PMID- 38150850 OWN - NLM STAT- MEDLINE DCOM- 20240428 LR - 20240502 IS - 1578-1275 (Electronic) IS - 0212-6567 (Print) IS - 0212-6567 (Linking) VI - 56 IP - 5 DP - 2024 May TI - [New tools for medication review: DRP in patients treatment with proton pump inhibitors]. PG - 102836 LID - S0212-6567(23)00269-X [pii] LID - 10.1016/j.aprim.2023.102836 [doi] LID - 102836 AB - OBJECTIVE: To analyze, using the medication review program, Revisem(R), the prevalence of drug-related problems (DRP) in patients in the province of Valencia who were on active treatment with proton pump inhibitors (PPI) in 2022. DESIGN: Descriptive and retrospective observational study. MATERIAL AND METHODS: The pharmacotherapeutic history of 295 patients was analyzed following the criteria proposed by the Pharmaceutical Care Network Europe, using the Revisem(R) digital platform of the Muy Ilustre Colegio Oficial de Farmaceuticos (MICOF). RESULTS: The mean age of the patients was 81.8 +/- 11.1 years and 66.4% were women. At least one DRP was detected in 97.3% of patients. 46.9% of the DRP analyzed were interactions, of which 29.7% involved a PPI, with omeprazole being the most frequent. DRPs with PPI are significantly related to certain patient conditions and pharmacological groups, such as female sex, age over 54 years and polypharmacy. CONCLUSIONS: The application of the Revisem(R) digital platform allows the detection of a high prevalence of DRP at the provincial level. The application of new technological tools to detect the prevalence of DRP is essential to optimize patient treatments. CI - Copyright (c) 2023 The Authors. Publicado por Elsevier Espana S.L.U. All rights reserved. FAU - Gutierrez-Igual, Salvador AU - Gutierrez-Igual S AD - Servicios Asistenciales Farmaceuticos y Formacion, Muy Ilustre Colegio Oficial de Farmaceuticos de Valencia (MICOF), Valencia, Espana; Departamento de Farmacologia, Universidad de Valencia (UV), Burjassot, Espana. Electronic address: salvador.gutierrez@micof.es. FAU - Lucas-Dominguez, Rut AU - Lucas-Dominguez R AD - UISYS, Departamento de Historia de la Ciencia y Documentacion, Facultad de Medicina y Odontologia, Universidad de Valencia (UV), Valencia, Espana; Unidad asociada al Instituto Interuniversitario de Investigacion Avanzada sobre Evaluacion de la Ciencia y la Universidad (INAECU), UC3M-UAM3, Madrid, Espana; CIBERONC, Valencia, Espana. Electronic address: rut.lucas@uv.es. FAU - Marti Rodrigo, Alberto AU - Marti Rodrigo A AD - Servicios Asistenciales Farmaceuticos y Formacion, Muy Ilustre Colegio Oficial de Farmaceuticos de Valencia (MICOF), Valencia, Espana. FAU - Romero Crespo, Isabel AU - Romero Crespo I AD - Servicios Asistenciales Farmaceuticos y Formacion, Muy Ilustre Colegio Oficial de Farmaceuticos de Valencia (MICOF), Valencia, Espana. FAU - Montesinos Mezquita, M Carmen AU - Montesinos Mezquita MC AD - Departamento de Farmacologia, Universidad de Valencia (UV), Burjassot, Espana; Equipo Estudios de Bioactividad, Instituto Interuniversitario de Reconocimiento Molecular y Desarrollo Tecnologico (IDM). Universidad Politecnica de Valencia (UPV). Universidad de Valencia (UV), Valencia, Espana. LA - spa PT - English Abstract PT - Journal Article PT - Observational Study TT - Nuevas herramientas para la revision de la medicacion: PRM en pacientes en tratamiento con inhibidores de la bomba de protones. DEP - 20231226 PL - Spain TA - Aten Primaria JT - Atencion primaria JID - 9111075 RN - 0 (Proton Pump Inhibitors) SB - IM MH - Humans MH - *Proton Pump Inhibitors/therapeutic use MH - Female MH - Male MH - Retrospective Studies MH - Aged, 80 and over MH - Aged MH - Middle Aged MH - Drug-Related Side Effects and Adverse Reactions/epidemiology PMC - PMC11058877 OTO - NOTNLM OT - Community pharmacy OT - Drug Related Problem OT - Farmacia comunitaria OT - Inhibidor de la bomba de protones OT - Omeprazol OT - Omeprazole OT - Plataforma digital Revisem(R) OT - Problema relacionado con la medicacion OT - Proton Pump Inhibitor OT - Revisem(R) digital platform EDAT- 2023/12/28 00:42 MHDA- 2024/04/29 01:00 PMCR- 2023/12/26 CRDT- 2023/12/27 18:06 PHST- 2023/10/16 00:00 [received] PHST- 2023/11/09 00:00 [revised] PHST- 2023/11/13 00:00 [accepted] PHST- 2024/04/29 01:00 [medline] PHST- 2023/12/28 00:42 [pubmed] PHST- 2023/12/27 18:06 [entrez] PHST- 2023/12/26 00:00 [pmc-release] AID - S0212-6567(23)00269-X [pii] AID - 102836 [pii] AID - 10.1016/j.aprim.2023.102836 [doi] PST - ppublish SO - Aten Primaria. 2024 May;56(5):102836. doi: 10.1016/j.aprim.2023.102836. Epub 2023 Dec 26.