PMID- 38160889
OWN - NLM
STAT- MEDLINE
DCOM- 20240209
LR  - 20240309
IS  - 1573-2517 (Electronic)
IS  - 0165-0327 (Print)
IS  - 0165-0327 (Linking)
VI  - 349
DP  - 2024 Mar 15
TI  - Prospectively assessed summer mood status in major depression, recurrent with 
      seasonal pattern: Evidence for SAD's construct validity.
PG  - 32-38
LID - S0165-0327(23)01538-0 [pii]
LID - 10.1016/j.jad.2023.12.070 [doi]
AB  - OBJECTIVE: Seasonal patterns are often undetectable in population-based 
      depression studies, calling into question the existence of winter seasonal 
      affective disorder (SAD). If SAD has construct validity, individuals with SAD 
      should show spontaneous depression remission in the summer. Data are sparse on 
      prospectively assessed summer mood status in confirmed SAD patients. METHOD: We 
      conducted prospective summer followup of community adults who, the winter before, 
      were diagnosed with Major Depression, Recurrent with Seasonal Pattern on the 
      Structured Clinical Interview for DSM-IV Axis I Disorders, developed a current 
      SAD episode on the Structured Interview Guide for the Hamilton Rating Scale for 
      Depression-Seasonal Affective Disorder Version (SIGH-SAD), and enrolled in a 
      clinical trial comparing group cognitive-behavioral therapy for SAD and light 
      therapy. In July/August after treatment, 143/153 (93.5 %) participants provided 
      data on the SIGH-SAD, the Beck Depression Inventory-Second Edition, and the 
      Longitudinal Interval Followup Evaluation (LIFE). RESULTS: Summer mean depression 
      scores were in the normal range, with the substantial majority in remission 
      across different measures. On the LIFE, 113/143 (79.0 %) experienced complete 
      summer remission, 19/143 (13.3 %) experienced partial summer remission, and 
      11/143 (7.7 %) had major depression in the summer. Depression scores were 
      significantly lower at summer than post-treatment in both treatments, indicating 
      incomplete treatment response. LIMITATIONS: This was a single-site study with a 
      relatively homogeneous sample. CONCLUSIONS: Supporting construct validity for 
      SAD, the substantial majority experienced complete summer remission, with a 
      minority in partial remission and a very small minority in episode. Both 
      treatments left residual symptoms at treatment endpoint compared to summer.
CI  - Copyright (c) 2024 Elsevier B.V. All rights reserved.
FAU - Rohan, Kelly J
AU  - Rohan KJ
AD  - Department of Psychological Science, University of Vermont, John Dewey Hall, 2 
      Colchester Avenue, Burlington, VT 05405-0134, USA. Electronic address: 
      kelly.rohan@uvm.edu.
FAU - Terman, Julia M
AU  - Terman JM
AD  - Department of Psychological Science, University of Vermont, John Dewey Hall, 2 
      Colchester Avenue, Burlington, VT 05405-0134, USA.
FAU - Iyiewuare, Praise
AU  - Iyiewuare P
AD  - Department of Psychological Science, University of Vermont, John Dewey Hall, 2 
      Colchester Avenue, Burlington, VT 05405-0134, USA.
FAU - Perez, Jessica
AU  - Perez J
AD  - Department of Psychological Science, University of Vermont, John Dewey Hall, 2 
      Colchester Avenue, Burlington, VT 05405-0134, USA.
FAU - Camuso, Julia A
AU  - Camuso JA
AD  - Department of Psychological Science, University of Vermont, John Dewey Hall, 2 
      Colchester Avenue, Burlington, VT 05405-0134, USA.
FAU - Postolache, Teodor T
AU  - Postolache TT
AD  - Department of Psychiatry, University of Maryland School of Medicine, 685 West 
      Baltimore Street, MSTF Building Room 930, Baltimore, MD 21201, USA; Rocky 
      Mountain MIRECC for Suicide Prevention, 1700 N Wheeling Street, G-3-116M, Aurora, 
      CO 80045, USA.
FAU - DeSarno, Michael J
AU  - DeSarno MJ
AD  - Biomedical Statistics Research Core, University of Vermont Larner College of 
      Medicine, 25 Hills Building, 111 Colchester Avenue, Burlington, VT 05401-0134, 
      USA.
FAU - Vacek, Pamela M
AU  - Vacek PM
AD  - Biomedical Statistics Research Core, University of Vermont Larner College of 
      Medicine, 25 Hills Building, 111 Colchester Avenue, Burlington, VT 05401-0134, 
      USA.
LA  - eng
GR  - R01 MH078982/MH/NIMH NIH HHS/United States
PT  - Journal Article
DEP - 20231230
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Humans
MH  - Adult
MH  - *Depressive Disorder, Major/diagnosis/therapy
MH  - Seasons
MH  - Depression
MH  - Prospective Studies
MH  - *Seasonal Affective Disorder/diagnosis/therapy/psychology
MH  - Phototherapy
PMC - PMC10923172
MID - NIHMS1960234
OTO - NOTNLM
OT  - Cognitive-behavioral therapy
OT  - Construct validity
OT  - Depression remission
OT  - Light therapy
OT  - Seasonal affective disorder
COIS- Declaration of competing interest Dr. Rohan receives book royalties from Oxford 
      University Press for the treatment manual for the cognitive-behavioral therapy 
      for SAD intervention. The authors have no other potential competing interests.
EDAT- 2024/01/02 11:46
MHDA- 2024/02/09 06:42
PMCR- 2025/03/15
CRDT- 2023/12/31 19:16
PHST- 2023/09/01 00:00 [received]
PHST- 2023/12/05 00:00 [revised]
PHST- 2023/12/27 00:00 [accepted]
PHST- 2025/03/15 00:00 [pmc-release]
PHST- 2024/02/09 06:42 [medline]
PHST- 2024/01/02 11:46 [pubmed]
PHST- 2023/12/31 19:16 [entrez]
AID - S0165-0327(23)01538-0 [pii]
AID - 10.1016/j.jad.2023.12.070 [doi]
PST - ppublish
SO  - J Affect Disord. 2024 Mar 15;349:32-38. doi: 10.1016/j.jad.2023.12.070. Epub 2023 
      Dec 30.