PMID- 38155115
OWN - NLM
STAT- MEDLINE
DCOM- 20240101
LR  - 20240102
IS  - 2313-4607 (Electronic)
IS  - 2304-8336 (Linking)
VI  - 28
DP  - 2023 Dec
TI  - TNF-alpha AND IONIZING RADIATION: THE ROLE IN THE PATHOGENESIS AND TREATMENT OF 
      PLASMA CELL MYELOMA (review).
PG  - 65-74
LID - 10.33145/2304-8336-2023-28-65-74 [doi]
AB  - The review presents data from the literature on the role of Tumor necrosis 
      factor-alpha (TNF-alpha) and ionizing radiation (IR) in the pathogenesis and treatment of 
      plasma cell myeloma (PCM). There was analyzed disturbance of regulation of 
      functioning of this cytokine, which affects the interaction of the immune system 
      with substrate plasma cells under the influence of negative external factors, 
      including ionizing radiation IR. Modern directions of therapy of this disease 
      using the latest technologies are presented, in particular CAR T-cell therapy, 
      which will allow to optimize in the future treatment of this disease and, thus, 
      improve the quality and life expectancy of PCM patients.
CI  - T. F. Liubarets.
FAU - Liubarets, T F
AU  - Liubarets TF
AD  - Bogomolets National Medical University, 13 Tarasa Shevchenko Blvd, Kyiv, 01601, 
      Ukraine.
LA  - eng
LA  - ukr
PT  - Journal Article
PT  - Review
TT  - TNF-alpha capital TE, Cyrilliccapital A, Cyrillic capital I, Ukrainiancapital O, Cyrilliccapital EN, Cyrilliccapital I, Ukrainiancapital ZE, Cyrilliccapital U, Cyrilliccapital YU, Cyrilliccapital CHE, Cyrilliccapital IE, Cyrillic capital VE, Cyrilliccapital I, Cyrilliccapital PE, Cyrilliccapital ER, Cyrilliccapital O, Cyrilliccapital EM, Cyrilliccapital I, Ukrainiancapital EN, Cyrilliccapital YU, Cyrilliccapital VE, Cyrilliccapital A, Cyrilliccapital EN, Cyrilliccapital EN, Cyrilliccapital YA, Cyrillic: capital ER, Cyrilliccapital O, Cyrilliccapital EL, Cyrilliccapital SOFT sign, Cyrillic capital VE, Cyrillic capital PE, Cyrilliccapital A, Cyrilliccapital TE, Cyrilliccapital O, Cyrilliccapital GHE, Cyrilliccapital IE, Cyrilliccapital EN, Cyrilliccapital IE, Cyrilliccapital ZE, Cyrilliccapital I, Ukrainian capital I, Ukrainian capital EL, Cyrilliccapital I, Ukrainiancapital KA, Cyrilliccapital U, Cyrilliccapital VE, Cyrilliccapital A, Cyrilliccapital EN, Cyrilliccapital EN, Cyrilliccapital I, Ukrainian capital PE, Cyrilliccapital EL, Cyrilliccapital A, Cyrilliccapital ZE, Cyrilliccapital EM, Cyrilliccapital O, Cyrilliccapital KA, Cyrilliccapital EL, Cyrilliccapital I, Ukrainiancapital TE, Cyrilliccapital I, Cyrilliccapital EN, Cyrilliccapital EN, Cyrilliccapital O, Cyrilliccapital YI, Ukrainian 
      capital EM, Cyrilliccapital I, Ukrainiancapital JE, Ukrainiancapital EL, Cyrilliccapital O, Cyrilliccapital EM, Cyrilliccapital I, Cyrillic (small o, Cyrillicsmall ghe, Cyrillicsmall el, Cyrillicsmall ya, Cyrillicsmall de, Cyrillic small el, Cyrillicsmall i, Ukrainiansmall te, Cyrillicsmall ie, Cyrillicsmall er, Cyrillicsmall a, Cyrillicsmall te, Cyrillicsmall u, Cyrillicsmall er, Cyrillicsmall i, Cyrillic).
PL  - Ukraine
TA  - Probl Radiac Med Radiobiol
JT  - Problemy radiatsiinoi medytsyny ta radiobiolohii
JID - 101560511
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 0 (Cytokines)
SB  - IM
MH  - Humans
MH  - *Tumor Necrosis Factor-alpha
MH  - *Multiple Myeloma/etiology/therapy/pathology
MH  - Cytokines
MH  - Radiation, Ionizing
OTO - NOTNLM
OT  - CAR T-cell therapy
OT  - TNF-alpha
OT  - cytokines
OT  - plasma cell myeloma
EDAT- 2023/12/29 00:42
MHDA- 2024/01/02 11:42
CRDT- 2023/12/28 22:52
PHST- 2023/05/02 00:00 [received]
PHST- 2024/01/02 11:42 [medline]
PHST- 2023/12/29 00:42 [pubmed]
PHST- 2023/12/28 22:52 [entrez]
AID - 10.33145/2304-8336-2023-28-65-74 [doi]
PST - ppublish
SO  - Probl Radiac Med Radiobiol. 2023 Dec;28:65-74. doi: 
      10.33145/2304-8336-2023-28-65-74.