PMID- 38158854
OWN - NLM
STAT- MEDLINE
DCOM- 20240315
LR  - 20240403
IS  - 1600-051X (Electronic)
IS  - 0303-6979 (Linking)
VI  - 51
IP  - 4
DP  - 2024 Apr
TI  - Association between polycyclic aromatic hydrocarbons and periodontitis: Results 
      from a large population-based study.
PG  - 441-451
LID - 10.1111/jcpe.13919 [doi]
AB  - AIM: To explore the association between polycyclic aromatic hydrocarbons (PAHs) 
      (measured using urinary metabolites) and periodontitis using data from the 
      National Health and Nutrition Examination Survey 2009-2014. MATERIALS AND 
      METHODS: Weighted binary logistic regression, Bayesian kernel machine regression 
      (BKMR) and weighted quantile sum (WQS) regression were used to evaluate 
      independent and joint associations between the six urinary monohydroxylated 
      metabolites of PAHs (OH-PAHs) and periodontitis. RESULTS: In all, 3413 
      participants were included in this study. All six urinary OH-PAHs were present at 
      higher levels in the periodontitis group compared with the non-periodontitis 
      group (p < .001). Fully adjusted multivariable logistic regressions showed 
      positive associations between the six urinary OH-PAHs and periodontitis 
      (p < .05). Higher concentrations of OH-PAHs were also positively associated with 
      attachment loss, periodontal pocket depth (PPD) and the number of tooth loss. 
      BKMR and WQS regression yielded similar positive associations between OH-PAH 
      mixtures and periodontitis. CONCLUSIONS: PAHs and their mixture are positively 
      associated with periodontitis, which may provide novel insights into 
      periodontitis prevention from an environmental exposure perspective.
CI  - (c) 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Wu, Yuxuan
AU  - Wu Y
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - Yang, Han
AU  - Yang H
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - Jin, Weiqiu
AU  - Jin W
AD  - Department of Periodontology, Nanjing Stomatological Hospital, Affiliated 
      Hospital of Medical School, Nanjing University, Nanjing, China.
FAU - Wu, Yuying
AU  - Wu Y
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - Yu, Yiming
AU  - Yu Y
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - Chen, Qiansi
AU  - Chen Q
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - He, Baochang
AU  - He B
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
FAU - Yan, Fuhua
AU  - Yan F
AUID- ORCID: 0000-0002-6963-3530
AD  - Department of Periodontology, Nanjing Stomatological Hospital, Affiliated 
      Hospital of Medical School, Nanjing University, Nanjing, China.
FAU - Li, Yanfen
AU  - Li Y
AD  - Department of Periodontology, Nanjing Stomatological Hospital, Affiliated 
      Hospital of Medical School, Nanjing University, Nanjing, China.
FAU - Chen, Fa
AU  - Chen F
AUID- ORCID: 0009-0007-1184-7839
AD  - Department of Epidemiology and Health Statistics, School of Public Health, Fujian 
      Medical University, Fuzhou, China.
AD  - Clinical Research Unit, The Second Affiliated Hospital, Fujian Medical 
      University, Quanzhou, China.
LA  - eng
GR  - 82301071/National Natural Science Foundation of China/
GR  - XRCZX2018001/the High-level Talents research Start-up Project of Fujian Medical 
      University/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20231230
PL  - United States
TA  - J Clin Periodontol
JT  - Journal of clinical periodontology
JID - 0425123
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
SB  - IM
MH  - Humans
MH  - Bayes Theorem
MH  - Nutrition Surveys
MH  - *Periodontitis/epidemiology
MH  - Periodontal Pocket
MH  - *Polycyclic Aromatic Hydrocarbons/adverse effects
OTO - NOTNLM
OT  - National Health and Nutrition Examination Survey
OT  - periodontitis
OT  - polycyclic aromatic hydrocarbons
EDAT- 2024/01/02 11:44
MHDA- 2024/03/15 06:44
CRDT- 2023/12/30 05:53
PHST- 2023/11/27 00:00 [revised]
PHST- 2023/05/08 00:00 [received]
PHST- 2023/12/01 00:00 [accepted]
PHST- 2024/03/15 06:44 [medline]
PHST- 2024/01/02 11:44 [pubmed]
PHST- 2023/12/30 05:53 [entrez]
AID - 10.1111/jcpe.13919 [doi]
PST - ppublish
SO  - J Clin Periodontol. 2024 Apr;51(4):441-451. doi: 10.1111/jcpe.13919. Epub 2023 
      Dec 30.