PMID- 38151350
OWN - NLM
STAT- MEDLINE
DCOM- 20231229
LR  - 20240106
IS  - 0371-0874 (Print)
IS  - 0371-0874 (Linking)
VI  - 75
IP  - 6
DP  - 2023 Dec 25
TI  - [Traditional Chinese medicine used as anti-aging agent by targeting nuclear 
      factor erythroid 2-related factor 2 signaling pathway].
PG  - 877-886
AB  - The imbalance of redox homeostasis is a major characteristic of aging and 
      contributes to the pathogenesis of various aging-related diseases. As a 
      regulatory hub of redox homeostasis, nuclear factor erythroid 2-related factor 2 
      (NRF2) can attenuate oxidative stress by activating the transcription of many 
      antioxidant enzymes. China is the birthplace of traditional Chinese medicine 
      (TCM) which has been wildly used as medicine for thousands of years. Recently, 
      TCM as anti-aging medicine has attracted enormous attention. Focusing on the NRF2 
      signaling pathway, this paper summarizes the correlation between various 
      anti-aging TCM and the NRF2 signaling, and discusses the common key mechanisms by 
      which TCM slows the aging process by targeting the NRF2 signaling network.
FAU - Xu, Jia-Yi
AU  - Xu JY
AD  - National and Local Joint Engineering Research Center for Biological Diagnosis and 
      Treatment, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, 
      China.
FAU - Yan, Liang-Wen
AU  - Yan LW
AD  - National and Local Joint Engineering Research Center for Biological Diagnosis and 
      Treatment, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, 
      China.
FAU - Tang, Shen-Kang
AU  - Tang SK
AD  - National and Local Joint Engineering Research Center for Biological Diagnosis and 
      Treatment, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, 
      China.
AD  - Department of Oncology, Affiliated Hospital of Shaanxi University of Chinese 
      Medicine, Xianyang 712000, China.
FAU - Liu, Peng-Fei
AU  - Liu PF
AD  - National and Local Joint Engineering Research Center for Biological Diagnosis and 
      Treatment, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, 
      China. liupengfei@xjtu.edu.cn.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Sheng Li Xue Bao
JT  - Sheng li xue bao : [Acta physiologica Sinica]
JID - 20730130R
RN  - 0 (NF-E2-Related Factor 2)
SB  - IM
MH  - *Medicine, Chinese Traditional
MH  - *NF-E2-Related Factor 2/metabolism
MH  - Oxidative Stress
MH  - Signal Transduction
EDAT- 2023/12/28 00:42
MHDA- 2023/12/29 06:43
CRDT- 2023/12/27 21:53
PHST- 2023/12/29 06:43 [medline]
PHST- 2023/12/28 00:42 [pubmed]
PHST- 2023/12/27 21:53 [entrez]
PST - ppublish
SO  - Sheng Li Xue Bao. 2023 Dec 25;75(6):877-886.