PMID- 38151818
OWN - NLM
STAT- MEDLINE
DCOM- 20240427
LR  - 20240427
IS  - 1554-527X (Electronic)
IS  - 0736-0266 (Linking)
VI  - 42
IP  - 6
DP  - 2024 Jun
TI  - Impact of preoperative clinical state on 2-year clinical outcomes following 
      degenerative lumbar scoliosis surgery.
PG  - 1335-1342
LID - 10.1002/jor.25780 [doi]
AB  - To assess the preoperative clinical state's impact on clinical outcomes after 
      surgery for degenerative lumbar scoliosis (DLS) based on the minimal clinically 
      important difference (MCID). Preoperative and follow-up (FU) scores in 
      each Scoliosis Research Society-22 (SRS-22) domain were compared with age- and 
      sex-matched normative references. At baseline, patients were classified by 
      differences from normative values in four groups: Worst, Severe, Poor, and 
      Moderate. At 2 years postoperative FU, patients were divided into four groups 
      (Worst Severe Poor Asymptomatic) based on the difference in MCID between 
      postoperative and normal values. The changes in MCID were considered as the 
      criterion for surgical efficacy. In addition, we calculated the classification of 
      preoperative and FU clinical symptom severity in each domain in same patient. The 
      distinction among curve types was also performed based on the SRS-Schwab 
      classification. A total of 123 patients were included. During FU, patients with 
      more severe preoperative clinical symptoms were more likely to achieve clinical 
      changes (>1 MCID, p < 0.05), but the rate of reaching "asymptomatic" was lower 
      (p < 0.05). Kendall's tau-b correlation analysis found that preoperative clinical 
      severity was correlated with clinical changes category in Activity 
      (Tau-b = 0.252; p = 0.002), Pain (Tau-b = 0.230; p = 0.005), Appearance 
      (Tau-b = 0.307; p < 0.001), and Mental (Tau-b = 0.199; p = 0.016), and it also 
      was correlated with FU clinical severity in Activity (Tau-b = 0.173; p = 0.023), 
      Pain (Tau-b = 0.280; p < 0.001), and Mental (Tau-b = 0.349; p < 0.001). There was 
      a correlation between preoperative clinical severity and FU SRS-22 score 
      outcomes. Patients with severe preoperative clinical symptoms can experience 
      better treatment outcomes during FU, but it is also more difficult to recover to 
      the normal reference.
CI  - (c) 2024 Orthopaedic Research Society.
FAU - Yuan, Lei
AU  - Yuan L
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, China.
AD  - Beijing Key Laboratory of Spinal Disease Research, Peking University Third 
      Hospital, Beijing, China.
AD  - Engineering Research Center of Bone and Joint Precision Medicine, Ministry of 
      Education, Peking University Third Hospital, Beijing, China.
FAU - Liu, Yinhao
AU  - Liu Y
AUID- ORCID: 0009-0008-7220-9096
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, China.
AD  - Beijing Key Laboratory of Spinal Disease Research, Peking University Third 
      Hospital, Beijing, China.
AD  - Engineering Research Center of Bone and Joint Precision Medicine, Ministry of 
      Education, Peking University Third Hospital, Beijing, China.
AD  - Peking University Health Science Center, Beijing, China.
FAU - Zeng, Yan
AU  - Zeng Y
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, China.
AD  - Beijing Key Laboratory of Spinal Disease Research, Peking University Third 
      Hospital, Beijing, China.
AD  - Engineering Research Center of Bone and Joint Precision Medicine, Ministry of 
      Education, Peking University Third Hospital, Beijing, China.
FAU - Chen, Zhongqiang
AU  - Chen Z
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, China.
AD  - Beijing Key Laboratory of Spinal Disease Research, Peking University Third 
      Hospital, Beijing, China.
AD  - Engineering Research Center of Bone and Joint Precision Medicine, Ministry of 
      Education, Peking University Third Hospital, Beijing, China.
FAU - Li, Weishi
AU  - Li W
AD  - Department of Orthopedics, Peking University Third Hospital, Beijing, China.
AD  - Beijing Key Laboratory of Spinal Disease Research, Peking University Third 
      Hospital, Beijing, China.
AD  - Engineering Research Center of Bone and Joint Precision Medicine, Ministry of 
      Education, Peking University Third Hospital, Beijing, China.
LA  - eng
GR  - BYSYZD2022028/Key Clinical Projects of Peking University Third Hospital/
GR  - 82272540/National Natural Science Foundation of China/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20240112
PL  - United States
TA  - J Orthop Res
JT  - Journal of orthopaedic research : official publication of the Orthopaedic 
      Research Society
JID - 8404726
SB  - IM
MH  - Humans
MH  - *Scoliosis/surgery
MH  - Female
MH  - Male
MH  - Aged
MH  - Middle Aged
MH  - *Lumbar Vertebrae/surgery
MH  - Treatment Outcome
MH  - Minimal Clinically Important Difference
MH  - Retrospective Studies
MH  - Preoperative Period
OTO - NOTNLM
OT  - clinical outcomes
OT  - degenerative lumbar scoliosis
OT  - health-related quality of life
OT  - minimal clinically important difference
OT  - preoperative clinical status
EDAT- 2023/12/28 06:42
MHDA- 2024/04/27 09:54
CRDT- 2023/12/28 00:52
PHST- 2023/12/10 00:00 [revised]
PHST- 2023/08/02 00:00 [received]
PHST- 2023/12/18 00:00 [accepted]
PHST- 2024/04/27 09:54 [medline]
PHST- 2023/12/28 06:42 [pubmed]
PHST- 2023/12/28 00:52 [entrez]
AID - 10.1002/jor.25780 [doi]
PST - ppublish
SO  - J Orthop Res. 2024 Jun;42(6):1335-1342. doi: 10.1002/jor.25780. Epub 2024 Jan 12.