PMID- 38156856
OWN - NLM
STAT- MEDLINE
DCOM- 20240103
LR  - 20240305
IS  - 2476-762X (Electronic)
IS  - 1513-7368 (Print)
IS  - 1513-7368 (Linking)
VI  - 24
IP  - 12
DP  - 2023 Dec 1
TI  - Smokeless Tobacco Use and Its Association with Type 2 Diabetes: A Case Control 
      Study.
PG  - 4209-4217
LID - 90929 [pii]
LID - 10.31557/APJCP.2023.24.12.4209 [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder 
      characterized by hyperglycemia and insulin resistance. Its incidence is 
      increasing globally, with a significant impact on public health. Smokeless 
      tobacco (SLT) is a form of tobacco consumption that has been associated with 
      various health risks, including potential effects on glucose homeostasis. This 
      case-control study aimed to investigate the association between SLT use and T2DM. 
      Additionally, the study aimed to assess the relationship of age, gender, 
      socioeconomic status (SES), body mass index (BMI), family history of diabetes, 
      physical activity, and periodontal status with T2DM participants. METHODS: The 
      study was conducted over 24 months and included 82 T2DM cases and 164 
      non-diabetic controls. Demographic data, tobacco use, medical history, oral 
      hygiene habits, BMI, and periodontal status were collected through a 
      self-administered questionnaire and interviews. Statistical analyses were 
      performed using Statistical Package for Social Sciences (SPSS) for Windows 26.0 
      (SPSS, Inc. Chicago, Illinois). RESULTS: The majority of T2DM cases were in the 
      age group of 31-50 years, and there was a significant association between gender 
      and T2DM, with more males being diabetic. There was no significant association 
      between SES and diabetes. Obesity was found to be a significant risk factor for 
      T2DM. Among SLT users, gutkha was the most commonly used product. SLT use was 
      significantly associated with T2DM. Family history of diabetes and physical 
      inactivity were also significantly associated with diabetes. CONCLUSION: The 
      study suggests that SLT use is a risk factor for T2DM and may be associated with 
      increased diabetes risk. Further research is warranted to understand the 
      underlying mechanisms and potential interventions to reduce the impact of SLT on 
      diabetes risk.
FAU - Sawane, Harshawardhan
AU  - Sawane H
AD  - Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, 
      Pimpri, Pune Maharashtra, Dr D Y Patil Vidyapeeth Pimpri, Pune Maharashtra, 
      India.
FAU - Rajpurohit, Ladusingh
AU  - Rajpurohit L
AD  - Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, 
      Pimpri, Pune Maharashtra, Dr D Y Patil Vidyapeeth Pimpri, Pune Maharashtra, 
      India.
FAU - Sonawane, Shrutika
AU  - Sonawane S
AD  - Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, 
      Pimpri, Pune Maharashtra, Dr D Y Patil Vidyapeeth Pimpri, Pune Maharashtra, 
      India.
FAU - Kharat, Priyanka
AU  - Kharat P
AD  - Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, 
      Pimpri, Pune Maharashtra, Dr D Y Patil Vidyapeeth Pimpri, Pune Maharashtra, 
      India.
FAU - Mathur, Anmol
AU  - Mathur A
AD  - Department of Public Health Dentistry, Dr D Y Patil Dental College and Hospital, 
      Pimpri, Pune Maharashtra, Dr D Y Patil Vidyapeeth Pimpri, Pune Maharashtra, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20231201
PL  - Thailand
TA  - Asian Pac J Cancer Prev
JT  - Asian Pacific journal of cancer prevention : APJCP
JID - 101130625
SB  - IM
MH  - Male
MH  - Humans
MH  - Adult
MH  - Middle Aged
MH  - *Tobacco, Smokeless/adverse effects
MH  - Case-Control Studies
MH  - *Diabetes Mellitus, Type 2/epidemiology/etiology
MH  - Tobacco Use/adverse effects/epidemiology
MH  - *Tobacco Use Disorder/epidemiology
PMC - PMC10909092
OTO - NOTNLM
OT  - Diabetes Mellitus
OT  - India
OT  - Type 2
OT  - case-control studies
OT  - smokeless tobacco
EDAT- 2024/01/02 11:45
MHDA- 2024/01/03 09:42
PMCR- 2023/03/01
CRDT- 2023/12/29 08:54
PHST- 2023/07/28 00:00 [received]
PHST- 2024/01/03 09:42 [medline]
PHST- 2024/01/02 11:45 [pubmed]
PHST- 2023/12/29 08:54 [entrez]
PHST- 2023/03/01 00:00 [pmc-release]
AID - 90929 [pii]
AID - 10.31557/APJCP.2023.24.12.4209 [doi]
PST - epublish
SO  - Asian Pac J Cancer Prev. 2023 Dec 1;24(12):4209-4217. doi: 
      10.31557/APJCP.2023.24.12.4209.