemofilter in various applications for filtration. Such a demonstration also opens up a new strategy for maximizing filtration efficiency and reducing energy costs for the filtration process by using a layered membrane setup. FAU - Manzoor, Saher AU - Manzoor S AUID- ORCID: 0000-0002-2947-9946 AD - Department of Electronics, Institute of Physics, GC University Lahore, Lahore 54000, Pakistan. FAU - Qasim, Faheem AU - Qasim F AD - Department of Electronics, Institute of Physics, GC University Lahore, Lahore 54000, Pakistan. FAU - Ashraf, Muhammad Waseem AU - Ashraf MW AUID- ORCID: 0000-0002-7776-2746 AD - Department of Electronics, Institute of Physics, GC University Lahore, Lahore 54000, Pakistan. FAU - Tayyaba, Shahzadi AU - Tayyaba S AUID- ORCID: 0000-0003-4703-5852 AD - Department of Information Sciences, Division of Science and Technology, University of Education, Township Campus, Lahore 54000, Pakistan. FAU - Tariq, Nimra AU - Tariq N AUID- ORCID: 0000-0002-9934-8941 AD - Department of Physics and Mathematics, Faculty of Sciences, The Superior University Lahore, Lahore 54000, Pakistan. FAU - Herrera-May, Agustin L AU - Herrera-May AL AUID- ORCID: 0000-0002-7373-9258 AD - Micro and Nanotechnology Research Center, Universidad Veracruzana, Boca del Rio 94294, Mexico. FAU - Delgado-Alvarado, Enrique AU - Delgado-Alvarado E AUID- ORCID: 0000-0002-6354-5222 AD - Micro and Nanotechnology Research Center, Universidad Veracruzana, Boca del Rio 94294, Mexico. LA - eng PT - Journal Article DEP - 20231213 PL - Switzerland TA - Sensors (Basel) JT - Sensors (Basel, Switzerland) JID - 101204366 SB - IM PMC - PMC10747657 OTO - NOTNLM OT - anodic aluminum oxide OT - filtration OT - membrane degradation OT - two-step anodization COIS- The authors declare no conflict of interest. EDAT- 2023/12/23 12:44 MHDA- 2023/12/23 12:45 PMCR- 2023/12/13 CRDT- 2023/12/23 01:23 PHST- 2023/10/06 00:00 [received] PHST- 2023/12/08 00:00 [revised] PHST- 2023/12/09 00:00 [accepted] PHST- 2023/12/23 12:45 [medline] PHST- 2023/12/23 12:44 [pubmed] PHST- 2023/12/23 01:23 [entrez] PHST- 2023/12/13 00:00 [pmc-release] AID - s23249792 [pii] AID - sensors-23-09792 [pii] AID - 10.3390/s23249792 [doi] PST - epublish SO - Sensors (Basel). 2023 Dec 13;23(24):9792. doi: 10.3390/s23249792.