PMID- 38144719 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231225 IS - 2590-1575 (Electronic) IS - 2590-1575 (Linking) VI - 20 DP - 2023 Dec 30 TI - Measurement of polychlorinated biphenyls in different high consumption canned foods, using the QuEChERS/GC-MS method. PG - 100957 LID - 10.1016/j.fochx.2023.100957 [doi] LID - 100957 AB - Polychlorinated biphenyls (PCBs) are organic pollutants containing chlorine, which can be carcinogenic to humans. The current research focused on the heart risk and determination of PCBs levels in canned foods using the modified QuEChERS (fast, easy, cheap, effective, resistant and safe) method and gas chromatograph/mass spectrometer (GC-MS) technique. In this study, LOD (limit of detection), LOQ (limit of quantification), and recovery ranged from 0.06 to 0.32, 0.18 to 1.07 ng/g, and 97.05 to 102.5 %, respectively. In canned foods, the highest median of PCBs was PCB 52 (0.27 +/- 0.20 ng/g fat) and the lowest median were PCB 28 and 138 (not detected in samples). Also, the maximum median of PCB 28, 52, 101, 138, 153, and 180 were detected in eggplant samples (0.06 ng/g), haricot samples (0.49 ng/g), eggplant samples (0.36 ng/g), eggplant samples (0.19 ng/g), eggplant samples (0.11 ng/g) and lentiform samples (0.66 ng/g), respectively. The median PCBs levels of oral exposure were estimated to be in the range of 9.80E-07to 4.30E-05 ng/g.d for all population groups, which were meaningfully lesser than the Tolerable daily intake value. The Monte Carlo simulation (MCS) outcomes indicated that the rank order of PCBs in adults based on incremental lifetime cancer risk (ILCR) was Lentiform (7.05E-8) > canned fish (5.73E-8) > Eggplant (5.38E-8) > Haricot (4.33E-8) > pasta source (2.06E-8); and in children was Lentiform (3.40E-7) > canned fish (2.72E-7) > Eggplant (2.44E-7) > Haricot (2.06E-7) > pasta source (9.83E-8). The median values of the ILCR induced oral exposure for all groups were within safe limits (lower than 10(-6)). The heat map and multivariate principal component analysis (PCA) showed significantly different contributions of PCBs profile in samples as the PCA axis scores were correlated with the type of cans. Based on the obtained outcomes, it can be concluded that the PCBs of canned food do not potential health risks to Iranian consumers. CI - (c) 2023 The Authors. FAU - Vali Mohammadi, Faezeh AU - Vali Mohammadi F AD - Food Hygiene and Safety, School of Public Health, Qazvin University of Medical Sciences, Qazvin, Iran. FAU - Qajarbeygi, Peyman AU - Qajarbeygi P AD - Health Products Safety Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. FAU - Shariatifar, Nabi AU - Shariatifar N AD - Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. AD - Food Safety Research Center (salt), Semnan University of Medical Sciences, Semnan, Iran. FAU - Mahmoudi, Razzagh AU - Mahmoudi R AD - Food Hygiene and Safety, School of Public Health, Qazvin University of Medical Sciences, Qazvin, Iran. FAU - Arabameri, Majid AU - Arabameri M AD - Food Safety Research Center (salt), Semnan University of Medical Sciences, Semnan, Iran. LA - eng PT - Journal Article DEP - 20231021 PL - Netherlands TA - Food Chem X JT - Food chemistry: X JID - 101751436 PMC - PMC10740129 OTO - NOTNLM OT - Canned foods OT - GC-MS OT - Health risk assessment OT - Polychlorinated biphenyls OT - QuEChERS COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/12/25 06:43 MHDA- 2023/12/25 06:44 PMCR- 2023/10/21 CRDT- 2023/12/25 04:41 PHST- 2023/05/27 00:00 [received] PHST- 2023/10/12 00:00 [revised] PHST- 2023/10/21 00:00 [accepted] PHST- 2023/12/25 06:44 [medline] PHST- 2023/12/25 06:43 [pubmed] PHST- 2023/12/25 04:41 [entrez] PHST- 2023/10/21 00:00 [pmc-release] AID - S2590-1575(23)00400-5 [pii] AID - 100957 [pii] AID - 10.1016/j.fochx.2023.100957 [doi] PST - epublish SO - Food Chem X. 2023 Oct 21;20:100957. doi: 10.1016/j.fochx.2023.100957. eCollection 2023 Dec 30.